Abstract: In one aspect of the invention, there is provided a nanoparticle comprising a core and a shell, wherein the core comprises a bioactive compound, and the shell comprises a lipid layer comprising a first modified lipid and a additional lipid, wherein the first modified lipid is bound to a targeted moiety via a spacer, and wherein the additional lipid comprises a polymer-bound lipid. The present invention further provides pharmaceutical compositions and methods for therapeutic and/or diagnostic use.

Abstract: The invention disclosed provides a device and method for recommending at least a product or a plurality of products to a user based at least in part on opinion-based criteria. The invention proceeds by first choosing a plurality of products in a category. At least one product in the category is associated with at least one rating. The rating comprises a rating of a plurality of criteria, and the plurality of criteria comprises opinion-based criteria. In the next step of the method of the invention, a calculation of product recommendability of the plurality of products is made (caused to be made) based on a selection by at least one user of an importance level of a plurality of criteria. Then at least one product recommendation is provided (received) based on the selection by at least one user of an importance level of a plurality of criteria and the opinion-based criteria.