Abstract: A display device according to an example embodiment of the present disclosure may include a stretchable lower substrate; a lower pattern layer disposed on the lower substrate and including a plurality of lower plate patterns and a plurality of lower line patterns; a plurality of pixel circuits disposed on each of the plurality of lower plate patterns; a plurality of lower stretched lines disposed on each of the plurality of lower line patterns; an upper pattern layer disposed on the lower pattern layer and including a plurality of upper plate patterns and a plurality of upper line patterns; a plurality of light emitting elements disposed on each of the plurality of upper plate patterns; and a plurality of upper stretched lines disposed on each of the plurality of upper line patterns, so that a uniform power may be supplied.

Abstract: The present invention features a method of producing an immunogenic composition against a pathogen, wherein the pathogen is a virus or bacterium. Also provided is an immunogenic composition produced thereof, as well as methods of use comprising said immunogenic composition.

Abstract: Provided are drug infusion catheters comprising an axially extending elongate member, an inflatable balloon, two or more cannula each housing an extendable needle. The drug infusion catheters are useful in the delivery of drugs to tissue surrounding a lumen or vessel within a body.

Abstract: A display device according to an example embodiment of the present disclosure may include a stretchable lower substrate; a lower pattern layer disposed on the lower substrate and including a plurality of lower plate patterns and a plurality of lower line patterns; a plurality of pixel circuits disposed on each of the plurality of lower plate patterns; a plurality of lower stretched lines disposed on each of the plurality of lower line patterns; an upper pattern layer disposed on the lower pattern layer and including a plurality of upper plate patterns and a plurality of upper line patterns; a plurality of light emitting elements disposed on each of the plurality of upper plate patterns; and a plurality of upper stretched lines disposed on each of the plurality of upper line patterns, so that a uniform power may be supplied.

Abstract: System communications tailored to individual users may be dynamically provided responsive to trigger events in a virtual space. A given system communication may include one or more of a third-party advertisement, an offer for in-space products, an offer in-space services, an informative message, and/or other system communications. Trigger events may include specific user actions defined as trigger events. Current states may be obtained responsive to trigger events occurring within the virtual space. A given current state may include (1) information associated with the virtual space at a given moment, (2) information associated with a user character at a given moment, and/or (3) information associated with a user at a given moment. It may be determined whether individual current states correspond to one or more of a plurality of system communications. System communications may be provided for presentation to users via one or more communication channels.

Abstract: System communications tailored to individual users may be dynamically provided responsive to occurrences of specific activity in a virtual space. A given system communication may include one or more of a third-party advertisement, an offer for in-space products, an offer in-space services, an informative message, and/or other system communications. Specific activity may include (1) a user registers as a user in the virtual space, (2) a user establishes a relationship with another user and/or character in the virtual space, and/or (3) a user customizes a user character that is associated with the user. Current states may be obtained responsive to specific activity by a user. The system may determine whether individual current states correspond to one or more of a plurality of system communications. System communications may be provided for presentation to users via one or more communication channels.

Abstract: System communications tailored to individual users may be dynamically provided responsive to trigger events in a virtual space. A given system communication may include one or more of a third-party advertisement, an offer for in-space products, an offer in-space services, an informative message, and/or other system communications. Trigger events may include specific user actions defined as trigger events. Current states may be obtained responsive to trigger events occurring within the virtual space. A given current state may include (1) information associated with the virtual space at a given moment, (2) information associated with a user character at a given moment, and/or (3) information associated with a user at a given moment. It may be determined whether individual current states correspond to one or more of a plurality of system communications. System communications may be provided for presentation to users via one or more communication channels.

Abstract: System communications tailored to individual users may be dynamically provided responsive to trigger events in a virtual space. System communications may be sent if (1) triggered by trigger events in the virtual space, and (2) selected based on user state that is separate and discrete from the trigger events. Trigger events may include specific user actions, such as registering as a user in the virtual space. Current states may be obtained responsive to trigger events occurring. A given current state may include (1) a frequency of engagement by the first user in the virtual space, (2) an amount of real-world money spent toward the virtual space, and/or (3) total time spent by a user while engaged in gameplay in the virtual space. An individual system communication is selected and provided for presentation to a user responsive to an individual current state corresponding to the individual system communication.

