Patents by Inventor Morgane Rousselot

Morgane Rousselot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heamoglobin and uses thereof
    Patent number: 11224218
    Abstract: The present invention relates to isolated haemoglobin from worms belonging to the Nereididae family and its use in cell culture medium, in preservation solutions and as artificial oxygen carrier for transfusion.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: January 18, 2022
    Assignee: HEMARINA
    Inventors: Morgane Rousselot, Delphine Dutheil, Franck Zal
  • Use of a hemoglobin for the preparation of dressings and resulting dressings
    Patent number: 11103615
    Abstract: The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: August 31, 2021
    Assignees: Centre National De La Recherche Scientifique CNRS, Hemarina, Universite Pierre Et Marie Curie
    Inventors: Franck Zal, Morgane Rousselot
  • ANNELID HAEMOGLOBIN LYOPHILISATION PROCESS
    Publication number: 20210113471
    Abstract: The present invention relates to a lyophilizate comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. The present invention also relates to a composition comprising: a solution comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. Finally, the present invention relates to a process for preparing the lyophilizate.
    Type: Application
    Filed: September 8, 2020
    Publication date: April 22, 2021
    Inventors: Franck Zal, Morgane Rousselot
  • Use of extracellular hemoglobin obtained from the marine worm, , for the preservation of organs, tissues, cells
    Patent number: 9861095
    Abstract: Disclosed is a method for preserving an organ in a donation after brain death donor or a donation after cardiac death donor comprising administering to the donor a composition comprising at least one globin, one globin protomer or one extracellular hemoglobin of Annelida, a stabilizing solution and/or a solution for conserving organs, said composition having a temperature of between 0° C. and 37° C. Also disclosed is a method for conserving an organ in situ in a donation after brain death donor or a donation after cardiac death donor using normothermic ECMO or double-balloon triple-lumen catheter techniques or any other similar technique.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: January 9, 2018
    Assignee: HEMARINA
    Inventors: Delphine Dutheil, Morgane Rousselot, Thierry Hauet, Franck Zal
  • Use of a Haemoglobin for the Preparation of Dressings and Resulting Dressings
    Publication number: 20160175478
    Abstract: The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings.
    Type: Application
    Filed: December 15, 2015
    Publication date: June 23, 2016
    Inventors: Franck Zal, Morgane Rousselot
  • Use of a haemoglobin for the preparation of dressings and resulting dressings
    Patent number: 9220929
    Abstract: The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings.
    Type: Grant
    Filed: June 10, 2008
    Date of Patent: December 29, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, Hemarina, UNIVERSITE PIERRE ET MARIE CURE
    Inventors: Franck Zal, Morgane Rousselot
  • ANNELID HAEMOGLOBIN LYOPHILISATION PROCESS
    Publication number: 20150190343
    Abstract: The present invention relates to a lyophilizate comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. The present invention also relates to a composition comprising: a solution comprising at least one globin, one globin protomer or one extracellular hemoglobin of annelids, and a stabilizer chosen from disaccharides, polyols and antioxidants. Finally, the present invention relates to a process for preparing the lyophilizate.
    Type: Application
    Filed: June 5, 2013
    Publication date: July 9, 2015
    Inventors: Franck Zal, Morgane Rousselot
  • Use of a globin, a globin protomer or an extracellular hemoglobin obtained from the marine worm, , for the preservation of organs, tissues, cells or cell cultures
    Patent number: 8846306
    Abstract: The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures.
    Type: Grant
    Filed: July 25, 2008
    Date of Patent: September 30, 2014
    Assignees: Hemarina SA, Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie (Paris 6)
    Inventors: Franck Zal, Morgane Rousselot, Delphine Dutheil
  • ORGAN-PRESERVING COMPOSITION AND USES
    Publication number: 20140113274
    Abstract: The invention relates to the use of a composition comprising at least one globin, one globin protomer or one extracellular hemoglobin of Annelida, a stabilizing solution and/or a solution for conserving organs, said composition having a temperature of between 0° C. and 37° C., for preserving an organ in a donation after brain death donor or a donation after cardiac death donor. The invention also relates to a method for conserving an organ in situ in a donation after brain death donor or a donation after cardiac death donor using normothermic ECMO or double-balloon triple-lumen catheter techniques or any other similar technique.
