Abstract: Methods and compositions are disclosed for chemically bonding an antimicrobial compound to an hydroxyl bearing substrate such as cellulose, starches or leather. Cyanuric chloride (2, 4, 6 tri-chloro 1, 3, 5 triazine) is bonded to the substrate through the substrate hydroxyl and to the antimicrobial through an amine, guanido or quaternary ammonium group. The composition is: ##STR1## R.sub.1 or R.sub.2 may be chlorine or the same or different amine, guanido or quaternary ammonium containing antimicrobial. The bonding process is carried out in an aqueous solution having a pH of about 9 - 10.

Abstract: Silanized antimicrobial compounds are disclosed which are the reaction products of chlorinated phenols, bis-phenols, dihydric phenols, hydroxy diphenyl ethers and ortho or para hydroxybenzoic acids and their lower alkyl esters with an amino substituted silane having the general formulaNH.sub.2 (CH.sub.2).sub.3 Si(R).sub.3wherein R is methoxy, ethoxy or propoxy and n is 2, 3, or 4.The silane moiety is joined to the antimicrobial compound through the oxygen of a hydroxyl group of the starting compound.