Abstract: An inflation adaptor is provided to move a wire within a hollow tubular body, the movement of the wire enabling actuation of an expandable member at the distal end of the hollow tubular body. The expandable member can be a balloon, filter or similar device. The adaptor generally includes a clamping mechanism which clamps the hollow tubular body and wire within the adaptor, and also includes a drive mechanism for moving the wire within the hollow tubular body. An actuator, such as a rotatable knob, is provided to operate both the clamping mechanism and the drive mechanism. The adaptor may also include a fluid delivery and expansion system within a housing when the expandable member is a balloon, wherein movement of the actuator delivers a predetermined amount to the balloon while still operating the clamping mechanism and the drive mechanism.