Patents by Inventor Motoaki Ohtsubo

Motoaki Ohtsubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoassays for human cyclin E
    Patent number: 5861259
    Abstract: Methods are provided for determining in biological material the presence or amount human cyclin E polypeptide and/or cyclin E:cell division kinase complexes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 19, 1999
    Assignee: Fred Hutchinson Cancer Research
    Inventors: James M. Roberts, Motoaki Ohtsubo, Andrew C. Koff, Frederick Cross
  • Human cyclin E
    Patent number: 5807698
    Abstract: Nucleic acid molecules capable of hybridizing under stringent conditions to the nucleotide sequence residing between positions 1 and 1185 of the human cyclin E cDNA sequence shown in FIG. 2. Polypeptides encoded by such nucleic acid molecules, and immunologic binding partners directed to such polypeptides.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 15, 1998
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: James M. Roberts, Motoaki Ohtsubo, Andrew C. Koff, Frederick Cross
  • Human cyclin E polypeptides
    Patent number: 5783661
    Abstract: Nucleic acid molecules capable of hybridizing under stringent conditions to the nucleotide sequence residing between positions 1 and 1185 of the human cyclin E cDNA sequence shown in FIG. 2. Polypeptides encoded by such nucleic acid molecules, and immunologic binding partners directed to such polypeptides.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 21, 1998
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: James M. Roberts, Motoaki Ohtsubo, Andrew C. Koff, Frederick Cross
  • Assays for compounds that modulate or alter cyclin E activity
    Patent number: 5645999
    Abstract: Whole cell or cell-free test systems for screening and identifying compounds that modulate or alter Cyclin E activity. Whole cell assays measure the G1 phase of cells in the presence or absence of the test compound. Additional whole cell or cell-free assays measure binding of cyclin E to a cell division kinase, measure cyclin E activity directly, or measure the cell division kinase activity directly in the presence or absence of the test compound.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 8, 1997
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: James M. Roberts, Motoaki Ohtsubo, Andrew C. Koff, Frederick Cross
  • Human cyclin E
    Patent number: 5449755
    Abstract: Nucleic acid molecules capable of hybridizing under stringent conditions to the nucleotide sequence residing between positions 1 and 1185 of the human cyclin E cDNA sequence shown in FIG. 2 . Polypeptides encoded by such nucleic acid molecules, and immunologic binding partners directed to such polypeptides.
    Type: Grant
    Filed: September 16, 1992
    Date of Patent: September 12, 1995
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: James M. Roberts, Motoaki Ohtsubo, Andrew C. Koff, Frederick Cross