Patents by Inventor Moreland David Gibbs
Moreland David Gibbs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230183559Abstract: Novel hyperthermophilic Dictyoglomus beta-mannanases are provided for use in high temperature industrial applications requiring enzymatic hydrolysis of 1,4-?-D-mannosidic linkages in mannans, galactomannans, and glucomannans. Also provided are methods and compositions for fracturing a subterranean formation in which a gellable fracturing fluid is first formed by blending together a hydratable polymer and a Dictyoglomus beta-mannanase as an enzyme breaker. An optimized and stabilized recombinant Dictyoglomus beta-mannanase is provided that shows superior performance/effectiveness and properties in degrading guar and derivatized guars at pH ranges from 3.0 to 12 and temperatures ranging from 130° F. to in excess of 270° F.Type: ApplicationFiled: July 22, 2022Publication date: June 15, 2023Inventors: Robert Muko Tjon-Joe-Pin, Moreland David Gibbs, Valentino Setoa Junior Te'o
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Patent number: 11401457Abstract: Novel hyperthermophilic Dictyoglomus beta-mannanases are provided for use in high temperature industrial applications requiring enzymatic hydrolysis of 1,4-?-D-mannosidic linkages in mannans, galactomannans, and glucomannans. Also provided are methods and compositions for fracturing a subterranean formation in which a gellable fracturing fluid is first formed by blending together a hydratable polymer and a Dictyoglomus beta-mannanase as an enzyme breaker. An optimized and stabilized recombinant Dictyoglomus beta-mannanase is provided that shows superior performance/effectiveness and properties in degrading guar and derivatized guars at pH ranges from 3.0 to 12 and temperatures ranging from 130° F. to in excess of 270° F.Type: GrantFiled: December 6, 2018Date of Patent: August 2, 2022Assignee: Advanced Enzyme Systems, LLCInventors: Robert Muko Tjon-Joe-Pin, Moreland David Gibbs, Valentino Setoa Junior Te'o
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Patent number: 10377983Abstract: The invention relates to methods of producing a diatom biomass. More particularly, the invention relates to methods to produce a diatom biomass using a continuous culture to produce a volumetric production rate of biomass of at least 20 g dry weight/L/day, wherein the culture medium is designed to provide the essential nutrients to maintain the diatom in log phase growth. In a preferred cmbodimcnt the biomass comprises highly unsaturated fatty acid.Type: GrantFiled: December 12, 2017Date of Patent: August 13, 2019Assignee: FERMENTALGInventors: Mark Humphrey Dines, Hywel David Griffiths, Moreland David Gibbs
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Publication number: 20190093004Abstract: Novel hyperthermophilic Dictyoglomus beta-mannanases are provided for use in high temperature industrial applications requiring enzymatic hydrolysis of 1,4-?-D-mannosidic linkages in mannans, galactomannans, and glucomannans. Also provided are methods and compositions for fracturing a subterranean formation in which a gellable fracturing fluid is first formed by blending together a hydratable polymer and a Dictyoglomus beta-mannanase as an enzyme breaker. An optimized and stabilized recombinant Dictyoglomus beta-mannanase is provided that shows superior performance/effectiveness and properties in degrading guar and derivatized guars at pH ranges from 3.0 to 12 and temperatures ranging from 130° F. to in excess of 270° F.Type: ApplicationFiled: December 6, 2018Publication date: March 28, 2019Applicant: Advanced Enzyme Systems, LLCInventors: Robert Muko Tjon-Joe-Pin, Moreland David Gibbs, Valentino Setoa Junior Te'o
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Patent number: 10227523Abstract: Novel hyperthermophilic Dictyoglomus beta-mannanases are provided for use in high temperature industrial applications requiring enzymatic hydrolysis of 1,4-?-D-mannosidic linkages in mannans, galactomannans, and glucomannans. Also provided are methods and compositions for fracturing a subterranean formation in which a gellable fracturing fluid is first formed by blending together a hydratable polymer and a Dictyoglomus beta-mannanase as an enzyme breaker. An optimized and stabilized recombinant Dictyoglomus beta-mannanase is provided that shows superior performance/effectiveness and properties in degrading guar and derivatized guars at pH ranges from 3.0 to 12 and temperatures ranging from 130° F. to in excess of 270° F.Type: GrantFiled: November 25, 2014Date of Patent: March 12, 2019Assignee: Advanced Enzyme Systems, LLCInventors: Robert Muko Tjon-Joe-Pin, Moreland David Gibbs, Valentino Setoa Junior Te'o
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Publication number: 20180230419Abstract: The invention relates to methods of producing a diatom biomass. More particularly, the invention relates to methods to produce a diatom biomass using a continuous culture to produce a volumetric production rate of biomass of at least 20 g dry weight/L/day, wherein the culture medium is designed to provide the essential nutrients to maintain the diatom in log phase growth. In a preferred cmbodimcnt the biomass comprises highly unsaturated fatty acid.Type: ApplicationFiled: December 12, 2017Publication date: August 16, 2018Inventors: Mark Humphrey Dines, Hywel David Griffiths, Moreland David Gibbs
