Patents by Inventor Motukuri Mahesh

Motukuri Mahesh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective enrichment of high-quality DNA intact sperms from a semen sample
    Patent number: 11926847
    Abstract: Disclosed is a composition for selective enrichment of progressively motile non-fragmented/intact DNA sperms during swim-up of semen sample comprising combination of electrolytes, a mix of excipients, polyyvinylpyrrolidone, recombinant human serum albumin or bovine serum albumin. A method of selective enrichment of DNA-intact sperms using the compositions of the present invention is also disclosed. The DNA fragmentation index of the swim-up sperms are less than the DNA fragmentation index of the neat samples. The media compositions of the present invention are applicable for enrichment of non-fragmented/intact DNA sperms for therapeutic purposes in the field of assisted reproductive technologies.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: March 12, 2024
    Assignee: Sanzyme Biologics Private Limited
    Inventors: Raunak Jay Soman, Jay Soman, Motukuri Mahesh
  • SELECTIVE ENRICHMENT OF HIGH-QUALITY DNA INTACT SPERMS FROM A SEMEN SAMPLE
    Publication number: 20210155898
    Abstract: Disclosed is a composition for selective enrichment of progressively motile non-fragmented/intact DNA sperms during swim-up of semen sample comprising combination of electrolytes, a mix of excipients, polyyvinylpyrrolidone, recombinant human serum albumin or bovine serum albumin. A method of selective enrichment of DNA-intact sperms using the compositions of the present invention is also disclosed. The DNA fragmentation index of the swim-up sperms are less than the DNA fragmentation index of the neat samples. The media compositions of the present invention are applicable for enrichment of non-fragmented/intact DNA sperms for therapeutic purposes in the field of assisted reproductive technologies.
    Type: Application
    Filed: April 3, 2019
    Publication date: May 27, 2021
    Applicant: Sanzyme Biologics Private Limited
    Inventors: Raunak Jay Soman, Jay Soman, Motukuri Mahesh