Patents by Inventor Morris Zimmerman

Morris Zimmerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cephalosporin derivatives as anti-inflammatory agents
    Patent number: 4891370
    Abstract: Derivatives of cephalosporin esters are found to be potent elastase inhibitors and therefore are useful antiinflammatory agents.
    Type: Grant
    Filed: December 14, 1981
    Date of Patent: January 2, 1990
    Assignee: Merck & Co., Inc.
    Inventors: Morris Zimmerman, Bunnie M. Ashe, James B. Doherty
  • .beta.-Lactam derivatives as anti-inflammatory and antidegenerative agents
    Patent number: 4797396
    Abstract: .beta.-Lactam derivatives and analogs are found to be potent elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.
    Type: Grant
    Filed: July 16, 1987
    Date of Patent: January 10, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Paul E. Finke, Morris Zimmerman, James B. Doherty, Bonnie M. Ashe, Conrad P. Dorn
  • .beta.-lactam derivatives as anti-inflammatory and antidegenerative agents
    Patent number: 4711886
    Abstract: .beta.-Lactam derivatives and analogs are found to be potent elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.
    Type: Grant
    Filed: July 2, 1984
    Date of Patent: December 8, 1987
    Assignee: Merck & Co., Inc.
    Inventors: Paul E. Finke, James B. Doherty, Morris Zimmerman, Bonnie M. Ashe, Conrad P. Dorn
  • Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
    Patent number: 4623645
    Abstract: Substituted cephalosporin sulfoxides are found to be potent elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.
    Type: Grant
    Filed: April 18, 1983
    Date of Patent: November 18, 1986
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, Bonnie M. Ashe, Paul E. Finke, Raymond A. Firestone, Shrenik K. Shah, Morris Zimmerman
  • Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
    Patent number: 4547371
    Abstract: Substituted cephalosporin sulfones are found to be potent elastase inhibitors and thereby useful anti-inflammatory/antidegenerative agents.
    Type: Grant
    Filed: April 18, 1983
    Date of Patent: October 15, 1985
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, Bonnie M. Ashe, Paul E. Finke, Shrenik K. Shah, Kevan R. Thompson, Morris Zimmerman
  • N-Carboxyl-thienamycin esters and analogs thereof as anti-inflammatory agents
    Patent number: 4495197
    Abstract: Derivatives of N-carboxyl-thienamycin esters and analogs thereof are found to be potent elastase inhibitors and thereby useful anti-inflammatory agents.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: January 22, 1985
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, Morris Zimmerman, Bonnie M. Ashe
  • 1-Carbapenem-3-carboxylic esters as anti-inflammatory agents
    Patent number: 4493839
    Abstract: Derivatives of 1-carbapenem-3-carboxylic esters are found to be potent elastase inhibitors and therefore are useful anti-inflammatory agents.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: January 15, 1985
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, Morris Zimmerman, Bonnie M. Ashe
  • Thienamycin derivatives as anti-inflammatory agents
    Patent number: 4465687
    Abstract: N-acyl-derivatives of thienamycin esters are found to be potent elastase inhibitors and therefore are useful anti-inflammatory agents.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: August 14, 1984
    Assignee: Merck & Co., Inc.
    Inventors: James B. Doherty, Morris Zimmerman, Bonnie M. Ashe
  • 2-Pyridyl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors
    Patent number: 4369183
    Abstract: The invention concerns novel 2-aryl-1,2-benzisothiazolinone-1,1-dioxide compounds; methods for their preparation; pharmaceutical compositions containing them as an active ingredient; and methods of selectively inhibiting proteases, especially elastase, and of treating emphysema, rheumatoid arthritis, and various inflammatory diseases, for example, bronchial inflammation.
    Type: Grant
    Filed: February 2, 1981
    Date of Patent: January 18, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Howard Jones, Robert L. Clark, Morris Zimmerman
  • 2-Aryl-1,2-benzisothiazolinone-1,1-dioxides and their use as selective protease inhibitors
    Patent number: 4276298
    Abstract: The invention concerns novel 2-aryl-1,2-benzisothiazolinone-1,1-dioxide compounds; methods for their preparation; pharmaceutical compositions containing them as an active ingredient; and methods of inhibiting proteases, especially elastase, and of treating emphysema, rheumatoid arthritis, and various inflammatory diseases, for example, bronchial inflammation.
    Type: Grant
    Filed: September 6, 1979
    Date of Patent: June 30, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Howard Jones, Robert L. Clark, Morris Zimmerman
  • 2-(2-Furoyl)1,2-benzisothiazole-3-one, 2-(2-furoyl) saccharin, and 2-(2-thenoyl) saccharin
    Patent number: 4195023
    Abstract: Certain novel acyl saccharins and acyl 3-oxo-1,2-benzisothiazolines, their preparation, pharmaceutical compositions and novel methods of inhibiting elatase and treating emphysema are disclosed.
    Type: Grant
    Filed: August 20, 1975
    Date of Patent: March 25, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Dennis Mulvey, Howard Jones, Morris Zimmerman