Patents by Inventor Morten Schlein

Morten Schlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MIXTURE COMPRISING AN AMYLIN PEPTIDE AND A PROTRACTED INSULIN
    Publication number: 20100222251
    Abstract: The invention relates to a soluble pharmaceutical composition for parenteral administration, which comprises an amylin peptide and a protracted insulin peptide.
    Type: Application
    Filed: September 11, 2008
    Publication date: September 2, 2010
    Applicant: Novo Nordisk A/S
    Inventor: Morten Schlein
  • Stable Formulations of Peptides
    Publication number: 20100190715
    Abstract: Method for increasing the shelf-life of a pharmaceutical formulation comprising a glucagon-like peptide.
    Type: Application
    Filed: April 1, 2010
    Publication date: July 29, 2010
    Applicant: Novo Nordisk A/S
    Inventors: Morten Schlein, Svend Ludvigsen
  • Stable Formulations of Peptides
    Publication number: 20100173844
    Abstract: Stable pharmaceutical composition comprising insulinotropic peptide.
    Type: Application
    Filed: December 21, 2009
    Publication date: July 8, 2010
    Applicant: Novo Nordisk A/S
    Inventors: Svend Ludvigsen, Morten Schlein, Tine Elisabeth Gottschalk Boving, Claude Bonde, Anne-Mette Lilleore, Dorthe Kot Engelund, Bjarne Ronfeldt Nielsen
  • Soluble Pharmaceutical Compositions for Parenteral Administration Comprising a GLP-1 Peptide and an Insulin Peptide of Short Time Action for Treatment of Diabetes and Bulimia
    Publication number: 20090286716
    Abstract: Pharmaceutical composition for parenteral administration comprising a meal related insulin peptide and an insulinotropic peptide.
    Type: Application
    Filed: May 12, 2009
    Publication date: November 19, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudsen, Kristian Tage Hansen, Dorthe Kot Engelund, Svend Ludvigsen, Lars Hansen, Claude Bonde, Ejvind Jensen, Tine Elisabeth Gottschalk Boving, Morten Schlein
  • Single-Chain Insulin
    Publication number: 20090170750
    Abstract: The present invention is related to single-chain insulin having insulin activity comprising a B- and an A-chain or a modified B- and A-chain connected by a connecting peptide of from 6-11 amino acids. The single-chain insulins will have biological insulin activity and an IGF-1 receptor affinity similar to or lower than that of human insulin and a high physical stability. The single-chain insulin may contain at least one basic amino acid residues in the connecting peptide. The single-chain insulins may also be acylated in one or more Lys residues.
    Type: Application
    Filed: October 15, 2008
    Publication date: July 2, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Thomas Borglum Kjeldsen, Asser Sloth Andersen, Morten Schlein, Anders Robert Sorensen, Peter Madsen
  • Mixtures of Amylin and Insulin
    Publication number: 20090054305
    Abstract: The present invention relates to a soluble pharmaceutical composition for parenteral administration, which comprises an amylin peptide, and a meal-related insulin peptide, and to the use of such compositions for treatment of e.g. hyperglycemia.
    Type: Application
    Filed: March 15, 2007
    Publication date: February 26, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Morten Schlein, Thomas Kruse Hansen, Jesper Lau, Svend Ludvigsen
  • Stable Formulations Of Peptides
    Publication number: 20090011976
    Abstract: Stable pharmaceutical composition comprising insulinotropic peptide and basal insulin.
    Type: Application
    Filed: November 11, 2005
    Publication date: January 8, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Svend Ludvigsen, Morten Schlein, Tine Elisabeth Boving
  • Pharmaceutical Compositions Containing Insulin and Insulinotropic Peptide
    Publication number: 20080280814
    Abstract: Pharmaceutical composition for parenteral administration comprising insulin peptide an insulinotropic peptide and a ligand for the Hisb10 anion site.
    Type: Application
    Filed: September 19, 2005
    Publication date: November 13, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Svend Ludvigsen, Morten Schlein
  • Single-chain insulin
    Publication number: 20070129284
    Abstract: The present invention is related to single-chain insulin having insulin activity comprising a B- and an A-chain or a modified B- and A-chain connected by a connecting peptide of from 6-11 amino acids. The single-chain insulins will have biological insulin activity and an IGF-1 receptor affinity similar to or lower than that of human insulin and a high physical stability. The single-chain insulin may contain at least one basic amino acid residues in the connecting peptide. The single-chain insulins may also be acylated in one or more Lys residues.
    Type: Application
    Filed: May 24, 2006
    Publication date: June 7, 2007
    Applicant: Novo Nordisk A/S
    Inventors: Thomas Kjeldsen, Asser Andersen, Morten Schlein, Anders Sorensen, Peter Madsen
  • Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
    Publication number: 20060287221
    Abstract: Pharmaceutical composition for parenteral administration comprising a meal related insulin peptide and an insulinotropic peptide.
    Type: Application
    Filed: May 3, 2006
    Publication date: December 21, 2006
    Applicant: Novo Nordisk A/S
    Inventors: Liselotte Knudsen, Kristian Hansen, Dorthe Engelund, Svend Ludvigsen, Lars Hansen, Claude Bonde, Ejvind Jensen, Tine Elisabeth Boving, Morten Schlein
  • Stable formulations of peptides
    Publication number: 20060247167
    Abstract: Method for increasing the shelf-life of a pharmaceutical formulation comprising a glucagon-like peptide.
    Type: Application
    Filed: March 1, 2006
    Publication date: November 2, 2006
    Applicant: Novo Nordisk A/S
    Inventors: Morten Schlein, Svend Ludvigsen
  • Stabilised insulin compositions
    Publication number: 20050065066
    Abstract: The present invention provides pharmaceutical compositions comprising insulin and novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer. The resulting preparations have improved physical and chemical stability.
    Type: Application
    Filed: April 16, 2004
    Publication date: March 24, 2005
    Inventors: Niels Kaarsholm, Peter Madsen, Morten Schlein, Helle Olsen, Svend Havelund, Dorte Steensgaard, Svend Ludvigsen, Palle Jakobsen, Anders Petersen, Gerd Schluckebier
  • GLP-2 compounds, formulations, and uses thereof
    Publication number: 20040122210
    Abstract: The present invention relates to novel human glucagon-like peptide-2 (GLP-2) peptides and human glucagon-like peptide-2 derivatives which have a protracted profile of action as well as polynucleotide constructs encoding such peptides, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of treatment.
    Type: Application
    Filed: October 14, 2003
    Publication date: June 24, 2004
    Inventors: Lars Thim, Susanne Bang, Morten Schlein, Niels Christian Kaarsholm, Dorthe Kot Engelund, Anette Sams Nielsen, Nils Langeland Johansen, Kjeld Madsen, Magali Zundel, Peter Thygesen