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Patent number: 9879218Abstract: The invention relates to methods of producing a diatom biomass. More particularly, the invention relates to methods to produce a diatom biomass using a continuous culture to produce a volumetric production rate of biomass of at least 20 g dry weight/L/day, wherein the culture medium is designed to provide the essential nutrients to maintain the diatom in log phase growth. In a preferred embodiment the biomass comprises highly unsaturated fatty acid.Type: GrantFiled: November 21, 2013Date of Patent: January 30, 2018Assignee: FERMENTALGInventors: Mark Humphrey Dines, Hywel David Griffiths, Moreland David Gibbs
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Publication number: 20160201025Abstract: The invention relates to methods of producing a diatom biomass. More particularly, the invention relates to methods to produce a diatom biomass using a continuous culture to produce a volumetric production rate of biomass of at least 20 g dry weight/L/day, wherein the culture medium is designed to provide the essential nutrients to maintain the diatom in log phase growth. In a preferred embodiment the biomass comprises highly unsaturated fatty acid.Type: ApplicationFiled: November 21, 2013Publication date: July 14, 2016Inventors: Mark Humphrey Dines, Hywel David Griffiths, Moreland David Gibbs
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Publication number: 20150148267Abstract: Novel hyperthermophilic Dictyoglomus beta-mannanases are provided for use in high temperature industrial applications requiring enzymatic hydrolysis of 1,4-?-D-mannosidic linkages in mannans, galactomannans, and glucomannans. Also provided are methods and compositions for fracturing a subterranean formation in which a gellable fracturing fluid is first formed by blending together a hydratable polymer and a Dictyoglomus beta-mannanase as an enzyme breaker. An optimized and stabilized recombinant Dictyoglomus beta-mannanase is provided that shows superior performance/effectiveness and properties in degrading guar and derivatized guars at pH ranges from 3.0 to 12 and temperatures ranging from 130° F. to in excess of 270° F.Type: ApplicationFiled: November 25, 2014Publication date: May 28, 2015Applicant: ADVANCED ENZYME SYSTEMS, LLCInventors: Robert Muko Tjon-Joe-Pin, Moreland David Gibbs, Valentino Setoa Junior Te'o
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Patent number: 7771974Abstract: A method for gene shuffling to form a mutant or chimeric gene, the method comprising: (a) assigning one or more segments of one or more genes based on regions of encoded amino acid sequence; (b) amplifying the one or more assigned segments of the gene using primers specific for each segment; and (c) causing recombination of the one or more amplified segments to form a mutant or chimeric gene. An oligonucleotide primer suitable for use in gene shuffling, the primer having a non-degenerate core based on a segment or template of a gene to be amplified, and the core being flanked by both 5? and 3? degenerate ends.Type: GrantFiled: August 29, 2001Date of Patent: August 10, 2010Assignee: Macquarie UniversityInventors: Moreland David Gibbs, Peter Leonard Bergquist, Kaisu Milja Helena Nevalainen
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Patent number: 7504207Abstract: A method for producing a mutant gene encoding a functional gene product comprising: (a) introducing one or more mutations into a gene to form a mutated gene; (b) providing the mutated gene to a host microorganism; (c) culturing the host microorganism containing the mutated gene under conditions which allow expression of the mutant gene product; and (d) selecting a host microorganism capable of producing a functional gene production from the mutated gene.Type: GrantFiled: October 7, 2003Date of Patent: March 17, 2009Assignee: Macquarie UniversityInventors: Peter Leonard Bergquist, Moreland David Gibbs, Rosalind Reeves
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Publication number: 20040053267Abstract: A method for gene shuffling to form a mutant or chimeric gene, the method comprising: (a) assigning one or more segments of one or more genes based on regions of encoded amino acid sequence; (b) amplifying the one or more assigned segments of the gene using primers specific for each segment; and (c) causing recombination of the one or more amplified segments to form a mutant or chimeric gene. An oligonucleotide primer suitable for use in gene shuffling, the primer having a non-degenerate core based on a segment or template of a gene to be amplified, and the core being flanked by both 5′ and 3′ degenerate ends.Type: ApplicationFiled: July 1, 2003Publication date: March 18, 2004Inventors: Moreland David Gibbs, Peter Leonard Bergquist, Kaisu Milja Helena Nevalainen
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Patent number: 6294366Abstract: Alkalophilic and thermophilic cellulases having high stability to elevated temperatures and pH have been isolated from an organism of unknown species, which most closely resembles those in the Caldicellulosiruptor genus and which has been called by us, Tok7B.1, These cellulases have been cloned and expressed in a recombinant system, so that they can be produced in quantity. These are particularly useful in treating cellulosic materials including cotton-containing fabrics, as detergent additives, and in aqueous compositions. We also provide genomic DNA which can be used in recombinant expression vectors and expression systems to produce enhanced alkali and/or temperature stability properties in cellulases other than those specifically described.Type: GrantFiled: August 19, 1998Date of Patent: September 25, 2001Assignee: Clariant Finance (BVI) LimitedInventors: Graham K. Farrington, Paige Anderson, Peter Bergquist, Roy Daniels, Moreland David Gibbs, Hugh Morgan, Diane P. Williams