Patents by Inventor Morten Borch

Morten Borch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200393478
    Abstract: Provided are methods and apparatuses for controlling a position of a target point on a processing result relative to a focus point of a focusing sensor system for determining properties of the processing result. The method includes the steps of determining an initial focus point of the focusing sensor system, controlling rotation of the cartridge and disc, checking whether the initial focus point of the focusing sensor system corresponds to the target point on the processing result, comparing (x, y) target positions in captured images with the initial focus point of the focusing sensor system, adjusting rotation of the cartridge and disc such that the focus point of the focusing sensor system corresponds to the target point on the processing result, and detecting and examining signals received from the focusing sensor system for determining properties of the processing result.
    Type: Application
    Filed: November 5, 2018
    Publication date: December 17, 2020
    Applicant: SpinChip Diagnostics AS
    Inventors: Ole Christian TRONRUD, Rolf JAHREN, Sebastian STENMARK, Stig Morten BORCH
  • Publication number: 20200391227
    Abstract: Provided is a centrifuge apparatus for a processing cartridge, including a rotary plate and at least one cartridge holder, and the cartridge holder is rotatable around its centre axis and arranged off-centre the centre axis of the rotary plate and comprises an inner side wall surrounding a through-going passage, wherein the through-going passage is able to accommodate the processing cartridge; and the inner side wall includes a resilient locking assembly for interaction with at least one cooperating first abutting surface on the processing cartridge, such that the processing cartridge may be inserted into the through-going passage and releasably secured by the locking assembly; and at least one stopping element for interaction with at least one cooperating second abutting surface on the processing cartridge, the at least one stopping element being arranged to retain the processing cartridge at a desired vertical level when the cartridge is releasably secured.
    Type: Application
    Filed: September 20, 2018
    Publication date: December 17, 2020
    Applicant: SpinChip Diagnostics AS
    Inventors: Ole Christian TRONRUD, Sebastian STENMARK, Rolf JAHREN, Torgeir HAMSUND, Stig Morten BORCH
  • Patent number: 10408713
    Abstract: The present invention provides a method of analyzing a sample containing an analyte to be qualitatively and/or quantitatively determined, comprising a binding step and a washing step, wherein the binding step comprises: interacting the analyte with beads having a density m1; obtaining a structure of packed beads comprising quantifiable bead complexes having a density m2; and the washing step comprises: dispersing the packed beads in a liquid medium having a density d>m2 and m1; and separating the liquid medium and the beads comprising the quantifiable bead complexes.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: September 10, 2019
    Assignee: SpinChip Diagnostics AS
    Inventors: Stig Morten Borch, Torgeir Hamsund, Jostein Geir Holtlund, Anja Gulliksen
  • Patent number: 10228308
    Abstract: A method for transferring beads in a fluidic chip having an internal fluid circuit through which various reactants, including beads, may be moved by use of centrifugal force includes providing beads having a density equal to, or lower than, m1 in a section of the fluid circuit, where the section includes at least a first outlet. The method includes providing a first liquid medium having a density d2 to the section, such that d2>m1, and applying a centrifugal force such that the beads migrate in an opposite direction of the centrifugal force.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: March 12, 2019
    Assignee: SpinChip Diagnostics AS
    Inventors: Stig Morten Borch, Torgeir Hamsund, Jostein Geir Holtlund, Anja Gulliksen
  • Publication number: 20180143183
    Abstract: The present invention provides an assay method for a cell-containing body sample, said method comprising treating said sample under conditions whereby to cause cell lysis, preferably by means of a detergent; and subjecting the thus-generated lysed sample to conditions causing the cleavage of nucleic acid molecules. The invention additionally provides the use of nucleic acid cleavage conditions in enhancing a membrane assay, a device for carrying out such an assay, and a kit for use in the assay.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 24, 2018
    Inventors: Jostein HOLTLUND, Andrew CAMPBELL, Morten BORCH
  • Patent number: 9927328
