Patents by Inventor Morten Østergaard JENSEN

Morten Østergaard JENSEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LACTAM COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
    Publication number: 20230373952
    Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, where the substituents are as defined herein. Pharmaceutical compositions including the same and method of using the same are also described.
    Type: Application
    Filed: October 4, 2021
    Publication date: November 23, 2023
    Inventors: Fabrizio GIORDANETTO, Morten Østergaard JENSEN, Vishwanath JOGINI, Roger John SNOW
  • ARYLMETHYLENE AROMATIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
    Publication number: 20230131535
    Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.
    Type: Application
    Filed: October 6, 2020
    Publication date: April 27, 2023
    Inventors: Fabrizio GIORDANETTO, Morten Østergaard JENSEN, Vishwanath JOGINI, Roger John SNOW
  • ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
    Publication number: 20230049231
    Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, where the substituents are as defined herein. Pharmaceutical compositions including the same and method of using the same are also described.
    Type: Application
    Filed: October 6, 2020
    Publication date: February 16, 2023
    Inventors: Fabrizio GIORDANETTO, Morten Østergaard JENSEN, Vishwanath JOGINI, Roger John SNOW
  • ARYL HETEROBICYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
    Publication number: 20230040182
    Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, where the substituents are as defined herein. Pharmaceutical compositions including the same and method of using the same are also described.
    Type: Application
    Filed: October 6, 2020
    Publication date: February 9, 2023
    Inventors: Fabrizio GIORDANETTO, Morten Østergaard JENSEN, Vishwanath JOGINI, Roger John SNOW
  • ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
    Publication number: 20230023559
    Abstract: A compound of Formula (I) or a pharmaceutically acceptable salt thereof is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.
    Type: Application
    Filed: October 6, 2020
    Publication date: January 26, 2023
    Applicants: D. E. Shaw Research, LLC, D. E. Shaw Research, LLC
    Inventors: Fabrizio GIORDANETTO, Morten Østergaard JENSEN, Vishwanath JOGINI, Roger John SNOW
  • ARYL HETEROCYCLIC COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
    Publication number: 20230026611
    Abstract: A compound of Formula (I), or a pharmaceutically-acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.
    Type: Application
    Filed: October 6, 2020
    Publication date: January 26, 2023
    Inventors: Fabrizio GIORDANETTO, Morten Østergaard JENSEN, Vishwanath JOGINI, Roger John SNOW
  • ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS
    Publication number: 20220411367
    Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.
    Type: Application
    Filed: October 6, 2020
    Publication date: December 29, 2022
    Inventors: Fabrizio GIORDANETTO, Morten Østergaard JENSEN, Vishwanath JOGINI, Roger John SNOW
  • Methods for screening voltage-gated proteins
    Patent number: 10753947
    Abstract: In one aspect, the invention relates to a method for identifying a compound which modulates the activity of a voltage-gated protein. In certain embodiments, the voltage gate protein is a voltage-gated ion channel. In certain embodiments, the voltage-gated protein is a voltage sensitive phosphatase. In certain embodiments, the voltage-gated protein used in conjunction with the methods of the invention is modified to altered permeability or voltage sensitivity.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: August 25, 2020
    Assignee: D.E. SHAW RESEARCH, LLC
    Inventors: Morten Østergaard Jensen, David Wayne Borhani, Vishwanath Jogini
  • Methods for screening voltage-gated proteins
    Patent number: 10739354
    Abstract: In one aspect, the invention relates to a method for identifying a compound which modulates the activity of a voltage-gated protein. In certain embodiments, the voltage gate protein is a voltage-gated ion channel. In certain embodiments, the voltage-gated protein is a voltage sensitive phosphatase. In certain embodiments, the voltage-gated protein used in conjunction with the methods of the invention is modified to altered permeability or voltage sensitivity.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: August 11, 2020
    Assignee: D.E. SHAW RESEARCH, LLC
    Inventors: Morten Østergaard Jensen, David Wayne Borhani, Vishwanath Jogini
  • METHODS FOR SCREENING VOLTAGE-GATED PROTEINS
    Publication number: 20170115309
    Abstract: In one aspect, the invention relates to a method for identifying a compound which modulates the activity of a voltage-gated protein. In certain embodiments, the voltage gate protein is a voltage-gated ion channel. In certain embodiments, the voltage-gated protein is a voltage sensitive phosphatase. In certain embodiments, the voltage-gated protein used in conjunction with the methods of the invention is modified to altered permeability or voltage sensitivity.
    Type: Application
    Filed: October 17, 2016
    Publication date: April 27, 2017
    Inventors: Morten Østergaard JENSEN, David Wayne BORHANI, Vishwanath JOGINI