Patents by Inventor Moran Grossman

Moran Grossman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of generating antibodies to metalloenzymes
    Patent number: 10066024
    Abstract: A method of generating an antibody which inhibits a metalloenzyme is disclosed. The method comprises immunizing a subject with: (i) a synthetic zinc mimicry compound having structural and electronic properties similar to a catalytic domain of the metalloenzyme; and (ii) the metalloenzyme, Antibodies generated by this method are also disclosed as well as uses thereof.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: September 4, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irit Sagi, Netta Sela-Paswell, Moran Grossman
  • Antibodies targeted against LOXL-2 for the treatment of collagen-associated pathologies
    Patent number: 10040868
    Abstract: An article of manufacture is disclosed which comprises at least two active agents, wherein a first of the two active agents comprises an anti-cancer agent or an antifibrotic agent and a second of the at least two active agents downregulates the activity and/or expression of lysyl-oxidase like protein-2 (LOXL-2) and which is capable of altering the structure of the extracellular matrix.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: August 7, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irit Sagi, Moran Grossman, Nir Ben-Chetrit
  • ANTIBODIES TARGETED AGAINST LOXL-2 FOR THE TREATMENT OF COLLAGEN-ASSOCIATED PATHOLOGIES
    Publication number: 20170210823
    Abstract: An article of manufacture is disclosed which comprises at least two active agents, wherein a first of the two active agents comprises an anti-cancer agent or an antifibrotic agent and a second of the at least two active agents downregulates the activity and/or expression of lysyl-oxidase like protein-2 (LOXL-2) and which is capable of altering the structure of the extracellular matrix.
    Type: Application
    Filed: July 24, 2014
    Publication date: July 27, 2017
    Inventors: Irit SAGI, Moran GROSSMAN, Nir BEN-CHETRIT
  • METHODS OF GENERATING ANTIBODIES TO METALLOENZYMES
    Publication number: 20130209491
    Abstract: A method of generating an antibody which inhibits a metalloenzyme is disclosed. The method comprises immunizing a subject with: (i) a synthetic zinc mimicry compound having structural and electronic properties similar to a catalytic domain of the metalloenzyme; and (ii) the metalloenzyme, Antibodies generated by this method are also disclosed as well as uses thereof.
    Type: Application
    Filed: October 27, 2011
    Publication date: August 15, 2013
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Irit Sagi, Netta Sela-Paswell, Moran Grossman