Patents by Inventor Morteza Gharib

Morteza Gharib has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11000369
    Abstract: Improved prosthetic heart valves, their methods of manufacture, and systems and devices for manufacturing the valves are described. The prosthetic heart valves can be configured for transcatheter implantation. The prosthetic heart valves can have artificial leaflets. The prosthetic heart valves can be manufactured in numerous ways, such as by polymeric dipping processes.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: May 11, 2021
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLGY, FOLDAX, INC.
    Inventors: Morteza Gharib, Manuel Bedrossian, Stephanie Rider, Jason G. Beith
  • Publication number: 20210077234
    Abstract: Apparatus and methods for endodontic treatment of teeth provide effective cleaning of organic material (such as pulp and diseased tissue) from the root canal system. In an embodiment, a compressor system generates high pressure liquid (e.g., water) that flows through an orifice to produce a high-velocity collimated jet of liquid. The high-velocity jet is directed toward a surface of a tooth, for example, an exposed dentinal surface, and impingement of the jet onto the surface generates an acoustic wave that propagates throughout the tooth. The acoustic wave effectively detaches organic material from dentinal surfaces and tubules. The detached organic material is flushed from the root canal system by the liquid jet and/or by additional irrigation.
    Type: Application
    Filed: November 18, 2020
    Publication date: March 18, 2021
    Inventors: Morteza Gharib, Joshua Adams, Erik Hars, Bjarne Bergheim, Karl Stocks, Lance Doherty
  • Patent number: 10946148
    Abstract: A method and apparatus that enables the production of micron-scale free-standing bubbles made of liquids containing surfactants are provided. The method and apparatus of the invention overcomes the limitations of conventional bubble forming techniques by using a controlled cavitation process in a liquid media.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: March 16, 2021
    Assignee: California Institute of Technology
    Inventors: Morteza Gharib, Daegyoum Kim
  • Publication number: 20210068921
    Abstract: Examples of apparatus, methods, and compositions for endodontic treatments are described. The apparatus can include a fluid platform configured to substantially retain fluid in a tooth chamber during treatment. The fluid platform can help maintain fluid circulation in the tooth chamber as fluid flows into and out of the tooth chamber. The apparatus can also include a pressure wave generator configured to generate acoustic waves that can be used for cleaning root canals and tooth surfaces in the tooth chamber. Examples of pressure wave generators include a liquid jet, an electromagnetic energy delivery device, and an ultrasonic device. The fluid can include antiseptic or antibacterial solutions to assist in tooth cleaning. The fluid may be degassed to have a reduced dissolved gas content (compared to non-degassed fluids used in endodontic treatments), which may improve the effectiveness of the pressure wave generation or the cleaning.
    Type: Application
    Filed: September 18, 2020
    Publication date: March 11, 2021
    Inventors: Bjarne Bergheim, Mehrzad Khakpour, Michele Pham, Morteza Gharib, Richard S. Tebbs
  • Patent number: 10918291
    Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: February 16, 2021
    Assignee: California Institute of Technology
    Inventors: Derek Rinderknecht, Niema Pahlevan, Peyman Tavallali, Morteza Gharib
  • Publication number: 20210038379
    Abstract: Improved prosthetic valves, their methods of manufacture, and systems and devices for manufacturing the valves are described. The prosthetic valves can be configured for transcatheter implantation. The prosthetic valves can have artificial leaflets. The prosthetic valves can be manufactured in numerous ways, such as by polymeric dipping processes and/or electrospinning. Sponge-like polymers for valves and other medical devices are also disclosed.
    Type: Application
    Filed: March 16, 2020
    Publication date: February 11, 2021
    Inventors: Garrett Johnson, Jason G. Beith, Marek Lhotak, Praveen De Silva, Peter Millson, Francis P. Maguire, Morteza Gharib
  • Publication number: 20200359912
    Abstract: A non-invasive and convenient method and apparatus for approximation of left ventricular end diastolic pressure (LVEDP) can be used in both hospital/clinic environments and nursing home or home environments. The method and apparatus use non-invasive sensors and a new “cardiac triangle” computational method to obtain an approximation of LVEDP. The computational method uses hemodynamic and electrocardiogram (ECG) waveforms as input, which can be collected by a portable device or devices.
