Patents by Inventor Morteza Gharib

Morteza Gharib has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190106206
    Abstract: An automated flying transport vehicle that capitalizes on the strengths and complexities of a fixed and rotary winged aircraft. The air transport vehicle comprises a body aerodynamically designed to generate lift and a plurality of rotors that can generate lift as well as forward thrust from which a fixed wing portion of the air transport vehicle will begin to generate additional lift allowing for a sustained flight.
    Type: Application
    Filed: October 2, 2018
    Publication date: April 11, 2019
    Applicant: California Institute of Technology
    Inventors: Xichen Shi, Marcel Veismann, Christopher J. Dougherty, Stephanie Rider, Soon-Jo Chung, Morteza Gharib, Kyunam Kim, Salar Rahili, Reza Nemovi
  • Publication number: 20190046355
    Abstract: Surgical methods and related medical devices for treating ocular disorders are disclosed. Some methods relate to delivering an implant within an eye, and involve providing an elongate guide device, such as, a flexible guide member or a guide wire. A distal end of the guide device can be advanced into an anterior chamber of an eye, or through at least a portion of a site of resistance along a physiologic outflow pathway of the eye, or from an anterior chamber of the eye to a location proximate a physiologic outflow pathway of the eye. The implant is advanced along the guide device toward the guide device distal end, and is positioned to conduct aqueous humor between the anterior chamber and the physiologic outflow pathway.
    Type: Application
    Filed: June 8, 2018
    Publication date: February 14, 2019
    Inventors: Olav B. Bergheim, Morteza Gharib, Richard A. Hill
  • Publication number: 20190015604
    Abstract: A method and apparatus that enables the production of micron-scale free-standing bubbles made of liquids containing surfactants are provided. The method and apparatus of the invention overcomes the limitations of conventional bubble forming techniques by using a controlled cavitation process in a liquid media.
    Type: Application
    Filed: September 18, 2018
    Publication date: January 17, 2019
    Applicant: California Institute of Technology
    Inventors: Morteza Gharib, Daegyoum Kim
  • Patent number: 10182223
    Abstract: Hardware and software configurations, optionally, for performing profilometry of an object are disclosed. An advantageous imaging device is described. An advantageous approach to determining imager position is also described. Each aspect described may be used independently of the other. Moreover, the teaching may find use in other fields including velocimetry, etc.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: January 15, 2019
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Morteza Gharib, Alexei Harvard, Scott Hsieh, Jian Lu
  • Publication number: 20180256922
    Abstract: Systems and methods for targeting specific cell types by selective application of ultrasonic harmonic excitation at their resonance frequency (“oncotripsy”) are presented. The systems and methods result in the permeabilization, lysis, and/or death of targeted cell types by using ultrasonic harmonic excitations that have their frequency and pulse duration specifically tuned to disrupt the nuclear membrane of the targeted cells types by inducing a destructive vibrational response therein while leaving non-targeted cell types intact. Target cells may be neoplastic.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 13, 2018
    Applicant: California Institute of Technology
    Inventors: David Reza Mittelstein, Morteza Gharib, Stefanie Heyden, Michael Ortiz, Mikhail G. Shapiro
  • Publication number: 20180239168
    Abstract: A sclera or contact lens with an image of an eye that is fenestrated, or uniformly speckled with many sub-millimeter sized transparent regions or holes, is disclosed. The micro fenestrated contact lens can be worn on a strabismic, or misaligned, eye so that its image is aligned with the wearer's dominant eye. The fenestrations allow the wearer to see through the opaque or translucent image printed on the contact lens, thus allowing binocular vision even though his or her strabismic eye is covered.
    Type: Application
    Filed: February 16, 2018
    Publication date: August 23, 2018
    Inventors: Daniel M. Schwartz, Scott E. Fraser, Morteza Gharib, Sean A. Mendoza, Kevin A. Mendoza, Nicholas T. Rinella
  • Publication number: 20180229808
    Abstract: Systems, methods and apparatuses are provided for the reduction of hydrodynamic frictional drag. These systems, methods and apparatuses can include a vessel surface having an external layer and a plurality of dimples, wherein the external layer comprises a hydrophilic material, and wherein each of the dimples includes an inner surface having a superhydrophobic coating. The dimples can be configured to maintain an air-water interface as one or more fluids flow over the vessel surface. In some embodiments, a pressure reservoir can be coupled with the dimples, and can include an acoustic speaker to vibrate the air-water interface.
