Abstract: Methods and compositions for preparing and priming a tissue graft for an accelerated therapeutic effect are provided herein. In one embodiment, the method includes obtaining a tissue containing viable cells from a donor, wherein the viable cells are endogenous to the tissue and remain resident in the tissue; and priming the viable cells with one or more stimuli comprising simulated hypoxia to produce a primed tissue, wherein when grafted to a recipient the primed tissue provides a benefit compared to non-primed tissue.

Abstract: Methods and compositions for preparing and priming a tissue graft for an accelerated therapeutic effect are provided herein. In one embodiment, the method includes obtaining a tissue containing viable cells from a donor, wherein the viable cells are endogenous to the tissue and remain resident in the tissue; and priming the viable cells with one or more stimuli comprising simulated hypoxia to produce a primed tissue, wherein when grafted to a recipient the primed tissue provides a benefit compared to non-primed tissue.

Abstract: Methods and compositions for preparing and priming a tissue graft for an accelerated therapeutic effect are provided herein. In one embodiment, the method includes obtaining a tissue containing viable cells from a donor, wherein the viable cells are endogenous to the tissue and remain resident in the tissue; and priming the viable cells with one or more stimuli to produce a primed tissue, wherein when grafted to a recipient the primed tissue provides a benefit compared to non-primed tissue.

Abstract: A medical implant packaging assembly having an outer tray, an inner tray and a retainer. An implant which may include a hydrated tissue graft may be positioned within the packaging assembly. The inner tray is formed from a moisture barrier material whereby the implant may be maintained in a hydrated state, even if the implant is not immersed in fluid within the packaging assembly, thereby avoiding need for rehydrating steps that are required for dehydrated and/or cryopreserved implants prior to or during surgery. The outer tray and inner tray and a retainer are also made of transparent materials, enabling medical personnel to view the implant through these packaging components prior to and during surgery.

Abstract: A medical implant packaging assembly having an outer tray, an inner tray and a retainer. An implant which may include a hydrated tissue graft may be positioned within the packaging assembly. The inner tray is formed from a moisture barrier material whereby the implant may be maintained in a hydrated state, even if the implant is not immersed in fluid within the packaging assembly, thereby avoiding need for rehydrating steps that are required for dehydrated and/or cryopreserved implants prior to or during surgery. The outer tray and inner tray and a retainer are also made of transparent materials, enabling medical personnel to view the implant through these packaging components prior to and during surgery.

Abstract: A medical implant packaging assembly having an outer tray, an inner tray and a retainer The implant may include a tissue graft. The inner tray is formed from a moisture barrier material whereby the implant may be maintained in a hydrated state, thereby avoiding need for rehydrating steps that are required for dehydrated or cryopreserved implants. The outer tray and inner tray and a retainer are also made of transparent materials, enabling medical personnel to view the implant through these packaging components prior to and during surgery.

Abstract: A medical implant packaging assembly having an outer tray, an inner tray and a retainer The implant may include a tissue graft. The inner tray is formed from a moisture barrier material whereby the implant may be maintained in a hydrated state, thereby avoiding need for rehydrating steps that are required for dehydrated or cryopreserved implants. The outer tray and inner tray and a retainer are also made of transparent materials, enabling medical personnel to view the implant through these packaging components prior to and during surgery.