Patents by Inventor Moshe Weitzberg

Moshe Weitzberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
    Patent number: 8748627
    Abstract: The present invention relates to compounds of formula (I), which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: June 10, 2014
    Assignee: AbbVie Inc.
    Inventors: Yu Gui Gu, Moshe Weitzberg, Xiangdong Xu, Richard F. Clark, Tianyuan Zhang, Qun Li, Todd M. Hansen, Hing Sham, Bruce A. Beutel, Heidi S. Camp, Xiaojun Wang
  • Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
    Patent number: 8735595
    Abstract: The present invention relates to compounds of formula (I) which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: May 27, 2014
    Assignee: AbbVie Inc.
    Inventors: Yu Gui Gu, Xiangdong Xu, Moshe Weitzberg, Hing L. Sham
  • Antibacterial compounds
    Patent number: 8163769
    Abstract: Antibacterials having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophylaxis and treatment of bacterial infections using the compounds are disclosed.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: April 24, 2012
    Assignee: Abbott Laboratories
    Inventors: David Anderson, Bruce Beutel, Todd D. Bosse, Richard Clark, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Todd Matthew Hansen, Mira Hinman, Douglas Kalvin, Daniel P. Larson, Linda Lynch, Zhenkun Ma, Christopher Motter, Fabio Palazzo, Teresa Rosenberg, Tamara Rehm, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong, Tianyuan Zhang
  • Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
    Patent number: 7928243
    Abstract: The present invention relates to compounds of formula (I): Pharmaceutical compositions and methods that are useful in the treatment or prevention of metabolic diseases or conditions are also provided.
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: April 19, 2011
    Assignee: Abbott Laboratories
    Inventors: Yu Gui Gu, Richard F. Clark, Qun Li, Moshe Weitzberg, Hing Sham
  • NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME
    Publication number: 20080161368
    Abstract: The present invention relates to compounds of formula (I): Pharmaceutical compositions and methods that are useful in the treatment or prevention of metabolic diseases or conditions are also provided.
    Type: Application
    Filed: December 5, 2007
    Publication date: July 3, 2008
    Inventors: Yu Gui Gu, Richard F. Clark, Qun Li, Moshe Weitzberg, Hing Sham
  • NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME
    Publication number: 20070225332
    Abstract: The present invention relates to compounds of formula (I), which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Application
    Filed: February 15, 2007
    Publication date: September 27, 2007
    Inventors: Yu Gui Gu, Moshe Weitzberg, Xiangdong Xu, Richard Clark, Tianyuan Zhang, Qun Li, Todd Hansen, Hing Sham, Bruce Beutel, Heidi Camp, Xiaojun Wang
  • NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME
    Publication number: 20070219251
    Abstract: The present invention relates to compounds of formula (I) which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Application
    Filed: February 15, 2007
    Publication date: September 20, 2007
    Inventors: Yu Gui Gu, Xiangdong Xu, Moshe Weitzberg, Hing Sham
  • Novel acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
    Publication number: 20060178400
    Abstract: The present invention relates to compounds of formula (I), which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
    Type: Application
    Filed: November 7, 2005
    Publication date: August 10, 2006
    Inventors: Bruce Beutel, Heidi Camp, Richard Clark, Yu-Gui Gu, Todd Hansen, Robert Keyes, Qun Li, Gang Liu, Hing Sham, Xiaojun Wang, Moshe Weitzberg, Zhili Xin, Xiangdong Xu, Tianyuan Zhang
  • Antibacterial compounds
    Patent number: 6818654
    Abstract: Antibacterials having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophylaxis and treatment of bacterial infections using the compounds are disclosed.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: November 16, 2004
    Assignee: Abbott Laboratories
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Linda Lynch, Zhenkun Ma, Christopher Motter, Teresa Rosenberg, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong
  • Antibacterial compounds
    Publication number: 20040072817
    Abstract: Antibacterials having formula (I) 1
    Type: Application
    Filed: March 12, 2003
    Publication date: April 15, 2004
    Inventors: David Anderson, Bruce Beutel, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Mira Hinman, Douglas Kalvin, Linda Lynch, Zhenkun Ma, Christopher Motter, Teresa Rosenberg, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong
  • Antibacterial compounds
    Publication number: 20030232818
    Abstract: Antibacterials having formula (I) 1
    Type: Application
    Filed: March 12, 2003
    Publication date: December 18, 2003
    Inventors: David Anderson, Bruce Beutel, Todd D. Bosse, Richard Clark, Curt Cooper, Peter Dandliker, Caroline David, Yu-Gui Gu, Todd Matthew Hansen, Mira Hinman, Douglas Kalvin, Daniel P. Larson, Linda Lynch, Zhenkun Ma, Christopher Motter, Fabio Palazzo, Teresa Rosenberg, Tamara Rehm, William Sanders, Michael Tufano, Rolf Wagner, Moshe Weitzberg, Hong Yong, Tianyuan Zhang
  • Naphthamidine urokinase inhibitors
    Patent number: 6495562
    Abstract: Compounds having the formula are inhibitors of urokinase and are useful in the treatment of diseases in which urokinase plays a role. Also disclosed are urokinase-inhibiting compositions, methods for the preparation of urokinase-inhibitors, and a method of inhibiting urokinase in a mammal.