    Type: Application
    Filed: May 30, 2012
    Publication date: April 24, 2014
    Applicant: HEMARINA
    Inventors: Delphine Dutheil, Morgane Rousselot, Thierry Hauet, Franck Zal
  • NOVEL HEAMOGLOBIN AND USES THEREOF
    Publication number: 20120052136
    Abstract: The present invention relates to isolated haemoglobin from worms belonging to the Nereididae family and its use in cell culture medium, in preservation solutions and as artificial oxygen carrier for transfusion.
    Type: Application
    Filed: May 7, 2010
    Publication date: March 1, 2012
    Applicant: HEMARINA
    Inventors: Morgane Rousselot, Delphine Dutheil, Franck Zal
  • Use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing diseases by inhibition of calcium
    Patent number: 7999076
    Abstract: The present invention relates to the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing diseases by inhibition of calcium. Advantageously, the extracellular hemoglobin is obtained from Annelids. In particular, the invention concerns the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing cardiovascular diseases, such as hypertension, angina such as angina pectoris, Raynaud's disease, arteriopathy, tachycardia, vasospasm, ischemia, myocardial infarction, congestive heart failure, arrhythmia or cerebrovacular accident.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: August 16, 2011
    Assignee: Centre National De La Recherche
    Inventors: Franck Zal, Morgane Rousselot
  • Use of a Haemoglobin for the Preparation of Dressings and Resulting Dressings
    Publication number: 20100278887
    Abstract: The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings.
    Type: Application
    Filed: June 10, 2008
    Publication date: November 4, 2010
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, HEMARINA SA, UNIVERSITE PIERRE ET MARIE CURIE
    Inventors: Franck Zal, Morgane Rousselot
  • Use Of A High Molecular Weight Extracellular Hemoglobin For The Manufacture Of A Medicament For Treating And/Or Preventing Diseases By Inhibition Of Calcium
    Publication number: 20100234275
    Abstract: The present invent ion relates to the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing diseases by inhibition of calcium. Advantageously, the extracellular hemoglobin is obtained from Annelids. In particular, the invention concerns the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing cardiovascular diseases, such as hypertension, angina such as angina pectoris, Raynaud's disease, arteriopathy, tachycardia, vasospasm, ischemia, myocardial infarct ion, congestive heart failure, arrhythmia or cerebrovacular accident.
    Type: Application
    Filed: January 23, 2007
    Publication date: September 16, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Franck Zal, Morgane Rousselot
  • Use of a Globin, a Globin Protomer or an Extracellular Hemoglobin for the Preservation of Organs, Tissues, Organ and Tissue Cells and Cell Cultures
    Publication number: 20100209902
    Abstract: The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures.
    Type: Application
    Filed: July 25, 2008
    Publication date: August 19, 2010
    Applicants: HEMARINA SA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Franck Zal, Morgane Rousselot, Delphine Dutheil
  • Method for the dissociation of the extracellular haemoglobin molecule of and the characterization of the protein chains forming the molecule and the nucleotide sequences coding for said protein chains
    Patent number: 7776526
    Abstract: Method of dissociating the extracellular haemoglobin molecule of annelids, e.g. Arenicola marina, which can be used to obtain the protein chains forming the molecule. The method includes a step of bringing an extracellular haemoglobin sample from annelids, e.g. Arenicola marina, into contact with at least one dissociating agent, e.g. a mixture containing dithiothreitol (DTT) or tris(2-carboxyethyl)phosphine (TCEP) hydrochloride or beta-mercaptoethanol and a dissociation buffer for a sufficient length of time in order to separate the protein chains from one another.
    Type: Grant
    Filed: October 13, 2004
    Date of Patent: August 17, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie
    Inventors: Franck Zal, Christine Chabasse, Morgane Rousselot, Xavier Bailly
  • Method for the dissociation of the extracellular haemoglobin molecule of arenicola marina and the characterisation of the protein chains forming the molecule and the nucleotide sequences coding for said protein chains
    Publication number: 20070037160
    Abstract: The invention relates to a method of dissociating the extracellular haemoglobin molecule of annelids, e.g. Arenicola marina, which can be used to obtain the protein chains forming said molecule. The inventive method is characterised in that it comprises a step consisting in bringing an extracellular haemoglobin sample from annelids, e.g. Arenicola marina, into contact with at least one dissociating agent, e.g. a mixture containing dithiothreitol (DTT) or tris(2-carboxyethyl)phosphine (TCEP) hydrochloride or beta-mercaptoethanol and a dissociation buffer for a sufficient length of time in order to separate the protein chains from one another.
    Type: Application
    Filed: October 13, 2004
    Publication date: February 15, 2007
    Inventors: Frank Zal, Christine Chabasse, Morgane Rousselot, Xavier Bailly