Patents by Inventor Moshe Ligumski

Moshe Ligumski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of lipid conjugates in the treatment of disease
    Patent number: 8501701
    Abstract: The invention relates to methods of use for compounds in treating, reducing the incidence, reducing the severity or pathogenesis of an intestinal disease or condition in a subject, including, inter alia, inflammatory bowel disease, Crohn's disease, ulcerative colitis, or a combination thereof.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: August 6, 2013
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Use of lipid conjugates in the treatment of disease
    Publication number: 20070117779
    Abstract: The invention relates to methods of use for compounds in treating, reducing the incidence, reducing the severity or pathogenesis of an intestinal disease or condition in a subject, including, inter alia, inflammatory bowel disease, Crohn's disease, ulcerative colitis, or a combination thereof.
    Type: Application
    Filed: November 14, 2006
    Publication date: May 24, 2007
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Use of lipid conjugates in the treatment of diseases
    Patent number: 7141552
    Abstract: The invention provides a method for treating a subject suffering from an intestinal disease, including, inter alia, Crohn's disease, ulcerative colitis, immuno-inflammatory intestinal injury, drug-induced enteropathy and ischemia-induced intestinal injury. This invention further provides a pharmaceutical composition for treating a subject suffering from an intestinal disease, including, inter alia, a lipid or phospholipid moiety bonded to a physiologically acceptable monomer, dimer, oligomer, or polymer, and a pharmaceutically acceptable carrier or excipient.
    Type: Grant
    Filed: March 2, 2004
    Date of Patent: November 28, 2006
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Use of lipid conjugates in the treatment of disease
    Patent number: 7034006
    Abstract: The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE conjugates) manifest an unexpectedly wide range of pharmacological effects, including stabilizing cell membranes; limiting oxidative damage to cell and blood components; limiting cell proliferation, cell extravasation and (tumor) cell migratory behavior; suppressing immune responses; and attenuating physiological reactions to stress, as expressed in elevated chemokine levels.
    Type: Grant
    Filed: January 10, 2001
    Date of Patent: April 25, 2006
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Saul Yedgar, David Shuseyov, Gershon Golomb, Reuven Reich, Isaac Ginsburg, Abd-al-Roof Higazi, Moshe Ligumski, Miron Krimsky, David Ojcius, Benito Antonio Yard, Fokko Johannes van der Woude, Edit Schnitzer
  • Use of lipid conjugates in the treatment of diseases
    Publication number: 20040229842
    Abstract: The invention provides a method for treating a subject suffering from an intestinal disease, including, inter alia, Crohn's disease, ulcerative colitis, immuno-inflammatory intestinal injury, drug-induced enteropathy and ischemia-induced intestinal injury. This invention further provides a pharmaceutical composition for treating a subject suffering from an intestinal disease, including, inter alia, a lipid or phospholipid moiety bonded to a physiologically acceptable monomer, dimer, oligomer, or polymer, and a pharmaceutically acceptable carrier or excipient.
    Type: Application
    Filed: March 2, 2004
    Publication date: November 18, 2004
    Inventors: Saul Yedgar, Moshe Ligumski, Miron Krimsky
  • Use of lipid conjugates in the treatment of disease
    Publication number: 20020049183
    Abstract: The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomers and polymers (PE conjugates) manifest an unexpectedly wide range of pharmacological effects, including stabilizing cell membranes; limiting oxidative damage to cell and blood components; limiting cell proliferation, cell extravasation and (tumor) cell migratory behavior; suppressing immune responses; and attenuating physiological reactions to stress, as expressed in elevated chemokine levels.
    Type: Application
    Filed: January 10, 2001
    Publication date: April 25, 2002
    Inventors: Saul Yedgar, David Shuseyov, Gershon Golomb, Reuven Reich, Isaac Ginsburg, Abd-al-Roof Higazi, Moshe Ligumski, Miron Krimsky, David Ojcius, Benito Antonio Yard, Fokko Johannes van der Woude, Edit Schnitzer