Patents by Inventor Morgan Brophy
Morgan Brophy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230173224Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient’s natural cerebrospinal fluid (CSF) pulsation or the patient’s heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: ApplicationFiled: January 10, 2023Publication date: June 8, 2023Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl, Ayesha Arzumand, Stela Moura, Andrew East, Jonathan Freund
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Publication number: 20210093844Abstract: Systems and methods for flushing shunt systems are disclosed herein. In some embodiments, a flusher includes a pinch tube that extends over a flush dome such that a user can simultaneously close the pinch tube and actuate the flush dome with a single motion. Flushing and refill valves of the system can be disposed in a cartridge that is laterally-offset from the flush dome, advantageously reducing the height profile of the flusher. Flushers with integrated shunt valves are also disclosed, as are shunt systems with restricted and unrestricted modes for selectively limiting the instances in which a user can open an auxiliary flow path through the system.Type: ApplicationFiled: October 5, 2020Publication date: April 1, 2021Applicant: Anuncia, Inc.Inventors: PJ Anand, Deep Arjun Singh, Greg Eberl, Andrew East, Morgan Brophy, Ayesha Arzumand, Stela Moura, Loredana Guseila
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Publication number: 20210052820Abstract: Automated drug delivery systems and related methods are disclosed herein. In some embodiments, these systems can reduce or eliminate infusion inconsistencies. An exemplary system can include a syringe actuator which can be controlled via electrical, mechanical, pneumatic, and/or hydraulic means to precisely infuse and/or withdraw material from a patient.Type: ApplicationFiled: November 9, 2020Publication date: February 25, 2021Inventors: PJ Anand, Ayesha Arzumand, Morgan Brophy, Andrew East, Gregory Eberl, Deep Arjun Singh
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Publication number: 20210016068Abstract: Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imageable portions (e.g., portions which are visible under magnetic resonance imaging (MRI)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRI, thereby providing a reliable indication as to whether the catheter is partially or completely blocked.Type: ApplicationFiled: May 4, 2020Publication date: January 21, 2021Inventors: PJ Anand, Deep Arjun Singh, Morgan Brophy, Timothy Fallon, Robert Degon, Matthew Attar, Anthony Wong, Allison Waller, Andrew East, Jon T. McIntyre
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Patent number: 10828424Abstract: Automated drug delivery systems and related methods are disclosed herein. In some embodiments, these systems can reduce or eliminate infusion inconsistencies. An exemplary system can include a syringe actuator which can be controlled via electrical, mechanical, pneumatic, and/or hydraulic means to precisely infuse and/or withdraw material from a patient.Type: GrantFiled: July 28, 2017Date of Patent: November 10, 2020Assignee: ALCYONE LIFESCIENCES, INC.Inventors: PJ Anand, Ayesha Arzumand, Morgan Brophy, Andrew East, Gregory Eberl, Deep Arjun Singh
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Patent number: 10792480Abstract: Systems and methods for flushing shunt systems are disclosed herein. In some embodiments, a flusher includes a pinch tube that extends over a flush dome such that a user can simultaneously close the pinch tube and actuate the flush dome with a single motion. Flushing and refill valves of the system can be disposed in a cartridge that is laterally-offset from the flush dome, advantageously reducing the height profile of the flusher. Flushers with integrated shunt valves are also disclosed, as are shunt systems with restricted and unrestricted modes for selectively limiting the instances in which a user can open an auxiliary flow path through the system.Type: GrantFiled: October 12, 2017Date of Patent: October 6, 2020Assignee: Anuncia, Inc.Inventors: P J Anand, Deep Arjun Singh, Greg Eberl, Andrew East, Morgan Brophy, Ayesha Arzumand, Stela Moura, Loredana Guseila
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Publication number: 20200275948Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient's natural cerebrospinal fluid (CSF) pulsation or the patient's heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: ApplicationFiled: May 18, 2020Publication date: September 3, 2020Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl, Ayesha Arzumand, Stela Moura
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Publication number: 20200197676Abstract: Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imagable portions (e.g., portions which are visible under magnetic resonance imaging (MRI)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRI, thereby providing a reliable indication as to whether the catheter is partially or completely blocked.Type: ApplicationFiled: November 21, 2019Publication date: June 25, 2020Inventors: Andrew East, Morgan Brophy, Deep Arjun Singh, PJ Anand, Robert Degon, Timothy Fallon, Allison Waller, Matthew Attar
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Patent number: 10653442Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient's natural cerebrospinal fluid (CSF) pulsation or the patient's heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: GrantFiled: December 21, 2017Date of Patent: May 19, 2020Assignee: ALCYONE LIFESCIENCES, INC.Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl, Ayesha Arzumand, Stela Moura
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Patent number: 10639461Abstract: Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imageable portions (e.g., portions which are visible under magnetic resonance imaging (MRI)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRI, thereby providing a reliable indication as to whether the catheter is partially or completely blocked.Type: GrantFiled: March 17, 2017Date of Patent: May 5, 2020Assignee: Anuncia, Inc.Inventors: P J Anand, Deep Arjun Singh, Morgan Brophy, Timothy Fallon, Robert Degon, Matthew Attar, Anthony Wong, Allison Waller, Andrew East, Jon T. McIntyre
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Publication number: 20190374715Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient's natural cerebrospinal fluid (CSF) pulsation or the patient's heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: ApplicationFiled: August 21, 2019Publication date: December 12, 2019Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl
