Patents by Inventor Mou-Tuan Huang

Mou-Tuan Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10570161
    Abstract: A new family of therapeutics which provides a controlled-release delivery platform for non-steroidal anti-inflammatory agents on an ester or an ester-carbonate backbone is disclosed herein. These agents are reversible inhibitors of acetylcholinesterase and are thus useful for clinical conditions benefiting from inflammation suppression and cholinergic intervention. These compounds are of the general formula wherein n=0, 1; X=C, Si, and N+ and NSAID=ibuprofen, naproxen, indomethacin and diclofenac. Other embodiments are also disclosed.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: February 25, 2020
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, LEHIGH UNIVERSITY
    Inventors: Jeffrey D. Laskin, Diane E. Heck, Mou-Tuan Huang, Karine Fabio, Carl J. Lacey, Sherri C. Young, Pramod Mohanta, Christophe Guillon, Ned D. Heindel
  • Publication number: 20170143836
    Abstract: A new family of therapeutics which provides a controlled-release delivery platform for non-steroidal anti-inflammatory agents on an ester or an ester-carbonate backbone is disclosed herein. These agents are reversible inhibitors of acetylcholinesterase and are thus useful for clinical conditions benefiting from inflammation suppression and cholinergic intervention. These compounds are of the general formula wherein n=0, 1; X?C, Si, and N+ and NSAID=ibuprofen, naproxen, indomethacin and diclofenac. Other embodiments are also disclosed.
    Type: Application
    Filed: November 30, 2016
    Publication date: May 25, 2017
    Inventors: Jeffrey D. Laskin, Diane E. Heck, Mou-Tuan Huang, Karine Fabio, Jeffrey C. Lacey, Sherri C. Young, Pramod Mohanta, Christophe Gullion, Ned D. Heindel
  • Patent number: 8431550
    Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors in skin cells that have not yet been damaged by ultraviolet radiation.
    Type: Grant
    Filed: October 20, 2003
    Date of Patent: April 30, 2013
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Miri Seiberg, Mou-Tuan Huang, Connie Beozhen Lin, Stanley S. Shapiro, Christine Kirkland, Allan H. Conney
  • Patent number: 8343971
    Abstract: This application relates to pharmacologically-active vanilloid compounds which are useful for the treatment of various anti-inflammatory states characterized by inhibition of FAAH, such as, Alzheimer's dementia, Parkinson's disease, depression, pain, rheumatoid arthritis, pathophysiology of mood disorders, multiple sclerosis, and inflammation, or antagonism of TRPV1, such as, for example, Huntington's disease, hypertension, arthritis, allergic airway inflammation, Crohn's disease, ulcerative colitis, and neuropathic pain.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: January 1, 2013
    Assignees: Rutgers, The State University of New Jersey, The University of Medicine and Dentistry of New Jersey, Lehigh University
    Inventors: Jeffrey D. Laskin, Diane E. Heck, Carl Jeffrey Lacey, Erik Aponte, Mou-Tuan Huang, Ned D. Heindel
  • Publication number: 20120059007
    Abstract: This application relates to pharmacologically-active vanilloid compounds which are useful for the treatment of various anti-inflammatory states characterized by inhibition of FAAH, such as, Alzheimer's dementia, Parkinson's disease, depression, pain, rheumatoid arthritis, pathophysiology of mood disorders, multiple sclerosis, and inflammation, or antagonism of TRPV1, such as, for example, Huntington's disease, hypertension, arthritis, allergic airway inflammation, Crohn's disease, ulcerative colitis, and neuropathic pain.
    Type: Application
    Filed: September 15, 2010
    Publication date: March 8, 2012
    Inventors: Jeffrey D. Laskin, Diane E. Heck, Carl Jeffrey Lacey, Erik Aponte, Mou-Tuan Huang, Ned D. Heindel
  • Publication number: 20110195138
    Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.
    Type: Application
    Filed: November 18, 2008
    Publication date: August 11, 2011
    Inventors: Nicholi Vorsa, Irina O. Vvedenskaya, Mou-Tuan Huang, Robert T. Rosen, Sharon L. Rosen
  • Patent number: 7879823
    Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: February 1, 2011
    Assignee: Johnson & Johnson Consumer Companies
    Inventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang
  • Publication number: 20070292539
    Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.
    Type: Application
    Filed: August 20, 2007
    Publication date: December 20, 2007
    Inventors: Nicholi Vorsa, Irina Vvedenskaya, Mou-Tuan Huang, Robert Rosen, Sharon Rosen
  • Patent number: 7309688
    Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: December 18, 2007
    Assignees: Johnson & Johnson Consumer Companies, Rutgers, The State University of New Jersey
    Inventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang
  • Patent number: 7288680
    Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: October 30, 2007
    Assignees: Wellgen, Inc., Rutgers, The State University of New Jersey
    Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert T. Rosen, Slavik Dushenkov
  • Patent number: 7270837
    Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: September 18, 2007
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Nicholi Vorsa, Irina O. Vvedenskaya, Mou-Tuan Huang, Sharon L. Rosen, legal representative, Robert T Rosen, deceased
  • Patent number: 7201928
    Abstract: Compositions and methods of inhibiting tumor cell growth and treating and preventing cancer are provided based on administration of an orange peel extract either alone or in combination with other phytochemicals.
    Type: Grant
    Filed: September 20, 2000
    Date of Patent: April 10, 2007
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Mou Tuan Huang, Chi-Tang Ho, Robert T. Rosen, Geetha Ghai, Martin Lipkin, Kuang Yu Chen, Nitin Telang, Charles Boyd, Katalin Csiszar
  • Publication number: 20060241154
    Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
    Type: Application
    Filed: June 23, 2006
    Publication date: October 26, 2006
    Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert Rosen, Slavik Dushenkov
  • Patent number: 7087790
    Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: August 8, 2006
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert T. Rosen, Slavik Dushenkov
  • Publication number: 20060088610
    Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.
    Type: Application
    Filed: November 10, 2004
    Publication date: April 27, 2006
    Inventors: Nicholi Vorsa, Irina Vvedenskaya, Mou-Tuan Huang, Robert Rosen, Sharon Rosen
  • Publication number: 20050244523
    Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.
    Type: Application
    Filed: April 7, 2005
    Publication date: November 3, 2005
    Inventors: Miri Seiberg, Stanley Shapiro, Christine Paine, Allan Conney, Mou-Tuan Huang
  • Publication number: 20050049284
    Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.
    Type: Application
    Filed: August 29, 2003
    Publication date: March 3, 2005
    Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert Rosen, Slavik Dushenkov
  • Publication number: 20040247713
    Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.
    Type: Application
    Filed: July 6, 2004
    Publication date: December 9, 2004
    Inventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang
  • Publication number: 20030064049
    Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.
    Type: Application
    Filed: March 27, 2002
    Publication date: April 3, 2003
    Inventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang