Patents by Inventor Morgan B. Giles

Morgan B. Giles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230201121
    Abstract: A drug delivery system comprises a porous, self-healing biodegradable polymer matrix having a ionic, charged, biopolymer and a pH modifying species disposed within the pores. An ionic macromolecule having the opposite charge binds the biopolymer and forms a nonsoluble polyelectrolyte complex. The molecular weight of the biopolymer, the self healing polymer matrix, the concentration of pore forming agent and the concentration of the pH modifying species are selected for optimal binding and release of the macromolecule.
    Type: Application
    Filed: February 9, 2023
    Publication date: June 29, 2023
    Inventors: Steven Paul Schwendeman, Ronak B. Shah, Morgan B. Giles, Rae Sung Chang, Anna A. Schwendeman
  • Publication number: 20230149296
    Abstract: This invention relates to novel implant drug delivery systems for long-acting delivery of antiviral and contraceptive drugs. These compositions are useful for the treatment or prevention of human immunodeficiency virus (HIV) infection and the prevention of pregnancy.
    Type: Application
    Filed: April 30, 2021
    Publication date: May 18, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Morgan B. Giles, Seth P. Forster, Stephanie Elizabeth Barrett, Athanas Koynov, Ryan S. Teller
  • Publication number: 20230086256
    Abstract: This invention relates to novel implant drug delivery systems for long-acting delivery of mometasone furoate. These compositions are useful for the treatment or prevention of inflammatory conditions of the eye.
    Type: Application
    Filed: January 22, 2021
    Publication date: March 23, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Morgan B. Giles, Seth P. Forster, Stephanie Elizabeth Barrett, Steven C. Persak
  • Patent number: 11607387
    Abstract: A drug delivery system comprises a porous, self-healing biodegradable polymer matrix having a ionic, charged, biopolymer and a pH modifying species disposed within the pores. An ionic macromolecule having the opposite charge binds the biopolymer and forms a nonsoluble polyelectrolyte complex. The molecular weight of the biopolymer, the self healing polymer matrix, the concentration of pore forming agent and the concentration of the pH modifying species are selected for optimal binding and release of the macromolecule.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: March 21, 2023
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Steven P. Schwendeman, Ronak B. Shah, Morgan B. Giles, Rae Sung Chang, Anna A. Schwendeman
  • Publication number: 20220362277
    Abstract: This invention relates to novel implant drug delivery systems for long-acting delivery of antiviral drugs. These compositions are useful for the treatment or prevention of human immunodeficiency virus (HIV) infection.
    Type: Application
    Filed: August 11, 2020
    Publication date: November 17, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Seth P. Forster, Stephanie Elizabeth Barrett, Ryan S. Teller, Morgan B. Giles, Athanas Koynov
  • Publication number: 20200022916
    Abstract: A drug delivery system comprises a porous, self-healing biodegradable polymer matrix having a ionic, charged, biopolymer and a pH modifying species disposed within the pores. An ionic macromolecule having the opposite charge binds the biopolymer and forms a nonsoluble polyelectrolyte complex. The molecular weight of the biopolymer, the self healing polymer matrix, the concentration of pore forming agent and the concentration of the pH modifying species are selected for optimal binding and release of the macromolecule.
    Type: Application
    Filed: August 5, 2019
    Publication date: January 23, 2020
    Inventors: Steven P. Schwendeman, Ronak B. Shah, Morgan B. Giles, Rae Sung Chang, Anna A. Schwendeman
  • Patent number: 10369106
    Abstract: A drug delivery system comprises a porous, self-healing biodegradable polymer matrix having a ionic, charged, biopolymer and a pH modifying species disposed within the pores. An ionic macromolecule having the opposite charge binds the biopolymer and forms a nonsoluble polyelectrolyte complex. The molecular weight of the biopolymer, the self healing polymer matrix, the concentration of pore forming agent and the concentration of the pH modifying species are selected for optimal binding and release of the macromolecule.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: August 6, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Steven P. Schwendeman, Ronak B. Shah, Morgan B. Giles, Rae Sung Chang, Anna A. Schwendeman
  • Publication number: 20150164805
    Abstract: A drug delivery system comprises a porous, self-healing biodegradable polymer matrix having a ionic, charged, biopolymer and a pH modifying species disposed within the pores. An ionic macromolecule having the opposite charge binds the biopolymer and forms a nonsoluble polyelectrolyte complex. The molecular weight of the biopolymer, the self healing polymer matrix, the concentration of pore forming agent and the concentration of the pH modifying species are selected for optimal binding and release of the macromolecule.
    Type: Application
    Filed: November 10, 2014
    Publication date: June 18, 2015
    Inventors: Steven P. Schwendeman, Ronak B. Shah, Morgan B. Giles, Rae Sung Chang, Anna A. Schwendeman