Abstract: In one embodiment, the present disclosure provides a combination of recombinant Ara h 1 and Ara h 2 variant polypeptides lacking at least one epitope recognized by anti-Ara h 1 antibodies and anti-Ara h 2 antibodies, respectively, thereby having reduced or abolished antibody binding to the peanut allergen. These peanut allergen variants may be used in methods of treating subjects allergic to peanuts and reducing the severity of their allergy.

Abstract: A de-epitoped high molecular weight (HMW) glutenin is provided. Methods of generating same, and uses thereof are also provided.

Abstract: A de-epitoped alpha gliadin is provided. Methods of generating same and uses thereof are also provided.

Abstract: A method for identifying an epitope of a wheat T cell immunogen is provided. The method comprises identifying an epitope on the wheat T cell immunogen for the ability to bind a major histocompatibility complex (MHC) class II, thereby identifying the epitope of a wheat T cell immunogen.

Abstract: Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.

Abstract: Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.

Abstract: Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.

Abstract: Single dye fluorescent staining, microscopic imaging, and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). By use of microscopic imaging, such as confocal imaging, this allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections, including those that eventually lead to sepsis.

Abstract: Provided are improved hip prosthetic devices that reduce the risk of hip dislocation upon performing artificial hip replacement. The improved hip prosthetic devices comprise a flexible bumper configured to extend from the acetabular component and prevent contact between the femoral neck and the acetabular component. The bumper may be an acetabular capsule inserted in collaboration with a standard hip prosthetic device, and attached to a standard acetabular liner. The capsule has a bumper region that cushions contact between the femoral neck and the acetabular component, thereby preventing impingement and dislocation, both common in patients in which known hip prosthetic devices are used. Alternatively, an improved acetabular liner comprises an integral bumper which prevents impingement of the femoral neck and acetabular components, thereby reducing dislocation risk and securing the femoral head within the acetabular liner.

Abstract: Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.

Abstract: Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration (MIC)), thereby providing a means for rapid Antibiotic Susceptibility Testing (AST). This allows for a quick and easy means for clinicians to determine a suitable treatment regimen for patients suffering from bacterial infections and those that eventually lead to sepsis.

Abstract: The present invention provides a method for detecting and/or identifying specific bacteria within an uncultured sample. The method comprises steps selected inter alia from (a) obtaining an absorption spectrum (AS) of said uncultured sample; (b) acquiring the n dimensional volume boundaries for said specific bacteria; (c) data processing said AS; and, (d) detecting and/or identifying said specific bacteria if said m1 statistical correlation and/or said m features are within said n dimensional volume.

Abstract: The present invention provides an optical unit (320) adapted to accommodate a sample and to enable optical detection of infection within said sample; said optical unit comprising a body (100); said body is characterized by a distal end and a proximal end interconnected via a main longitudinal axis; said body (100) comprising at least one mirror (50) coupled to said distal end; wherein said mirror (50) having a proximal and distal surfaces; said proximal surface faces said mask; said proximal surface is adapted to accommodate said sample.

Abstract: This disclosure provides a method for detecting and/or identifying uncultured bacteria. The sample is an aerosol sample selected from a group consisting of cough, sneeze, saliva, mucus, bile, urine, vaginal secretions, middle ear aspirate, pus, pleural effusions, synovial fluid, abscesses, cavity swabs, serum, blood and spinal fluid. The method comprises obtaining absorption spectra (AS) of the sample, extracting and processing the acquired data, thereby detecting and/or identifying the bacteria.

Abstract: The present invention provides a method for detecting and/or identifying specific bacteria within an uncultured sample, comprising steps of: a. obtaining an absorption spectrum (AS) of said uncultured sample; b. acquiring the n dimensional volume boundaries for said specific bacteria; c. data processing said AS; i. noise reducing; ii. extracting m features from said entire AS; iii. dividing said AS into several segments according to said m features; iv. calculating m1 features of each of said segment; and, d. detecting and/or identifying said specific bacteria if said m1 features and/or said m features are within said n dimensional volume; wherein said bacteria is a antibiotics resistance bacteria.

Abstract: The present invention provides a method for detecting and/or identifying specific bacteria within an uncultured sample. The method comprises steps selected inter alia from (a) obtaining an absorption spectrum (AS) of said uncultured sample; (b) acquiring the n dimensional volume boundaries for said specific bacteria; (c) data processing said AS; and, (d) detecting and/or identifying said specific bacteria if said m1 statistical correlation and/or said m features are within said n dimensional volume.

Abstract: Some demonstrative embodiments of the invention include a system and a method for disinfection of a liquid including monitoring the disinfection process. The system may include a short-path light detector located in proximity to the illumination source to detect the intensity of light emitted from the illumination source at a short distance from the source. The system may include at least one additional long-path light detector located in proximity to the transparent walls of the conduit of liquid to be disinfected that detects light emitted from the illumination source after propagating in the liquid and exiting through the transparent walls.

Abstract: Some demonstrative embodiments of the invention include a system and a method for disinfection of a liquid including monitoring the disinfection process. The system may include a short-path light detector located in proximity to the illumination source to detect the intensity of light emitted from the illumination source at a short distance from the source. The system may include at least one additional long-path light detector located in proximity to the transparent walls of the conduit of liquid to be disinfected that detects light emitted from the illumination source after propagating in the liquid and exiting through the transparent walls.

Abstract: Apparatus for assaying an analyte in a patient's body comprising: at least one sensor unit mountable to a region of the patient's skin comprising at least one light source that illuminates a tissue region below the skin with light that generates photoacoustic waves therein and at least one acoustic transducer that generates signals responsive to the photoacoustic waves; and a control unit configured to be mounted to a different part of the body and comprising a controller for controlling the at least one light source and at least one acoustic transducer and receiving the signals generated by the at least one acoustic transducer.

Abstract: Dividing a multiplexed optical signal transmitted along a first transmission path into two portions and diverting one of the two portions to a second transmission path and forwarding the other portion of the multiplexed optical signal along that first transmission path, while the energy of the diverted portion comprises the entire spectrum of the multiplexed optical signal. Preferably, the diverted first portion is further divided into at least two parts, each comprising a wavelength range substantially different than the others, and at least one of the two parts is forwarded towards an optical receiver.