    Type: Application
    Filed: July 28, 2017
    Publication date: August 16, 2018
    Inventors: Cong Wang, David Jeon, Morgane Grivel, Francisco Pereira, Morteza Gharib
  • Patent number: 10039625
    Abstract: Apparatus and methods for endodontic treatment of teeth provide effective cleaning of organic material (such as pulp and diseased tissue) from the root canal system. In an embodiment, a compressor system generates high pressure liquid (e.g., water) that flows through an orifice to produce a high-velocity collimated jet of liquid. The high-velocity jet is directed toward a surface of a tooth, for example, an exposed dentinal surface, and impingement of the jet onto the surface generates an acoustic wave that propagates throughout the tooth. The acoustic wave effectively detaches organic material from dentinal surfaces and tubules. The detached organic material is flushed from the root canal system by the liquid jet and/or by additional irrigation.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: August 7, 2018
    Assignee: SONENDO, Inc.
    Inventors: Morteza Gharib, Joshua Adams, Erik Hars, Bjarne Bergheim, Karl Stocks, Lance Doherty
  • Publication number: 20180206747
    Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.
    Type: Application
    Filed: November 29, 2017
    Publication date: July 26, 2018
    Inventors: Derek Rinderknecht, Niema Pahlevan, Peyman Tavallali, Morteza Gharib
  • Patent number: 10016263
    Abstract: Apparatus and methods for endodontic treatment of teeth provide effective cleaning of organic material (such as pulp and diseased tissue) from the root canal system. In an embodiment, a compressor system generates high pressure liquid (e.g., water) that flows through an orifice to produce a high-velocity collimated jet of liquid. The high-velocity jet is directed toward a surface of a tooth, for example, an exposed dentinal surface, and impingement of the jet onto the surface generates an acoustic wave that propagates throughout the tooth. The acoustic wave effectively detaches organic material from dentinal surfaces and tubules. The detached organic material is flushed from the root canal system by the liquid jet and/or by additional irrigation.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: July 10, 2018
    Assignee: SONENDO, INC.
    Inventors: Morteza Gharib, Joshua Adams, Erik Hars, Bjarne Bergheim, Karl Stocks, Lance Doherty
  • Patent number: 10010388
    Abstract: Apparatus and methods for endodontic treatment of teeth provide effective cleaning of organic material (such as pulp and diseased tissue) from the root canal system. In an embodiment, a compressor system generates high pressure liquid (e.g., water) that flows through an orifice to produce a high-velocity collimated jet of liquid. The high-velocity jet is directed toward a surface of a tooth, for example, an exposed dentinal surface, and impingement of the jet onto the surface generates an acoustic wave that propagates throughout the tooth. The acoustic wave effectively detaches organic material from dentinal surfaces and tubules. The detached organic material is flushed from the root canal system by the liquid jet and/or by additional irrigation.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: July 3, 2018
    Assignee: SONENDO, INC.
    Inventors: Morteza Gharib, Joshua Adams, Erik Hars, Bjarne Bergheim, Karl Stocks, Lance Doherty
  • Publication number: 20180161205
    Abstract: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye. The implant is implanted into eye tissue adjacent the anterior chamber such that a proximal end of the implant resides in the anterior chamber following implantation. A therapeutic agent is eluted from the implant into the eye. Desirably, the release of the therapeutic agent from the implant is controlled. The controlled release of the therapeutic agent can be at a chosen rate and/or for a selected duration which can be episodic or periodic. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension.
    Type: Application
    Filed: October 16, 2017
    Publication date: June 14, 2018
    Inventors: Hosheng Tu, Barbara A. Niksch, David S. Haffner, Gregory T. Smedley, Olav B. Bergheim, Morteza Gharib, Richard A. Hill, Thomas W. Burns
  • Patent number: 9993368
    Abstract: Surgical methods and related medical devices for treating ocular disorders are disclosed. Some methods relate to delivering an implant within an eye, and involve providing an elongate guide device, such as, a flexible guide member or a guide wire. A distal end of the guide device can be advanced into an anterior chamber of an eye, or through at least a portion of a site of resistance along a physiologic outflow pathway of the eye, or from an anterior chamber of the eye to a location proximate a physiologic outflow pathway of the eye. The implant is advanced along the guide device toward the guide device distal end, and is positioned to conduct aqueous humor between the anterior chamber and the physiologic outflow pathway.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: June 12, 2018
    Assignee: Glaukos Corporation
    Inventors: Olav B. Bergheim, Morteza Gharib, Richard A. Hill
  • Publication number: 20180116761
    Abstract: Examples of apparatus, methods, and compositions for endodontic treatments are described. The apparatus can include a fluid platform configured to substantially retain fluid in a tooth chamber during treatment. The fluid platform can help maintain fluid circulation in the tooth chamber as fluid flows into and out of the tooth chamber. The apparatus can also include a pressure wave generator configured to generate acoustic waves that can be used for cleaning root canals and tooth surfaces in the tooth chamber. Examples of pressure wave generators include a liquid jet, an electromagnetic energy delivery device, and an ultrasonic device. The fluid can include antiseptic or antibacterial solutions to assist in tooth cleaning. The fluid may be degassed to have a reduced dissolved gas content (compared to non-degassed fluids used in endodontic treatments), which may improve the effectiveness of the pressure wave generation or the cleaning.
