Abstract: An example ceramic panel has a first surface and a second surface. The ceramic panel has a bond finger well on the first surface of the ceramic panel a scribe line well on the second surface of the ceramic panel. The ceramic panel also has a scribe line along the scribe line well.

Abstract: A surgical instrument is disclosed herein. The surgical instrument can include an end effector that includes jaws configured to transition between an opened condition and a closed condition, a plurality of electrodes positioned within the jaws of the end effector, a control circuit, and a memory configured to store an algorithm configured to cause the control circuit to determine an impedance signal based on signals received from the plurality of electrodes, detect a media positioned between the jaws of the end effector based on the determined impedance signal, determine a position of the detected media based on the received signals, and generate an alert associated with the detected media and the determined position.

Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: A structure for a handheld device with a function of electrostatic discharge (ESD) protection has a circuit member (230), a displaying member (240), and a conductive supporting frame (250) with a hollow region (251). The circuit member and the displaying member are affixed to the conductive supporting frame at the hollow region to construct a subassembly (300). The subassembly is then mounted in a housing (202) consisting of upper and lower housings (210,212) at a location that the conductive supporting frame is just beside a gap (203) between the upper and lower housings. ESD-sensitive components (231,232) on the circuit member and the displaying member are surrounded by the conductive supporting frame, whereby ESD entering the housing via the gap which may cause a harm to the ESD-sensitive components and the displaying member is absorbed by the supporting frame and transmitted to ground via an electrical connection between the supporting frame and ground trace of the circuit member.

Abstract: A structure for a handheld device with a function of electrostatic discharge (ESD) protection has a circuit member (230), a displaying member (240), and a conductive supporting frame (250) with a hollow region (251). The circuit member and the displaying member are affixed to the conductive supporting frame at the hollow region to construct a subassembly (300). The subassembly is then mounted in a housing (202) consisting of upper and lower housings (210,212) at a location that the conductive supporting frame is just beside a gap (203) between the upper and lower housings. ESD-sensitive components (231,232) on the circuit member and the displaying member are surrounded by the conductive supporting frame, whereby ESD entering the housing via the gap which may cause a harm to the ESD-sensitive components and the displaying member is absorbed by the supporting frame and transmitted to ground via an electrical connection between the supporting frame and ground trace of the circuit member.