Abstract: The compound 4-[2,3-Difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine according to the structure (formula I), and pharmaceutically acceptable salts thereof are provided for the treatment of CNS related disorders, such as: depressive disorder, dysthymic disorder; mood disorder due to a general medical condition; atypical depression; seasonal affective disorder; melancholia; treatment resistant depression; partial responders; depression associated with bipolar disorder, pain, Alzheimer's disease, psychosis, Parkinson's disease, Lewy body disease, Huntington's disease, multiple sclerosis or anxiety; general anxiety disorder, social anxiety disorder, panic attacks; phobia; social phobia, obsessive compulsive disorder; post traumatic stress disorder, acute stress; ADHD; and pain.

Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT3 and 5-HT1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.

Abstract: A sound system design/simulation system includes background noise to provide more realistic sound renderings of the designed space and more accurate quality measures of the design space. The background noise may be provided as a library in the design system that allows the user to select a background noise profile. The user may also provide a recording of a background noise from the built space or from a similar space. The design system converts the recorded background noise to a background noise profile and adds the profile to the library of background noise profiles. The user can select a background noise profile and associate the profile with a specified space. The user can adjust the noise level of the background noise and the design system automatically updates one or more quality measures in response to the change in background noise level.

Abstract: A device for plasma treating a surface comprises a movable plasma generator and an actuator for moving the plasma generator. The actuator may be configured to move the plasma generator in a first direction along a path and then in a second direction along substantially the same path (e.g. the same path, an ovular path, etc.). For example, the actuator may be configured to reciprocate the plasma generator back and forth along the path. Movement of the plasma generator may be made along a track. To facilitate movement along the track, the plasma generator may include bearings that cooperate with the track. The plasma generator may be configured to move from a first position to a second position through an intermediate position. The plasma generator may then be configured to move back towards the first position by traveling through the intermediate, or substantially the intermediate, position.

Abstract: The invention provides compounds represented by the general formula (I) wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.

Abstract: The invention is directed to a display and method for conducting sound system design. The display is configured to simultaneously show a sound system model comprising both audio components and sound environment components, a plurality of parameters and a graphic representation of a calculated sound system performance attribute. In response to receiving input from the user and without any additional user intervention, the display re-displays a newly-calculated sound system performance attribute such as, for example, a graphic representation in the sound system model of a sound path associated with a user-selected reflected sound identifier. A processor also simulates, based on the sound system configuration, the sound performance that a user would expect to hear positioned in an identified listening position of the sound system model.

Abstract: The invention is directed to a display and method for conducting sound system design. The display is configured to simultaneously show a sound system model comprising both audio components and sound environment components, a plurality of parameters and a graphic representation of a calculated sound system performance attribute. In response to receiving input from the user and without any additional user intervention, the display re-displays a newly-calculated sound system performance attribute such as, for example, a graphic representation in the sound system model of a sound path associated with a user-selected reflected sound identifier. A processor also simulates, based on the sound system configuration, the sound performance that a user would expect to hear positioned in an identified listening position of the sound system model.

Abstract: The present invention relates to novel phenolic and catecholic amines of Formula I, to processes for their preparation, pharmaceutical compositions containing them, to their use in therapy and to their use in radiolabeled form as PET- or SPECT ligands.

Abstract: A sound system design/simulation system provides a more realistic simulation of an existing venue by matching a measured reverberation characteristic of the existing venue and adjusting one or more acoustic parameters characterizing the model such that a predicted reverberation characteristic substantially matches the measured reverberation characteristic.

Abstract: A vortex generator uses a single piece to generate the vortex and hold the electrode. The single piece may be a non-conductive material such as a ceramic. The vortex generator may use threads to hold the electrode. The threads and holes for generating the vortex may be bored into the base material of the vortex generator before the base material is hardened.

Abstract: A sound system design/simulation system includes background noise to provide more realistic sound renderings of the designed space and more accurate quality measures of the design space. The background noise may be provided as a library in the design system that allows the user to select a background noise profile. The user may also provide a recording of a background noise from the built space or from a similar space. The design system converts the recorded background noise to a background noise profile and adds the profile to the library of background noise profiles. The user can select a background noise profile and associate the profile with a specified space. The user can adjust the noise level of the background noise and the design system automatically updates one or more quality measures in response to the change in background noise level.

Abstract: The present invention relates to novel catecholamine derivatives of Formula I, to processes for their preparation, pharmaceutical compositions containing them and to their use in therapy.

Abstract: The present invention relates to novel catecholamine derivatives of Formula I, to processes for their preparation, pharmaceutical compositions containing them and to their use in therapy.

Abstract: A vortex generator uses a single piece to generate the vortex and hold the electrode. The single piece may be a non-conductive material such as a ceramic. The vortex generator may use threads to hold the electrode. The threads and the means for generating the vortex may be bored into the base material of the vortex generator before the base material is hardened.

Abstract: A device for plasma treating a surface comprises a movable plasma generator and an actuator for moving the plasma generator. The actuator may be configured to move the plasma generator in a first direction along a path and then in a second direction along substantially the same path (e.g. the same path, an ovular path, etc.). For example, the actuator may be configured to reciprocate the plasma generator back and forth along the path. Movement of the plasma generator may be made along a track. To facilitate movement along the track, the plasma generator may include bearings that cooperate with the track. The plasma generator may be configured to move from a first position to a second position through an intermediate position. The plasma generator may then be configured to move back towards the first position by traveling through the intermediate, or substantially the intermediate, position.

Abstract: The invention provides compounds represented by the general formula (I) wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.

Abstract: A line array loudspeaker, including a first plurality of acoustic drivers each acoustic driver comprising an axis, the first plurality of acoustic drivers arranged so that the axes of first plurality of acoustic drivers are coplanar in a first plane and so that a straight line intersects each axis at a same position on each of the first plurality of acoustic drivers, and a second plurality of acoustic drivers each acoustic driver comprising an axis, the second plurality of acoustic drivers arranged so that the axes of second plurality of acoustic drivers are coplanar in a second plane and so that the straight line intersects each axis at a same position on each of the second plurality of acoustic drivers, in which the first plurality and the second plurality arranged so that the first plane intersects with the second plane along a straight intersection line.

Abstract: A conveyor system for exposing an object to an electrical discharge to increase the surface tension of a surface of the object comprises a guide, a first conveyor, an electrode, and a second conveyor. The first conveyor is configured to convey the object toward the guide. The electrode is configured to provide an electrical discharge. The guide and the second conveyor are configured to rotate the object for exposure to the electrical discharge.

Abstract: Methods and systems are configured to expose an object to an electrical discharge. The system includes a conveyor that conveys the object, a guide that guides the object, and an electrode that provides an electrical discharge. The guide is typically set to guide the object laterally with respect to the direction of the conveyor. The guide is generally used to place an object at a predetermined distance from the electrode. Also, the system may include multiple electrodes. The plural electrodes may be used to treat multiple sides of the object. Also, the electrodes may be positioned such that they are not coplanar with the conveyor. The system is suitably used to treat hollow objects which are in filling positions.

Abstract: A conveyor system for exposing an object to an electrical discharge to increase the surface tension of a surface of the object comprises a guide, a first conveyor, an electrode, and a second conveyor. The first conveyor is configured to convey the object toward the guide. The electrode is configured to provide an electrical discharge. The guide and the second conveyor are configured to rotate the object for exposure to the electrical discharge.