Abstract: The present invention is directed to a pneumatic tire comprising a tread portion having (i) circumferential grooves and (ii) circumferential ribs or rows of tread blocks; an inner surface defining a tire cavity; and a sealant material layer at least partially covering the inner surface radially below the tread portion within the tire cavity. The sealant material layer comprises elevations of sealant material, wherein an elevation of sealant material is provided radially below each of at least two of the circumferential grooves, and wherein the sealant material layer has a larger radial thickness in said elevations than in areas radially below the circumferential ribs or rows of tread blocks.