    Type: Application
    Filed: June 9, 2020
    Publication date: November 19, 2020
    Inventors: Morteza Gharib, Niema M. Pahlevan
  • Patent number: 10835355
    Abstract: Apparatus and methods for endodontic treatment of teeth provide effective cleaning of organic material (such as pulp and diseased tissue) from the root canal system. In an embodiment, a compressor system generates high pressure liquid (e.g., water) that flows through an orifice to produce a high-velocity collimated jet of liquid. The high-velocity jet is directed toward a surface of a tooth, for example, an exposed dentinal surface, and impingement of the jet onto the surface generates an acoustic wave that propagates throughout the tooth. The acoustic wave effectively detaches organic material from dentinal surfaces and tubules. The detached organic material is flushed from the root canal system by the liquid jet and/or by additional irrigation.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: November 17, 2020
    Assignee: SONENDO, INC.
    Inventors: Morteza Gharib, Joshua Adams, Erik Hars, Bjarne Bergheim, Karl Stocks, Lance Doherty
  • Patent number: 10806543
    Abstract: Examples of apparatus, methods, and compositions for endodontic treatments are described. The apparatus can include a fluid platform configured to substantially retain fluid in a tooth chamber during treatment. The fluid platform can help maintain fluid circulation in the tooth chamber as fluid flows into and out of the tooth chamber. The apparatus can also include a pressure wave generator configured to generate acoustic waves that can be used for cleaning root canals and tooth surfaces in the tooth chamber. Examples of pressure wave generators include a liquid jet, an electromagnetic energy delivery device, and an ultrasonic device. The fluid can include antiseptic or antibacterial solutions to assist in tooth cleaning. The fluid may be degassed to have a reduced dissolved gas content (compared to non-degassed fluids used in endodontic treatments), which may improve the effectiveness of the pressure wave generation or the cleaning.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: October 20, 2020
    Assignee: SONENDO, INC.
    Inventors: Bjarne Bergheim, Mehrzad Khakpour, Michele Pham, Morteza Gharib, Richard S. Tebbs
  • Publication number: 20200328404
    Abstract: Provided herein are electrochemical systems and related methods of making and using electrochemical systems. Electrochemical systems of the invention implement novel cell geometries and composite carbon nanomaterials based design strategies useful for achieving enhanced electrical power source performance, particularly high specific energies, useful discharge rate capabilities and good cycle life. Electrochemical systems of the invention are versatile and include secondary lithium ion cells, useful for a range of important applications including use in portable electronic devices.
    Type: Application
    Filed: June 29, 2020
    Publication date: October 15, 2020
    Inventors: Adrianus I. Aria, Morteza Gharib
  • Publication number: 20200323427
    Abstract: Systems, methods and apparatuses are provided for the measurement of intraocular pressure. These systems, methods and apparatuses can include an imaging apparatus for capturing two- or three-dimensional images or video of a patient's eye. An image reconstruction based on the captured images or video can be performed, and measurements can be taken of blood vessel features, curvature metrics, or distances between point pairs. In some embodiments, blood pressure measurements can also be taken synchronously with the captured images or video. From these measurements, a relationship between certain medical condition (e.g., elevated intraocular pressure, heart arrhythmia) and the extracted metrics can be established.
    Type: Application
    Filed: April 10, 2020
    Publication date: October 15, 2020
    Inventors: Morteza Gharib, Alexei Harvard, Alessio Tamborini, David Jeon
  • Publication number: 20200315851
    Abstract: Disclosed are example embodiments of methods and systems for inducing drug to thoroughly mix in a patient's vitreous humor. One of the systems includes: a heat transfer pad that transfer heat to or from the eyeball; and a control module electronically coupled to the heat transfer pad for controlling one or more heat transfer elements disposed thereon.
    Type: Application
    Filed: April 3, 2020
    Publication date: October 8, 2020
    Inventors: Morteza Gharib, Jinglin Huang
  • Patent number: 10787231
    Abstract: Systems, methods and apparatuses are provided for the reduction of hydrodynamic frictional drag. These systems, methods and apparatuses can include a vessel surface having an external layer and a plurality of dimples, wherein the external layer comprises a hydrophilic material, and wherein each of the dimples includes an inner surface having a superhydrophobic coating. The dimples can be configured to maintain an air-water interface as one or more fluids flow over the vessel surface. In some embodiments, a pressure reservoir can be coupled with the dimples, and can include an acoustic speaker to vibrate the air-water interface.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: September 29, 2020
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Cong Wang, David Jeon, Morgane Grivel, Francisco Pereira, Morteza Gharib
  • Publication number: 20200275077
    Abstract: Hardware and software configurations, optionally, for performing profilometry of an object are disclosed. An advantageous imaging device is described. An advantageous approach to determining imager position is also described. Each aspect described may be used independently of the other. Moreover, the teaching may find use in other fields including velocimetry, etc.
