Patents by Inventor Motoji Kokushi

Motoji Kokushi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzene derivatives and method of treating arteriosclerosis with benzene derivatives
    Patent number: 5462958
    Abstract: The present invention provides a novel benzene derivative useful as a preventive and medically treating medicine for arteriosclerosis, and a cholesterol O-acyl transferase inhibitor comprising the benzene derivative as an active ingredient.The benzene derivative according to the present invention is represented by the following general formula (I): ##STR1## wherein R.sup.1 represents a carboxyl group which may be protected or a group represented by the formula: ##STR2## wherein R.sup.5 represents a lower alkyl group or a hydroxyalkyl group and R.sup.6 represents a hydrogen atom or a hydroxyl group; R.sup.2 represents a hydrogen atom, a lower alkyl group or the like; R.sup.3 and R.sup.4 each represent a hydrogen atom or a hydroxyl group; and p is an integer of 1 to 6.
    Type: Grant
    Filed: May 19, 1994
    Date of Patent: October 31, 1995
    Assignee: Eisai Co., Ltd.
    Inventors: Kenji Hayashi, Nobuhisa Watanabe, Koichi Nose, Hiroshi Tanaka, Issei Ohtsuka, Motoji Kokushi, Hironobu Hiyoshi, Hiroko Kobayashi, Toshie Yamada, Toru Horie