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Patent number: 10493249Abstract: Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imageable portions (e.g., portions which are visible under magnetic resonance imaging (MRI)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRI, thereby providing a reliable indication as to whether the catheter is partially or completely blocked.Type: GrantFiled: July 20, 2017Date of Patent: December 3, 2019Assignee: Anuncia, Inc.Inventors: Andrew East, Morgan Brophy, Deep Arjun Singh, PJ Anand, Robert Degon, Timothy Fallon, Allison Waller, Matthew Attar
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Publication number: 20190314574Abstract: Percutaneous therapy or drug delivery devices are described herein. The device can include one or multiple lumens inside a cannula or catheter body. The device can include features for reducing or preventing backflow or reflux of infusate along the device insertion track, such as one or more bullet noses, over tubes, and/or micro-tips. The device can be used in any of a variety of treatment methods, including to inject cancer therapy medicinal products directly into pulmonary tumors or tumors located in other regions of the body. The device can include features to keep the distal tip secure during patient respiration or during other patient movement, and can reduce the incidence of reflux during therapy delivery.Type: ApplicationFiled: February 27, 2019Publication date: October 17, 2019Inventors: Katelyn Perkins-Neaton, Gregory Eberl, Morgan Brophy, Andrew East, PJ Anand, Deep Arjun Singh, Loredana Guseila, Jon Freund, Derek Peter
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Patent number: 10406285Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient's natural cerebrospinal fluid (CSF) pulsation or the patient's heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: GrantFiled: May 25, 2017Date of Patent: September 10, 2019Assignee: ALCYONE LIFESCIENCES, INC.Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl
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Publication number: 20190160254Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient's natural cerebrospinal fluid (CSF) pulsation or the patient's heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: ApplicationFiled: November 15, 2018Publication date: May 30, 2019Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl, Ayesha Arzumand, Stela Moura, Andrew East, Jonathan Freund
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Publication number: 20180185058Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient's natural cerebrospinal fluid (CSF) pulsation or the patient's heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: ApplicationFiled: December 21, 2017Publication date: July 5, 2018Applicant: Alcyone Lifesciences, Inc.Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl, Ayesha Arzumand, Stela Moura
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Publication number: 20180104459Abstract: Systems and methods for flushing shunt systems are disclosed herein. In some embodiments, a flusher includes a pinch tube that extends over a flush dome such that a user can simultaneously close the pinch tube and actuate the flush dome with a single motion. Flushing and refill valves of the system can be disposed in a cartridge that is laterally-offset from the flush dome, advantageously reducing the height profile of the flusher. Flushers with integrated shunt valves are also disclosed, as are shunt systems with restricted and unrestricted modes for selectively limiting the instances in which a user can open an auxiliary flow path through the system.Type: ApplicationFiled: October 12, 2017Publication date: April 19, 2018Applicant: Alcyone Lifesciences, Inc.Inventors: PJ Anand, Deep Arjun Singh, Greg Eberl, Andrew East, Morgan Brophy, Ayesha Arzumand, Stela Moura, Loredana Guseila
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Publication number: 20180064919Abstract: Systems and methods are provided herein that generally involve shunting fluid, e.g., shunting cerebrospinal fluid in the treatment of hydrocephalus. Self-cleaning catheters are provided which include split tips configured such that pulsatile flow of fluid in a cavity in which the catheter is inserted can cause the tips to strike one another and thereby clear obstructions. Catheters with built-in flow indicators are also provided. Exemplary flow indicators include projections that extend radially inward from the interior surface of the catheter and which include imageable portions (e.g., portions which are visible under magnetic resonance imaging (MRI)). Movement of the flow indicators caused by fluid flowing through the catheter can be detected using MRI, thereby providing a reliable indication as to whether the catheter is partially or completely blocked.Type: ApplicationFiled: July 20, 2017Publication date: March 8, 2018Applicant: Alcyone Lifesciences, Inc.Inventors: Andrew East, Morgan Brophy, Deep Arjun Singh, PJ Anand, Robert Degon, Timothy Fallon, Allison Waller, Matthew Attar
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Publication number: 20180028761Abstract: Automated drug delivery systems and related methods are disclosed herein. In some embodiments, these systems can reduce or eliminate infusion inconsistencies. An exemplary system can include a syringe actuator which can be controlled via electrical, mechanical, pneumatic, and/or hydraulic means to precisely infuse and/or withdraw material from a patient.Type: ApplicationFiled: July 28, 2017Publication date: February 1, 2018Applicant: Alcyone Lifesciences, Inc.Inventors: PJ Anand, Ayesha Arzumand, Morgan Brophy, Andrew East, Gregory Eberl, Deep Arjun Singh
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Publication number: 20170258996Abstract: Drug delivery systems and methods are disclosed herein. In some embodiments, a drug delivery system can be configured to deliver a drug to a patient in coordination with a physiological parameter of the patient (e.g., the patient's natural cerebrospinal fluid (CSF) pulsation or the patient's heart or respiration rate). In some embodiments, a drug delivery system can be configured to use a combination of infusion and aspiration to control delivery of a drug to a patient. Catheters, controllers, and other components for use in the above systems are also disclosed, as are various methods of using such systems.Type: ApplicationFiled: May 25, 2017Publication date: September 14, 2017Applicant: Alcyone Lifesciences, Inc.Inventors: PJ Anand, Morgan Brophy, Deep Arjun Singh, Greg Eberl