Patents by Inventor Mortimer Mamelak

Mortimer Mamelak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers
    Patent number: 8778301
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: July 15, 2014
    Assignee: Orphan Medical, Inc.
    Inventors: Mortimer Mamelak, William C. Houghton, Dayton T. Reardan, Brian L. Miller
  • GAMMA-HYDROXYBUTYRATE COMPOSITIONS CONTAINING CARBOHYDRATE, LIPID OR AMINO ACID CARRIERS
    Publication number: 20130324759
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Application
    Filed: May 20, 2013
    Publication date: December 5, 2013
    Applicant: Orphan Medical, Inc.
    Inventors: Mortimer Mamelak, William C. Houghton, Dayton T. Reardan, Brian L. Miller
  • GAMMA-HYDROXYBUTYRATE COMPOSITIONS CONTAINING CARBOHYDRATE, LIPID OR AMINO ACID CARRIERS
    Publication number: 20100022643
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Application
    Filed: May 13, 2009
    Publication date: January 28, 2010
    Applicant: Orphan Medical, Inc.
    Inventors: Mortimer Mamelak, William Houghton, Dayton Reardan, Brian Miller
  • GAMMA-HYDROXYBUTYRATE COMPOSITIONS CONTAINING CARBOHYDRATE, LIPID OR AMINO ACID CARRIERS
    Publication number: 20090215890
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Application
    Filed: May 13, 2009
    Publication date: August 27, 2009
    Inventors: Mortimer Mamelak, William C. Houghton, Dayton T. Reardan, Brian L. Miller
  • Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers
    Patent number: 7572605
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: August 11, 2009
    Assignee: Orphan Medical, Inc.
    Inventors: Mortimer Mamelak, William C. Houghton, Dayton T. Reardan, Brian L. Miller
  • GHB compositions
    Publication number: 20060069040
    Abstract: The invention provides a combination of sodium gamma-hydroxybutyrate (GHB) or a prodrug or an analog thereof, with a compound that inhibits the metabolism of the GHB or GHB analog in vivo, thus prolonging or enhancing the bioactivity thereof.
    Type: Application
    Filed: September 7, 2005
    Publication date: March 30, 2006
    Inventor: Mortimer Mamelak
  • Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers
    Patent number: 7015200
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: March 21, 2006
    Assignee: Orphan Medical, Inc.
    Inventors: Mortimer Mamelak, William C. Houghton, Dayton T. Reardan, Brian L. Miller
  • Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers
    Publication number: 20050250848
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Application
    Filed: July 18, 2005
    Publication date: November 10, 2005
    Inventors: Mortimer Mamelak, William Houghton, Dayton Reardan, Brian Miller
  • Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers
    Publication number: 20040092455
    Abstract: The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.
    Type: Application
    Filed: November 3, 2003
    Publication date: May 13, 2004
    Inventors: Mortimer Mamelak, William C. Houghton, Dayton T. Reardan, Brian L. Miller
  • Pharmaceutical composition and treatment
    Patent number: 4738985
    Abstract: Sleep disorders in mammals, such as insomnia and narcolepsy, are treated by administering an effective amount of ethyl 4-acetoxybutanoate, or a closely related homolog thereof. The compounds may also be administered to mammals to cause muscle relaxation and as animal anaesthetics. Moreover the compounds appear to inhibit the release of dopamine in the brain, and are hence useful also in treatment of conditions which are associated with abnormalities of dopamine release and dopamine sensitivities, such as Parkinson's disease, schizophrenia and tardive dyskenesia.
    Type: Grant
    Filed: March 19, 1986
    Date of Patent: April 19, 1988
    Assignee: The University of Toronto Innovations Foundations
    Inventors: Ronald Kluger, Mortimer Mamelak
  • Treatment of sleep disorders
    Patent number: 4599355
    Abstract: Sleep disorders in mammals, such as insomnia and narcolepsy, are treated by administering an effective amount of ethyl 4-acetoxybutanoate, or a closely related homolog thereof.
    Type: Grant
    Filed: August 6, 1984
    Date of Patent: July 8, 1986
    Assignee: University of Toronto - Innovations Foundation
    Inventors: Ronald Kluger, Mortimer Mamelak