    Type: Application
    Filed: December 4, 2018
    Publication date: August 27, 2020
    Inventors: Morteza Gharib, Alexei Harvard, Scott Hsieh, Jian Lu
  • Patent number: 10742957
    Abstract: Hardware and software configurations, optionally, for performing profilometry of an object are disclosed. An advantageous imaging device is described. An advantageous approach to determining imager position is also described. Each aspect described may be used independently of the other. Moreover, the teaching may find use in other fields including velocimetry, etc.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: August 11, 2020
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Morteza Gharib, Alexei Harvard, Scott Hsieh, Jian Lu
  • Patent number: 10734639
    Abstract: Provided herein are electrochemical systems and related methods of making and using electrochemical systems. Electrochemical systems of the invention implement novel cell geometries and composite carbon nanomaterials based design strategies useful for achieving enhanced electrical power source performance, particularly high specific energies, useful discharge rate capabilities and good cycle life. Electrochemical systems of the invention are versatile and include secondary lithium ion cells, such as silicon-sulfur lithium ion batteries, useful for a range of important applications including use in portable electronic devices.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: August 4, 2020
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Adrianus I. Aria, Morteza Gharib
  • Patent number: 10702355
    Abstract: Examples of apparatus, methods, and compositions for endodontic treatments are described. The apparatus can include a fluid platform configured to substantially retain fluid in a tooth chamber during treatment. The fluid platform can help maintain fluid circulation in the tooth chamber as fluid flows into and out of the tooth chamber. The apparatus can also include a pressure wave generator configured to generate acoustic waves that can be used for cleaning root canals and tooth surfaces in the tooth chamber. Examples of pressure wave generators include a liquid jet, an electromagnetic energy delivery device, and an ultrasonic device. The fluid can include antiseptic or antibacterial solutions to assist in tooth cleaning. The fluid may be degassed to have a reduced dissolved gas content (compared to non-degassed fluids used in endodontic treatments), which may improve the effectiveness of the pressure wave generation or the cleaning.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: July 7, 2020
    Assignee: SONENDO, INC.
    Inventors: Bjarne Bergheim, Mehrzad Khakpour, Michele Pham, Morteza Gharib, Richard S. Tebbs
  • Publication number: 20200146774
    Abstract: Systems and methods for using a liquid jet apparatus for dental treatments are disclosed. In one implementation, the liquid jet apparatus may include a handpiece configured to deliver a high velocity liquid jet to a desired location in the mouth of a patient. The handpiece may include a positioning member having a channel through or along which the jet can propagate. The positioning member may have a distal end portion configured to be at least partially disposed in a pulp cavity, canal space, or opening in the tooth under treatment. During operation, the jet may impact an impingement surface of the distal end portion of the positioning member and be deflected as a spray through one or more openings in the distal end portion. The liquid jet apparatus may be used for root canal treatments.
    Type: Application
    Filed: September 19, 2019
    Publication date: May 14, 2020
    Inventors: Bjarne Bergheim, Morteza Gharib, Mehrzad Khakpour, Michele Pham, Richard S. Tebbs
  • Patent number: 10617498
    Abstract: Apparatus and methods for endodontic treatment of teeth provide effective cleaning of organic material (such as pulp and diseased tissue) from the root canal system. In an embodiment, a compressor system generates high pressure liquid (e.g., water) that flows through an orifice to produce a high-velocity collimated jet of liquid. The high-velocity jet is directed toward a surface of a tooth, for example, an exposed dentinal surface, and impingement of the jet onto the surface generates an acoustic wave that propagates throughout the tooth. The acoustic wave effectively detaches organic material from dentinal surfaces and tubules. The detached organic material is flushed from the root canal system by the liquid jet and/or by additional irrigation.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: April 14, 2020
    Assignee: SONENDO, INC.
    Inventors: Morteza Gharib, Joshua Adams, Erik Hars, Bjarne Bergheim, Karl Stocks, Lance Doherty
  • Publication number: 20200069402
    Abstract: Apparatus and methods for endodontic treatment of teeth provide effective cleaning of organic material (such as pulp and diseased tissue) from the root canal system. In an embodiment, a compressor system generates high pressure liquid (e.g., water) that flows through an orifice to produce a high-velocity collimated jet of liquid. The high-velocity jet is directed toward a surface of a tooth, for example, an exposed dentinal surface, and impingement of the jet onto the surface generates an acoustic wave that propagates throughout the tooth. The acoustic wave effectively detaches organic material from dentinal surfaces and tubules. The detached organic material is flushed from the root canal system by the liquid jet and/or by additional irrigation.
    Type: Application
    Filed: August 20, 2019
    Publication date: March 5, 2020
    Inventors: Morteza Gharib, Joshua Adams, Erik Hars, Bjarne Bergheim, Karl Stocks, Lance Doherty