Abstract: There is provided in accordance with an exemplary embodiment of the invention a method of osteointegration of an implant into surrounding jaw-bone, the method comprising: applying a magnetic field around an implant, the magnetic field produced around the implant to a jaw-bone depth of up to at least about 7 mm, the magnetic field having a magnetic flux density of about 0.05-0.5 mT at up to at least about 2 mm from a surface of the implant, the magnetic field produced by a coil within the implant. A device adapted for insertion into a jawbone implant and for producing the magnetic field for bone enhancement of surrounding jawbone is also described.

Abstract: There is provided in accordance with an exemplary embodiment of the invention a method of osteointegration of an implant into surrounding jaw-bone, the method comprising: applying a magnetic field around an implant, the magnetic field produced around the implant to a jaw-bone depth of up to at least about 7 mm, the magnetic field having a magnetic flux density of about 0.05-0.5 mT at up to at least about 2 mm from a surface of the implant, the magnetic field produced by a coil within the implant. A device adapted for insertion into a jawbone implant and for producing the magnetic field for bone enhancement of surrounding jawbone is also described.

Abstract: There is provided in accordance with an exemplary embodiment of the invention a method of osteointegration of an implant into surrounding jaw-bone, the method comprising: applying a magnetic field around an implant, the magnetic field produced around the implant to a jaw-bone depth of up to at least about 7 mm, the magnetic field having a magnetic flux density of about 0.05-0.5 mT at up to at least about 2 mm from a surface of the implant, the magnetic field produced by a coil within the implant. A device adapted for insertion into a jawbone implant and for producing the magnetic field for bone enhancement of surrounding jawbone is also described.

Abstract: An implant device for stimulating osteogenesis and osseointegration comprises a hollow annular housing member, a pulsed current modulator, and a coil connected to the current modulator. The current modulator and at least a portion of the coil are mounted within the housing member. A frequency of the pulsed current is selected to generate an electromagnetic field of a predetermined flux density that penetrates, and propagates radially outwardly from, the housing member for a sufficiently large propagation distance to stimulate osteogenesis and osseointegration, by means of the generated electromagnetic field, of a bone region in which the implant device is implanted and which is disposed radially outwardly from the housing member.

Abstract: There is provided in accordance with an exemplary embodiment of the invention a method of osteointegration of an implant into surrounding jaw-bone, the method comprising: applying a magnetic field around an implant, the magnetic field produced around the implant to a jaw-bone depth of up to at least about 7 mm, the magnetic field having a magnetic flux density of about 0.05-0.5 mT at up to at least about 2 mm from a surface of the implant, the magnetic field produced by a coil within the implant. A device adapted for insertion into a jawbone implant and for producing the magnetic field for bone enhancement of surrounding jawbone is also described.

Abstract: The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

Abstract: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

Abstract: An implant device for stimulating osteogenesis and osseointegration comprises a hollow annular housing member, a pulsed current modulator, and a coil connected to the current modulator. The current modulator and at least a portion of the coil are mounted within the housing member. A frequency of the pulsed current is selected to generate an electromagnetic field of a predetermined flux density that penetrates, and propagates radially outwardly from, the housing member for a sufficiently large propagation distance to stimulate osteogenesis and osseointegration, by means of the generated electromagnetic field, of a bone region in which the implant device is implanted and which is disposed radially outwardly from the housing member.

Abstract: The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a block-co-polymers comprising a non-biodegradable polymer and a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.

Abstract: The present invention provides compositions for extended release of an active ingredient, comprising a lipid-saturated matrix formed from a biodegradable polymer. The present invention also provides methods of producing the matrix compositions and methods for using the matrix compositions to provide controlled release of an active ingredient in the body of a subject in need thereof.