Abstract: An immunogenic composition for use as a blood-stage malaria vaccine, a method of producing the immunogenic composition and a method of treatment of malaria are provided. The immunogenic composition includes isolated or purified merozoites, or red blood cells infected with merozoites, treated with centanamycin or tafuramycin A. The immunogenic composition does not include an adjuvant. A single dose of the immunogenic composition is sufficient to protect an animal against subsequent malaria infection by the same isolate, strain or species of Plasmodium used in the immunogenic composition, or by one or more heterologous isolates, strains or species of Plasmodium.

Abstract: System communications tailored to individual users may be dynamically provided responsive to trigger events in a virtual space. A given system communication may include one or more of a third-party advertisement, an offer for in-space products, an offer in-space services, an informative message, and/or other system communications. Trigger events may include specific user actions defined as trigger events. Current states may be obtained responsive to trigger events occurring within the virtual space. A given current state may include (1) information associated with the virtual space at a given moment, (2) information associated with a user character at a given moment, and/or (3) information associated with a user at a given moment. It may be determined whether individual current states correspond to one or more of a plurality of system communications. System communications may be provided for presentation to users via one or more communication channels.

Abstract: An immunogenic composition for use as a blood-stage malaria vaccine, a method of producing the immunogenic composition and a method of treatment of malaria are provided. The immunogenic composition includes isolated or purified merozoites, or red blood cells infected with merozoites, treated with centanamycin or tafuramycin A. The immunogenic composition does not include an adjuvant. A single dose of the immunogenic composition is sufficient to protect an animal against subsequent malaria infection by the same isolate, strain or species of Plasmodium used in the immunogenic composition, or by one or more heterologous isolates, strains or species of Plasmodium.

Abstract: The present invention provides the maximum convenient portability with a 3 foldable method of the water ski hull, one half dividable shaft method of ski pole and a separable propulsion plate method from the ski pole, a push-pull method of rudder, and a separable method of the lateral balancing board from the hull, and also provides the maximum lateral balance effect of a skier by means of the lateral balancing board at the mid section, two side wings at the stern section, and a foot skid pad on each side of the mid section and a Velcro belt on each side holding each side instep of a skier over each side foot skid pad of the mid section of the ski hull.

Abstract: Colorants are disclosed that exhibit high color strength, bright shades, and high thermal stability. Such compounds have found application as colorants for polyethylene terephthalate (“PET”). Potential end uses include disperse dyes, non-warping pigments, decolorizable colorants, and the like. Compounds and methods for synthesis include benzodifuranone related compounds, benzene centered lactones, benzene centered lactams; benzene-centered thiolactones; naphthalene-centered lactones; naphthalene-centered lactams; naphthalene-centered thiolactones; anthraquinone-centered lactones; anthraquinone-centered lactams; anthraquinone-centered thiolactones; anthracene-centered lactones; anthracene-centered lactams; anthracene-centered thiolactones; hetero-aromatic-centered lactones; hetero-aromatic centered lactams and hetero-aromatic centered thiolactone compounds, and the like. Furthermore, resins such as PET or other polymeric resins containing the compounds are disclosed.

Abstract: The present invention relates to novel achiral seco-analogues of DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II, III, IV and V: wherein X is a good leaving group, such as a chloride, a bromide, an iodide, a mesylate, a tosylate, an acetate, a quaternary ammonium moiety, a mercaptan, an alkylsulfoxyl, or an alkylsulfonyl group, preferably either a chloride, a bromide, or an iodide group. R1 is a suitable minor groove binding agent to enhance the interactions of the achiral seco-cyclopropaneindole (Cl) or an achiral seco-duocarmycin with specific sequences of DNA.

Abstract: The present invention relates to novel achiral seco-analogues of the DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II III, IV and V: 1

Abstract: A Toilet Tissue Holder that comes in different styles, embodiments and colors such as pastels, translucent, and all primary colors, and/or combinations of colors. The frame is made of plastice; this unique toilet tissue holder comes manual and/or automatic which dispenses and reverses 6 to 8 sheets of toilet tissue at the push of a button, an economical way of saving toilet tissue. Also comes with the combination of light(s) with off and on light switch or button, digital clock, electronic and/or digital CD player or tape player or 2 to 5 inch T.V. or AM/FM radio or CD player and AM/FM radio, or tape player and AM/FM radio or 2 to 5 inch T.V. and AM/FM radio and speaker(s); these various features can come with any of the following electronic control switches, buttons, or knobs such as power, play, pause, stop, elect, rewind, reverse, forward, tuning, tracking, search, repeat, bass, treble, program, seconds, and skip, etc.