    Abstract: The present invention provides a method of separating beads in a fluidic chip comprising an internal fluid circuit through which various reactants, in which at least one of the reactants are beads, may be moved by use of centrifugal force, the method comprises the steps of: providing at least a first set of beads (8a) having a density m1 and a second set of beads (8b) having a density m2 in a section (7, 15, 18) of the fluid circuit, the section comprising at least a first outlet (16, 13, 17); providing a first liquid medium in the section, the liquid medium having a density d3, such that m1<d3<m2; and applying a first centrifugal force (G) such that the first set of beads (8a) and the second set of beads (8b) migrates in opposite directions within the section.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: March 27, 2018
    Assignee: SpinChip Diagnostics AS
    Inventors: Stig Morten Borch, Torgeir Hamsund, Jostein Geir Holtlund, Anja Gulliksen
  • Patent number: 9897594
    Abstract: The present invention provides an assay method for a cell-containing body sample, the method comprising treating the sample under conditions whereby to cause cell lysis, preferably by means of a detergent; and subjecting the thus-generated lysed sample to conditions causing the cleavage of nucleic acid molecules. The invention additionally provides the use of nucleic acid cleavage conditions in enhancing a membrane assay, a device for carrying out such an assay, and a kit for use in the assay.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: February 20, 2018
    Assignee: AXIS-SHIELD ASA
    Inventors: Jostein Holtlund, Andrew Campbell, Morten Borch
  • Publication number: 20170138938
    Abstract: The present invention provides a method of analyzing a sample containing an analyte to be qualitatively and/or quantitatively determined, comprising a binding step and a washing step, wherein the binding step comprises: interacting the analyte with beads having a density m1; obtaining a structure of packed beads comprising quantifiable bead complexes having a density m2; and the washing step comprises: dispersing the packed beads in a liquid medium having a density d>m2 and m1; and separating the liquid medium and the beads comprising the quantifiable bead complexes.
    Type: Application
    Filed: June 19, 2015
    Publication date: May 18, 2017
    Applicant: SpinChip Diagnostics AS
    Inventors: Stig Morten BORCH, Torgeir HAMSUND, Jostein Geir HOLTLUND, Anja GULLIKSEN
  • Publication number: 20170138823
    Abstract: The present invention provides a method of separating beads in a fluidic chip comprising an internal fluid circuit through which various reactants, in which at least one of the reactants are beads, may be moved by use of centrifugal force, the method comprises the steps of: providing at least a first set of beads (8a) having a density m1 and a second set of beads (8b) having a density m2 in a section (7, 15, 18) of the fluid circuit, the section comprising at least a first outlet (16, 13, 17); providing a first liquid medium in the section, the liquid medium having a density d3, such that m1<d3<m2; and applying a first centrifugal force (G) such that the first set of beads (8a) and the second set of beads (8b) migrates in opposite directions within the section.
    Type: Application
    Filed: June 19, 2015
    Publication date: May 18, 2017
    Applicant: SpinChip Diagnostics AS
    Inventors: Stig Morten BORCH, Torgeir HAMSUND, Jostein Geir HOLTLUND, Anja GULLIKSEN
  • Publication number: 20170138939
    Abstract: The present invention provides a method of transferring beads in a fluidic chip comprising an internal fluid circuit through which various reactants, in which at least one of the reactants are beads, may be moved by use of centrifugal force, the method comprises the steps of: providing beads (8) having a density equal to, or lower than, m1 in a section (7, 15) of the fluid circuit, the section comprising at least a first outlet (16, 13); providing a first liquid medium to the section, the liquid medium having a density d2, such that d2>m1; and applying a centrifugal force such that the beads migrate in the opposite direction of the centrifugal force.
    Type: Application
    Filed: June 19, 2015
    Publication date: May 18, 2017
    Applicant: SpinChip Diagnostics AS
    Inventors: Stig Morten BORCH, Torgeir HAMSUND, Jostein Geir HOLTLUND, Anja GULLIKSEN
  • Patent number: 9162227
    Abstract: A sample processing cartridge for carrying out processing under centrifugal force acting in at least two directions as the orientation of cartridge relative to centrifugal force is changed, the cartridge comprising: a first cavity adapted to contain a sample; and a second cavity in fluid communication with the first cavity, wherein the first and second cavities are arranged such that the sample in the first cavity is moved therefrom to the second cavity as a centrifugal force acting on the cartridge is changed from a first direction to a second direction, the first cavity is elongated perpendicular to the centrifugal force acting in the first direction, and the second cavity is more shallow than the first cavity and more extended in the direction of the centrifugal force acting in the second direction than the first cavity is extended in the direction of the centrifugal force acting in the first direction.
