Abstract: Three-dimensional body implants including a hydrogel, which includes cross-linked alginate and gelatin, and in particular breast implants. The hydrogel of the implants has a mechanical strength of 1 kPa to 1000 kPa, and the hydrogel of the implants may further include fibrinogen. The implants include a porous zone, and the implants are acellular, i.e., free of cells during their manufacture.

Abstract: A teeth whitening based on the generation of active oxygen in the form of oxygen radical species in situ and method for producing the whitening gel which has modified niobium compounds and its activity maximized if applied with hydrogen peroxide in low concentrations, with stabilization by a thickener. The whitening gel can be used without light treatment and with greater efficiency than commercial products and with a significant potential to reduce side effects. The whitening toothpaste and gels including modified niobium compounds associated with cations, the mechanisms of whitening action comes from electronic excitation, from the incidence of radiation on niobium compounds with cations, due to the action of the functional chemical groups present in the nanoparticles, even in the absence of light. In addition, the compounds can act as chemical whiteners, leading to a decrease in caries bacteria due to the oxidant functional groups in the nanoparticles.

Abstract: The invention relates to a method for manufacturing a bio-ink by additive deposition, which comprises supplying: a first solution including between 5 and 40 wt. % gelatin; a second solution including between 15 and 35.wt. % alginate; a third solution including between 1 and 15 wt. % fibrinogen, and optionally living cells in suspension; and creating a mixture including: around 35 to 65 vol. % of the first solution; around 15 to 35 vol. % of the second solution; and around 15 to 35 vol. % of the third solution, said proportions being selected so that they add up to 100%. Said bio-ink allows the additive deposition of objects that can be polymerised by means of a solution including calcium ions and thrombin. Said objects can be incubated and can be used as a substitute for body tissue, for example (with added fibroblasts) as skin substitute.

Abstract: The invention relates to a method for manufacturing a bio-ink by additive deposition, which comprises supplying: a first solution including between 5 and 40 wt. % gelatin; a second solution including between 15 and 35 .wt. % alginate; a third solution including between 1 and 15 wt. % fibrinogen, and optionally living cells in suspension; and creating a mixture including: around 35 to 65 vol. % of the first solution; around 15 to 35 vol. % of the second solution; and around 15 to 35 vol. % of the third solution, said proportions being selected so that they add up to 100%. Said bio-ink allows the additive deposition of objects that can be polymerised by means of a solution including calcium ions and thrombin. Said objects can be incubated and can be used as a substitute for body tissue, for example (with added fibroblasts) as skin substitute.

Abstract: The present invention relates to the cosmetic use by the topical route of a Tapirira guianensis extract, for stimulating the expression of perlecan and/or dystroglycan and/or VE-cadherin and/or claudin-5, in particular in the extracellular matrix and/or in the epithelial basement membrane, especially the dermoepidermal junction. It also relates to a cosmetic care method comprising the application, to at least one concerned area of healthy skin and/or healthy mucous membrane and/or healthy scalp, of a Tapirire guianensis extract or of a cosmetic composition comprising such an extract for stimulating the expression of perlecan and/or dystroglycan and/or VE-cadherin and/or claudin-5, in particular in the extracellular matrix and/or in the epithelial basement membrane, especially the dermoepidermal junction. In addition, it relates to a cosmetic composition comprising a Tapirira guianensis extract and a topically acceptable cosmetic excipient.