Patents by Inventor Motoya Katsuki

Motoya Katsuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ES cells having enhanced RNAi effect
    Publication number: 20070033663
    Abstract: The object of the present invention is to provide ES cells and mammals having enhanced RNAi effect, which can be used to analyze gene functions at an individual level. The present invention provides ES cells having enhanced RNAi effect, which are obtained by performing genetic manipulation on ES cells.
    Type: Application
    Filed: October 5, 2006
    Publication date: February 8, 2007
    Applicant: Mitsubishi Chemical Corporation
    Inventors: Motoya Katsuki, Mitsuyoshi Ishida, Minoru Kato
  • Method for producing non-human mammal having RNAi phenotype
    Publication number: 20050283845
    Abstract: It is an object of the present invention to develop a novel method for producing mammals such as mice having an RNAi phenotype, thereby enabling the production of RNAi-expressed progenies by a new mechanism to transfer information to progenies, and to improve a method for introducing dsRNA to improve the efficiency of obtaining mammals such as mice having an RNAi phenotype. The present invention provides a method for producing a non-human mammal with suppressed function of a target gene, which comprises injecting the double-stranded RNA (dsRNA) of the garget gene into the nucleus of a cell.
    Type: Application
    Filed: June 3, 2005
    Publication date: December 22, 2005
    Applicant: Mitsubishi Chemical Corporation
    Inventors: Motoya Katsuki, Mitsuyoshi Ishida
  • Method for producing non-human mammal RNAi phenotype using papilloma virus vector
    Publication number: 20050229266
    Abstract: It is an object of the present invention to improve a method for introducing dsRNA, so as to improve the efficiency of obtaining mammals such as mice having an RNAi phenotype. The present invention provides a method for producing a non-human mammal wherein the function of a target gene is suppressed, which comprises introducing into cells a papilloma virus vector into which the target gene has been incorporated.
    Type: Application
    Filed: January 14, 2005
    Publication date: October 13, 2005
    Applicant: Mitsubishi Chemical Corporation
    Inventors: Motoya Katsuki, Mitsuyoshi Ishida, Takeharu Morishita
  • ES cells having enhanced RNAi effect
    Publication number: 20050003541
    Abstract: The object of the present invention is to provide ES cells and mammals having enhanced RNAi effect, which can be used to analyze gene functions at an individual level. The present invention provides ES cells having enhanced RNAi effect, which are obtained by performing genetic manipulation on ES cells.
    Type: Application
    Filed: May 13, 2004
    Publication date: January 6, 2005
    Applicant: Mitsubishi Chemical Corporation
    Inventors: Motoya Katsuki, Mitsuyoshi Ishida, Minoru Kato
  • Transgenic animal having drug metabolism enzyme gene and utilization thereof
    Publication number: 20040073958
    Abstract: An object of the present invention is to provide a transgenic animal which is useful in a test for forecasting fetal toxicity and teratogenicity of drugs. The present invention provides a transgenic non-human animal or a part thereof wherein several foreign (human-type) proteins which are involved in the drug metabolism or mutant proteins thereof are expressed in the body; a recombinant gene which is useful for the production of said non-human animal; and a method for screening a substance having fetal toxicity and teratogenicity using said non-human animal.
    Type: Application
    Filed: September 11, 2003
    Publication date: April 15, 2004
    Inventors: Motoya Katsuki, Tetsuya Kamataki, Yutaka Teranishi, Mitsuyoshi Ishida, Minoru Kato
  • Recombinant gene containing inverted repeat sequence and utilization thereof
    Publication number: 20040010130
    Abstract: The object of the present invention is to improve a method for introducing dsRNA in such a way that RNAi effect is sustained in mammalian (mainly mouse) cells for a long period of time. The present invention provides a recombinant gene which contains inverted repeats of a target gene which can be expressed in mammalian cells.
    Type: Application
    Filed: June 16, 2003
    Publication date: January 15, 2004
    Inventors: Motoya Katsuki, Mitsuyoshi Ishida, Minoru Kato