    Type: Grant
    Filed: December 28, 2010
    Date of Patent: October 20, 2015
    Assignee: Stiftelsen Sintef
    Inventor: Stig Morten Borch
  • Patent number: 9140694
    Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: September 22, 2015
    Assignee: AXIS-SHIELD ASA
    Inventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Ton, Jan Roger Karlson, Inger Lise Lauvstad
  • Publication number: 20140065646
    Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.
    Type: Application
    Filed: August 29, 2013
    Publication date: March 6, 2014
    Applicant: Axis-Shield AS
    Inventors: Jostein HOLTLUND, Stig Morten BORCH, Thorstein SEIM, Tore JANSON, Hege TON, Jan Roger KARLSON, Inger Lise LAUVSTAD
  • Patent number: 8666201
    Abstract: This invention relates to an optical sensor element comprising a photonic crystal constituted by a membrane of a chosen transparent material, the membrane being provided with a number of defined openings in a chosen pattern, the pattern being adapted to provide resonance at a chosen wavelength or range of wavelengths, wherein said openings are provided with a reactive material acting as a receptor for a chosen type of molecules, e.g. proteins, the presence of which alters the resonance and/or scattering conditions in the sensor element thus altering the amount of light propagating out of the membrane plane.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: March 4, 2014
    Assignees: Sintef, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jon Olav Grepstad, Stig Morten Borch, Ib-Rune Johansen, Aasmund Sudbo, Olav Solgaard
  • Patent number: 8545756
    Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: October 1, 2013
    Assignee: Axis-Shield ASA
    Inventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
  • Publication number: 20130065256
    Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 14, 2013
    Applicant: AXIS-SHIELD AS
    Inventors: Jostein HOLTLUND, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
  • Publication number: 20120301972
    Abstract: The present invention relates to a centrifuge apparatus (10) comprising: a support member (12) rotatable about a first axis (20); at least one holding means (22) mounted to said support member for rotation therewith about the first axis, wherein each holding means is adapted to rotate about a respective second axis (24) distal to said first axis and to receive a sample processing device (26) for rotation thereof also about the second axis; a first motor (28a) adapted to rotate said support member about said first axis; and a second motor (28b) coupled to said at least one holding means; wherein the two motors (28a, 28b) are placed off the support member on opposite sides of the support member. The invention also relates to use of such an apparatus, and to a centrifugation method.
    Type: Application
    Filed: December 28, 2010
    Publication date: November 29, 2012
    Applicant: STIFTELSEN SINTEF
    Inventors: Stig Morten Borch, Esben Beck
  • Publication number: 20120282707
    Abstract: The present invention relates to a sample processing cartridge (10) for carrying out processing under centrifugal force acting in at least two directions as the orientation of cartridge relative to centrifugal force is changed, the cartridge comprising: a first cavity (18) adapted to contain a sample; and a second cavity (22) in fluid communication with the first cavity, wherein the first and second cavities are arranged such that the sample in the first cavity is moved therefrom to the second cavity as a centrifugal force acting on the cartridge is changed from a first direction (30) to a second direction (36), the first cavity is elongated perpendicular to the centrifugal force acting in the first direction, and the second cavity is more shallow than the first cavity and more extended in the direction of the centrifugal force acting in the second direction than the first cavity is extended in the direction of the centrifugal force acting in the first direction.
    Type: Application
    Filed: December 28, 2010
    Publication date: November 8, 2012
    Inventor: Stig Morten Borch
  • Patent number: 8293175
    Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to receive said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge or from said pipette.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: October 23, 2012
    Assignee: Axis-Shield ASA
    Inventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
  • Publication number: 20120002913
    Abstract: This invention relates to an optical sensor element comprising a photonic crystal constituted by a membrane of a chosen transparent material, the membrane being provided with a number of defined openings in a chosen pattern, the pattern being adapted to provide resonance at a chosen wavelength or range of wavelengths, wherein said openings are provided with a reactive material acting as a receptor for a chosen type of molecules, e.g. proteins, the presence of which alters the resonance and/or scattering conditions in the sensor element thus altering the amount of light propagating out of the membrane plane.
    Type: Application
    Filed: March 24, 2010
    Publication date: January 5, 2012
    Applicant: SINTEF
    Inventors: Jon Olav Grepstad, Stig Morten Borch, Ib-Rune Johansen, Aasmund Sudbo, Olav Solgaard