Patents by Inventor Moo J. Cho

Moo J. Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FATTY ACID DERIVATIVES AND ANALOGS OF DRUGS
    Publication number: 20130053433
    Abstract: The present disclosure is directed to fatty acid-drug conjugates, the preparation and use thereof and long-chain (C10-25), both saturated and unsaturated, fatty acids and anhydrides useful for preparing drug conjugates.
    Type: Application
    Filed: January 5, 2011
    Publication date: February 28, 2013
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Moo J. Cho, Michael Hackett
  • Oral cyclosphorin formulations
    Patent number: 6254885
    Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of admiration in hard capsules are provided. In the subject formations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formalations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: July 3, 2001
    Assignees: SangStat Medical Corporation, The University of North Carolina at Chapel Hill
    Inventors: Moo J. Cho, Ralph E. Levy, Philippe J. Pouletty
  • Oral cyclosporin formulations
    Patent number: 5962019
    Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of administration in both liquid and hard capsule form are provided. In the subject formulations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formulations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
    Type: Grant
    Filed: October 23, 1997
    Date of Patent: October 5, 1999
    Assignees: SangStat Medical Corporation, University of North Carolina at Chapel Hill
    Inventors: Moo J. Cho, Ralph E. Levy, Philippe J. Pouletty
  • Oral cyclopsporin formulations
    Patent number: 5834017
    Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of administration in hard capsules, are provided. In the subject formulations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant and an ester of an alcohol and a fatty acid having a hydrocarbon chain of from 14 to 18 carbon atoms. The subject formulations find use in immunosuppressive therapy.
    Type: Grant
    Filed: August 25, 1995
    Date of Patent: November 10, 1998
    Assignee: SangStat Medical Corporation
    Inventors: Moo J. Cho, Ralph F. Levy, Philippe J. Pouletty
  • Oral cyclosporin formulations
    Patent number: 5766629
    Abstract: Improved oral cyclosporin formulations which have high bioavailability and are capable of administration in hard capsules are provided. In the subject formulations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol solvent of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant. The subject formulations may further comprise at least one cosolvent, where cosolvents of interest include fatty acids and diols. The subject formulations find use in immuno-suppressive therapy.
    Type: Grant
    Filed: March 21, 1996
    Date of Patent: June 16, 1998
    Assignee: SangStat Medical Corporation
    Inventors: Moo J. Cho, Ralph E. Levy, Philippe J. Pouletty
  • N-substituted derivatives of 2-(pyridylalkenesulfinyl) benzimidazoles as gastric antisecretory agents
    Patent number: 4873337
    Abstract: The present invention provides novel N-substituted derivatives 2-(pyridylalkylenesulfinyl)benzimidazoles with gastric acid inhibiting effects.
    Type: Grant
    Filed: August 3, 1987
    Date of Patent: October 10, 1989
    Assignee: The Upjohn Company
    Inventors: John C. Sih, Moo J. Cho
  • Stabilization of PGI.sub.2 compounds with surfactants
    Patent number: 4430340
    Abstract: The present invention provides novel methods for the stabilization of aqueous solutions of prostacyclin and related prostacyclin analogs comprising the addition of neutral or cationic surfactants to such aqueous solutions. Additionally, the novel surfactant-containing solutions of prostacyclin and related compounds are described. Finally there are provided novel pharmaceutical compositions comprising surfactant-containing aqueous solutions of prostacyclin and related compounds.
    Type: Grant
    Filed: July 17, 1978
    Date of Patent: February 7, 1984
    Assignee: The Upjohn Company
    Inventor: Moo J. Cho
  • Metronidazole phosphate and salts
    Patent number: 4160827
    Abstract: This invention relates to novel compounds of the formula: ##STR1## wherein X.sup..sym. is a pharmacologically acceptable cation. The compounds are water soluble and are compounded with pharmaceutical carriers to form compositions which are useful as medical treatment for those conditions for which metronidazole is useful in treating.
    Type: Grant
    Filed: February 6, 1978
    Date of Patent: July 10, 1979
    Assignee: The Upjohn Company
    Inventors: Moo J. Cho, John J. Biermacher