Abstract: A method for the in situ treatment of diseases and malignancies in a living host body. The method includes exposing a diseased or malignant gland of a host body to an effective amount of a therapeutic agent by infusing the therapeutic agent into blood flowing from the diseased or malignant gland that has been captured and contained in an isolated section associated with the gland. The contaminated blood from this isolated section is then evacuated from the host body, cleaned, detoxified and returned to the host body without exposing other glands, organs or tissue of the host body to the contaminated blood and without interrupting the normal flow of blood circulating through the host body.

Abstract: A method is disclosed for the in situ treatment of diseases and malignancies in a living host body. The method includes exposing a diseased or malignant gland of a host body to an effective amount of a therapeutic agent by infusing the therapeutic agent into blood flowing from the diseased or malignant gland that has been captured and contained in an isolated section associated with the gland The contaminated blood from this isolated section is then evacuated from the host body, cleaned, detoxified and returned to the host body without exposing other glands, organs or tissue of the host body to the contaminated blood and without interrupting the normal flow of blood circulating through the host body. The isolated section is provided with means to prevent contaminated blood from circulating to the heart of the host body.

Abstract: An in situ treatment of an organ, such as a kidney, of a living body, having a disease or tumor. The method includes: subjecting a diseased or tumorous organ, such as a kidney, to an effective amount of a therapeutic agent, by infusing the agent via blood entering the organ, creating an isolated section in a major vein spanning the area where the tributary veins connect with the major vein, the major vein and tributary veins being directly associated with the organ; passing contaminated effluent blood from the tributary veins of the organ to the isolated section and capturing the effluent blood therein; and, evacuating the captured blood from the isolated section without exposing the contaminated effluent blood to other organs or tissues of the body and without interrupting the general circulation in the system of the body.

Abstract: An improved balloon catheter with an inferior vena cava blood shunt or bypass is provided. Posterior and anterior ports in the wall of the catheter connect to a common lumen within the catheter, forming a shunt or bypass for blood flowing in the blood vessel. The blood shunt or bypass spans the blockage in the blood vessel generated by enlargement of the balloons of the balloon catheter. Bypass port closure apparatus is provided which is operated at the external end of the catheter. The bypass port closure device functions to open and close at least one of the ports of the bypass, effectively opening and closing the bypass.