    Type: Grant
    Filed: April 25, 2001
    Date of Patent: December 17, 2002
    Assignee: Abbott Laboratories
    Inventors: Milan Bruncko, Christopher Robin Dalton, Vincent Louis Giranda, Jianchun Gong, Willian J. McClellan, Vicki L. Nienaber, Todd Warren Rockway, Daryl Richard Sauer, Moshe Weitzberg
  • Urokinase inhibitors
    Publication number: 20010049374
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: May 8, 2001
    Publication date: December 6, 2001
    Inventors: Andrew W. Steele, William J. McClellan, Todd W. Rockway, Kent D. Stewart, Moshe Weitzberg, Michael D. Wendt, Vicki L. Nienaber
  • Ukokinase inhibitors
    Patent number: 6284796
    Abstract: Compounds having the formula are inhibitors of urokinase and are useful in the treatment of diseases in which urokinase plays a role. Also disclosed are urokinase-inhibiting compositions and a method of inhibiting urokinase in a mammal.
    Type: Grant
    Filed: January 25, 1999
    Date of Patent: September 4, 2001
    Assignee: Abbott Laboratories
    Inventors: Andrew G. Geyer, William J. McClellan, Todd W. Rockway, Kent D. Stewart, Moshe Weitzberg, Michael D. Wendt
  • Urokinase inhibitors
    Patent number: 6258822
    Abstract: Compounds having the formula are inhibitors of urokinase and are useful in the treatment of diseases in which urokinase plays a role. Also disclosed are urokinase-inhibiting compositions and a method of inhibiting urokinase in a mammal.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: July 10, 2001
    Assignee: Abbott Laboratories
    Inventors: Andrew G. Geyer, William J. McClellan, Todd W. Rockway, Kent D. Stewart, Moshe Weitzberg, Michael D. Wendt
  • Method for treating inflammation and compounds and compositions suitable for use therein
    Patent number: 5079260
    Abstract: The present invention relates to a method of treating an inflammatory condition, and to compounds and composition suitable for use in such a method, which compounds have the Formula: ##STR1## wherein: X is methylene, ethylene, ethyleneoxy, or oxygen;Q is ##STR2## where C' is a residue of a lipophilic amino acid, and Y is --CO.sub.2 H, --CH.sub.2 OH, --CONR.sub.1 R.sub.2, or --CO.sub.2 R.sub.1 where R.sub.1 and R.sub.2 hydrogen, alkyl, or aryl;R.sub.3 and R.sub.4 are, independently, hydrogen, alkyl or aryl; andA and B are, independently, hydrogen, fused phenyl, alkyl, aryl, alkaryl, aralkyl, alkoxy, alkoxyalkyl, halogen, or nitro;or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: May 29, 1990
    Date of Patent: January 7, 1992
    Assignee: Nova Pharmaceutical Corporation
    Inventors: Moshe Weitzberg, Ronald Burch, Barry Shearer
  • 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
    Patent number: 4843074
    Abstract: Novel 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts and their use as antimuscarinic agents having antisecretory activity selective for the gastrointestinal tract are disclosed. The compounds have the formula: ##STR1## wherein: X=H, halogen, lower alkyl, lower alkoxy, hydroxy, andR=morpholinyl, thiomorpholinyl, piperidinyl, 1,4-dioxa-8-azaspiro[4.5]decanyl, 4-(2,6-dimethylmorpholinyl), 4-ketopiperidinyl, 4-hydroxypiperidinyl, 4-substituted piperazinyl (wherein the substituent is lower alkyl, hydroxyalkyl, acetoxyalkyl, or acyl).Also disclosed are pharmaceutical compositions for treatment of irritable bowel syndrome and methods for using such compounds.
    Type: Grant
    Filed: May 17, 1988
    Date of Patent: June 27, 1989
    Assignee: Marion Laboratories, Inc.
    Inventors: Waclaw J. Rzeszotarski, Vicki H. Audia, Moshe Weitzberg