Abstract: A sealing rubber closure is provided for use with a syringe/container specified by ISO (the International Organization of Standardization) and having a Luer nozzle to be inserted into a Luer-nozzle-receiving part of the sealing rubber closure. The Luer-nozzle-receiving part is configured, on a side of an inner end portion thereof, in an untapered cylindrical form to assure tight-fitted insertion of a free end portion of the Luer nozzle and, on a side of a Luer-nozzle-receiving opening thereof, in a tapered, substantially cylindrical form to assure tight-fitted insertion of a basal end portion of the Luer nozzle. A plastic film is laminated on the sealing rubber closure at least in an area of the Luer-nozzle-receiving part, where a free end of the Luer nozzle is to be maintained in contact with the sealing rubber closure.

Abstract: A pre-filled syringe assembly is achieved which prevents, with a strong force, a stopper provided therein from being pulled out, and wherein the stopper can be prevented from being scratched.

Abstract: A cylindrical vial having a bottom, for a medicine, in which an open end of the cylindrical vial is sealed by a needle-penetrable rubber closure through which a needle can be penetrated, the cylindrical vial including a conical bottom end provided opposite to the open end, wherein the apex of the conical bottom end is located on a central axis of the cylindrical vial at the bottommost point inside the cylindrical vial.

Abstract: A molding die assembly includes an upper die and a lower die, wherein at least one of the upper and lower dies is provided with a cavity corresponding to the shape of a rubber member to be molded, wherein at least one of the upper and lower dies is provided with an annular projection around a cavity. The distance between the upper and lower dies at the annular projection is made smaller than the distance between the opposed surface portions, other than the cavity, of the upper and lower dies. A rubber member produced by the above mentioned molding die assembly is also provided.

Abstract: A closure for a vial includes a head portion, and a stem portion which projects from a lower surface of the head portion, the stem portion being inserted in an opening of a vial; wherein the stem portion is provided with a small diameter portion and a seal portion, in that order from the lower surface the head portion, the diameter of the small diameter portion being smaller than the diameter of the seal portion. The entirety of the small diameter portion and the seal portion are substantially uniformly fitted in the opening of the vial.

Abstract: A sealing rubber closure is provided for use with a syringe/container specified by ISO (the International Organization of Standardization) and having a Luer nozzle to be inserted into a Luer-nozzle-receiving part of the sealing rubber closure. The Luer-nozzle-receiving part is configured, on a side of an inner end portion thereof, in an untapered cylindrical form to assure tight-fitted insertion of a free end portion of the Luer nozzle and, on a side of a Luer-nozzle-receiving opening thereof, in a tapered, substantially cylindrical form to assure tight-fitted insertion of a basal end portion of the Luer nozzle. A plastic film is laminated on the sealing rubber closure at least in an area of the Luer-nozzle-receiving part, where a free end of the Luer nozzle is to be maintained in contact with the sealing rubber closure.

Abstract: A sealing rubber closure is provided for use with a syringe/container specified by ISO (the International Organization of Standardization) and having a Luer nozzle to be inserted into a Luer-nozzle-receiving part of the sealing rubber closure. The Luer-nozzle-receiving part is configured, on a side of an inner end portion thereof, in an untapered cylindrical form to assure tight-fitted insertion of a free end portion of the Luer nozzle and, on a side of a Luer-nozzle-receiving opening thereof, in a tapered, substantially cylindrical form to assure tight-fitted insertion of a basal end portion of the Luer nozzle. A plastic film is laminated on the sealing rubber closure at least in an area of the Luer-nozzle-receiving part, where a free end of the Luer nozzle is to be maintained in contact with the sealing rubber closure.

Abstract: A cylindrical vial having a bottom, for a medicine, in which an open end of the cylindrical vial is sealed by a needle-penetrable rubber closure through which a needle can be penetrated, the cylindrical vial including a conical bottom end provided opposite to the open end, wherein the apex of the conical bottom end is located on a central axis of the cylindrical vial at the bottommost point inside the cylindrical vial.

Abstract: A laminated rubber stopper having a new structure, capable of being produced in a simple process with a reduced production cost and being excellent in tightness, sealing property and sanitary property, is provided, comprising a top part having a flange part and a leg part provided under the top part of the rubber stopper and to be inserted into the mouth part of a vial, at least a surface thereof to be contacted with a contents in the vial being laminated with a fluoro resin film, in which the lower surface of the flange part has an annular concavity with a cross section of a circular arc from the periphery of the flange to the neck part.

Abstract: A sanitary container is molded from a plastic, for example, a cyclic olefin polymer or a hydrogenation product thereof. The plastic has been added with at least one pigment selected from the group consisting of C.I. Pigment Yellow 147, C.I. Pigment Yellow 180 and C.I. Pigment Yellow 181. The content of the at least one pigment may preferably range from 0.01 to 0.3 wt. % based the plastic.