    Type: Application
    Filed: June 9, 2017
    Publication date: May 3, 2018
    Inventors: Bjarne Bergheim, Mehrzad Khakpour, Michele Pham, Morteza Gharib, Richard S. Tebbs
  • Publication number: 20180020955
    Abstract: Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination.
    Type: Application
    Filed: May 31, 2017
    Publication date: January 25, 2018
    Inventors: Niema Pahlevan, Peyman Tavallali, Derek Rinderknecht, Morteza Gharib
  • Patent number: 9789001
    Abstract: Implants and methods for treating ocular disorders are provided. One method involves introducing an implant into an anterior chamber of an eye. The implant is implanted into eye tissue adjacent the anterior chamber such that a proximal end of the implant resides in the anterior chamber following implantation. A therapeutic agent is eluted from the implant into the eye. Desirably, the release of the therapeutic agent from the implant is controlled. The controlled release of the therapeutic agent can be at a chosen rate and/or for a selected duration which can be episodic or periodic. The therapeutic agent can be an antiproliferative agent, an anti-inflammatory drug, or a compound for treating glaucoma or ocular hypertension.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: October 17, 2017
    Assignee: DOSE MEDICAL CORPORATION
    Inventors: Hosheng Tu, Barbara A. Niksch, David S. Haffner, Gregory T. Smedley, Olav B. Bergheim, Morteza Gharib, Richard A. Hill, Thomas W. Burns
  • Publication number: 20170273829
    Abstract: Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
    Type: Application
    Filed: February 6, 2017
    Publication date: September 28, 2017
    Inventors: Hosheng Tu, David Steven Haffner, Gregory T. Smedley, Barbara A. Niksch, Morteza Gharib, Thomas W. Burns, Richard Lindstrom
  • Publication number: 20170273758
    Abstract: Systems and methods for using a liquid jet apparatus for dental treatments are disclosed. In one implementation, the liquid jet apparatus may include a handpiece configured to deliver a high velocity liquid jet to a desired location in the mouth of a patient. The handpiece may include a positioning member having a channel through or along which the jet can propagate. The positioning member may have a distal end portion configured to be at least partially disposed in a pulp cavity, canal space, or opening in the tooth under treatment. During operation, the jet may impact an impingement surface of the distal end portion of the positioning member and be deflected as a spray through one or more openings in the distal end portion. The liquid jet apparatus may be used for root canal treatments.
    Type: Application
    Filed: November 9, 2016
    Publication date: September 28, 2017
    Inventors: Bjarne Bergheim, Morteza Gharib, Mehrzad Khakpour, Michele Pham, Richard S. Tebbs
  • Publication number: 20170258343
    Abstract: Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. The intrinsic frequencies provide metrics/ measures that correlate to the cardiac health of the subject. The systems may be used for monitoring a condition and/or is diagnosis. Exemplary uses include identifying (diagnosing) the presence of arrhythmia, heat failure, atrial fibrillation, aneurysms, vessel stenosis or aortic valve dysfunction and the necessity for valve replacement and/or monitoring congestive heart failure progression, together with identifying the acute need for hospitalization in connection with daily testing for any such condition.
    Type: Application
    Filed: May 18, 2017
    Publication date: September 14, 2017
    Inventors: Niema Pahlevan, Peyman Tavallali, Thomas Yizhao Hou, Morteza Gharib
  • Patent number: 9744037
    Abstract: Improved catheter devices for delivery, repositioning and/or percutaneous retrieval of percutaneously implanted heart valves are described, including a medical device handle that provides an array of features helpful in conducting a percutaneous heart valve implantation procedure while variously enabling radial expansion or contraction and/or lateral positioning control over the heart valve during the medical procedure.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: August 29, 2017
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Arash Kheradvar, Gregory S. Kelley, Morteza Gharib