Abstract: In a plunger for a syringe including a laminated piston which is provided with a shaft with a female thread and which is slidably inserted into a barrel and a rod having a male thread which can be screw-engaged in the threaded hole of the laminated piston, the axial length T of the crest of the female thread and the root of the male thread which engages with the female thread is greater than the axial length t of the root of the female thread and the crest of the male thread.

Abstract: A syringe is provided with a Luer-Lok portion for connecting an extension tube or the like. The Luer-Lok portion is arranged upright on a plane of truncation of a conical-frustum-shaped free end portion of the syringe, and includes an inner cylindrical portion and an outer cylindrical portion surrounding the inner cylindrical portion and having at least two projecting helical ribs formed in parallel with each other on an inner peripheral surface thereof. The extension tube or the like can be connected to the Luer-Lok portion by screwing at least two projecting helical ribs of a cylindrical connector, said at least two projecting helical ribs being formed in parallel with each other on an outer peripheral surface of the cylindrical connector, in corresponding grooves defined between the helical projecting ribs of the outer cylindrical portion.

Abstract: A plastic cap is provided which is capable of assuring a high sealing property and is advantageous for protection of the environment because of being readily subjectable to disposal of waste or burning treatment after using a container. The plastic cap comprises a drum part covering the mouth part of a container and sealing material and a top plate positioned on a top wall of the drum part, in which the drum part has, on the inner wall thereof, a protrusion part or wedge-shaped part to be engaged with an annular protrusion on the outer periphery of the container mouth part. A window part opens at the center part of the top wall of the cap drum port, and the outer edge of the window part and the lower part of the top plate are connected through several bridged parts.

Abstract: A medical instrument capable of maintaining medicament liquids such as pharmaceuticals, nutriments in high quality and dosing correctly and sanitarily is provided. This medical instrument comprises a material containing a resin formed of a cyclic olefin compound or a bridged polycyclic hydrocarbon compound, as a polymeric component.

Abstract: There is provided a rubber composition and a rubber article for pharmaceutical chemicals or medical treatments, obtained by forming and cross-linking this rubber composition, the rubber article having very excellent properties which can be adapted to the standard test values of various official documents, required in this field, and can further satisfy the test items having lately become an important problem from the pharmaceutical standpoint. This rubber composition comprises 0.3 to 3.5 parts by weight of an organic peroxide cross-linking agent, 0.3 to 4 parts by weight of an organic compound having at least 2 maleimide groups in one molecule and optionally, 0.6 to 30 parts by weight of an organosilicone compound per 100 parts by weight of a isobutylene-isoprene copolymer rubber.

Abstract: An adaptor system includes a plastic syringe which is pre-filled with a liquid medicament, and a plastic flange adaptor which can be attached to the syringe. The medicament-prefilled syringe is provided with a cylindrical body having a small diameter cylindrical body to which a liquid medicament information label is adhered and a large diameter cylindrical body, and an end flange. The flange adaptor is provided with a cylindrical base portion having an insertion hole whose diameter is such that the inner wall of the insertion hole does not contact the small diameter cylindrical body of the syringe and is in contact with the large diameter cylindrical body when the flange adaptor is fitted to the syringe, and a large diameter flange portion which surrounds the end flange of the syringe. The invention is also directed to a medicament-prefilled plastic syringe itself.

Abstract: A sliding piston for a syringe, which is inserted in a hollow barrel of a syringe is made of a substantially cylindrical body having a shape symmetrically rotatable with respect to the axis of the hollow barrel. The cylindrical body has its largest diameter at the front end thereof. The peripheral edge of the front end of the cylindrical body is rounded at a radius of curvature of 5/100 mm to 10/100 mm. The diameter of the rear end of the cylindrical body is smaller than the inner diameter of the hollow barrel so as not to contact with the inner surface of the hollow barrel when the piston is inserted in the hollow barrel.

Abstract: A sanitary rubber article coated with a film composed of a siloxane composition comprising the following Component A and the following Component B, Component B being present in a proportion of 0.1 to 5 parts by weight to 100 parts by weight of Component A:Component Aat least one organosiloxane having a recurring unit represented by the following General Formula (I): ##STR1## Component B at least one of organopolysiloxanes having a recurring unit represented by the following General Formula (II): ##STR2## wherein R.sub.1 to R.sub.5, n, x and y are defined in the specification.

Abstract: A sanitary container is composed of a base container made of a cyclic olefin polymer or its hydrogenation product and an inorganic coating formed on a surface of said base container. The sanitary container can be produced by forming the inorganic coating on the surface of the base container by plasma CVD.

Abstract: A rubber plug for a drug vessel has at least one convexity formed on a surface of the rubber plug so that the rubber plug is prevented from sticking together, joining together under compression or joining together under suction with another rubber plug of a similar type. The convexity may preferably be a grain pattern formed on at least a part of the surface of the rubber plug by transferring same from a mold. A rubber plug for a drug vessel may also be composed of a leg portion and a head portion formed integrally with the leg portion and may have at least one convexity on at least one of the leg portion and the head portion.