Patents by Inventor Mou-Tuan Huang
Mou-Tuan Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10570161Abstract: A new family of therapeutics which provides a controlled-release delivery platform for non-steroidal anti-inflammatory agents on an ester or an ester-carbonate backbone is disclosed herein. These agents are reversible inhibitors of acetylcholinesterase and are thus useful for clinical conditions benefiting from inflammation suppression and cholinergic intervention. These compounds are of the general formula wherein n=0, 1; X=C, Si, and N+ and NSAID=ibuprofen, naproxen, indomethacin and diclofenac. Other embodiments are also disclosed.Type: GrantFiled: November 30, 2016Date of Patent: February 25, 2020Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, LEHIGH UNIVERSITYInventors: Jeffrey D. Laskin, Diane E. Heck, Mou-Tuan Huang, Karine Fabio, Carl J. Lacey, Sherri C. Young, Pramod Mohanta, Christophe Guillon, Ned D. Heindel
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Publication number: 20170143836Abstract: A new family of therapeutics which provides a controlled-release delivery platform for non-steroidal anti-inflammatory agents on an ester or an ester-carbonate backbone is disclosed herein. These agents are reversible inhibitors of acetylcholinesterase and are thus useful for clinical conditions benefiting from inflammation suppression and cholinergic intervention. These compounds are of the general formula wherein n=0, 1; X?C, Si, and N+ and NSAID=ibuprofen, naproxen, indomethacin and diclofenac. Other embodiments are also disclosed.Type: ApplicationFiled: November 30, 2016Publication date: May 25, 2017Inventors: Jeffrey D. Laskin, Diane E. Heck, Mou-Tuan Huang, Karine Fabio, Jeffrey C. Lacey, Sherri C. Young, Pramod Mohanta, Christophe Gullion, Ned D. Heindel
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Patent number: 8431550Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors in skin cells that have not yet been damaged by ultraviolet radiation.Type: GrantFiled: October 20, 2003Date of Patent: April 30, 2013Assignee: Johnson & Johnson Consumer Companies, Inc.Inventors: Miri Seiberg, Mou-Tuan Huang, Connie Beozhen Lin, Stanley S. Shapiro, Christine Kirkland, Allan H. Conney
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Patent number: 8343971Abstract: This application relates to pharmacologically-active vanilloid compounds which are useful for the treatment of various anti-inflammatory states characterized by inhibition of FAAH, such as, Alzheimer's dementia, Parkinson's disease, depression, pain, rheumatoid arthritis, pathophysiology of mood disorders, multiple sclerosis, and inflammation, or antagonism of TRPV1, such as, for example, Huntington's disease, hypertension, arthritis, allergic airway inflammation, Crohn's disease, ulcerative colitis, and neuropathic pain.Type: GrantFiled: September 15, 2010Date of Patent: January 1, 2013Assignees: Rutgers, The State University of New Jersey, The University of Medicine and Dentistry of New Jersey, Lehigh UniversityInventors: Jeffrey D. Laskin, Diane E. Heck, Carl Jeffrey Lacey, Erik Aponte, Mou-Tuan Huang, Ned D. Heindel
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Publication number: 20120059007Abstract: This application relates to pharmacologically-active vanilloid compounds which are useful for the treatment of various anti-inflammatory states characterized by inhibition of FAAH, such as, Alzheimer's dementia, Parkinson's disease, depression, pain, rheumatoid arthritis, pathophysiology of mood disorders, multiple sclerosis, and inflammation, or antagonism of TRPV1, such as, for example, Huntington's disease, hypertension, arthritis, allergic airway inflammation, Crohn's disease, ulcerative colitis, and neuropathic pain.Type: ApplicationFiled: September 15, 2010Publication date: March 8, 2012Inventors: Jeffrey D. Laskin, Diane E. Heck, Carl Jeffrey Lacey, Erik Aponte, Mou-Tuan Huang, Ned D. Heindel
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Publication number: 20110195138Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.Type: ApplicationFiled: November 18, 2008Publication date: August 11, 2011Inventors: Nicholi Vorsa, Irina O. Vvedenskaya, Mou-Tuan Huang, Robert T. Rosen, Sharon L. Rosen
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Patent number: 7879823Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.Type: GrantFiled: July 6, 2004Date of Patent: February 1, 2011Assignee: Johnson & Johnson Consumer CompaniesInventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang
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Publication number: 20070292539Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.Type: ApplicationFiled: August 20, 2007Publication date: December 20, 2007Inventors: Nicholi Vorsa, Irina Vvedenskaya, Mou-Tuan Huang, Robert Rosen, Sharon Rosen
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Patent number: 7309688Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.Type: GrantFiled: March 27, 2002Date of Patent: December 18, 2007Assignees: Johnson & Johnson Consumer Companies, Rutgers, The State University of New JerseyInventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang
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Patent number: 7288680Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.Type: GrantFiled: June 23, 2006Date of Patent: October 30, 2007Assignees: Wellgen, Inc., Rutgers, The State University of New JerseyInventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert T. Rosen, Slavik Dushenkov
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Patent number: 7270837Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.Type: GrantFiled: November 10, 2004Date of Patent: September 18, 2007Assignee: Rutgers, The State University of New JerseyInventors: Nicholi Vorsa, Irina O. Vvedenskaya, Mou-Tuan Huang, Sharon L. Rosen, legal representative, Robert T Rosen, deceased
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Patent number: 7201928Abstract: Compositions and methods of inhibiting tumor cell growth and treating and preventing cancer are provided based on administration of an orange peel extract either alone or in combination with other phytochemicals.Type: GrantFiled: September 20, 2000Date of Patent: April 10, 2007Assignee: Rutgers, The State University of New JerseyInventors: Mou Tuan Huang, Chi-Tang Ho, Robert T. Rosen, Geetha Ghai, Martin Lipkin, Kuang Yu Chen, Nitin Telang, Charles Boyd, Katalin Csiszar
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Publication number: 20060241154Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.Type: ApplicationFiled: June 23, 2006Publication date: October 26, 2006Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert Rosen, Slavik Dushenkov
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Patent number: 7087790Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.Type: GrantFiled: August 29, 2003Date of Patent: August 8, 2006Assignee: Rutgers, The State University of New JerseyInventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert T. Rosen, Slavik Dushenkov
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Publication number: 20060088610Abstract: The present invention is directed to extracts of cranberries (Vaccinium macrocarpon) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-?-xylopyranoside, quercetin-3-?-glucoside, quercetin-3-?-arabinopyranoside, 3?-methoxyquercetin-3-?-xylopyranoside, quercetin-3-O-(6?-p-coumaroyl)-?-galactoside, and quercetin-3-O-(6?-benzoyl)-?-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-?-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.Type: ApplicationFiled: November 10, 2004Publication date: April 27, 2006Inventors: Nicholi Vorsa, Irina Vvedenskaya, Mou-Tuan Huang, Robert Rosen, Sharon Rosen
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Publication number: 20050244523Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.Type: ApplicationFiled: April 7, 2005Publication date: November 3, 2005Inventors: Miri Seiberg, Stanley Shapiro, Christine Paine, Allan Conney, Mou-Tuan Huang
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Publication number: 20050049284Abstract: The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.Type: ApplicationFiled: August 29, 2003Publication date: March 3, 2005Inventors: Chi-Tang Ho, Geetha Ghai, Shengmin Sang, Jin-Woo Jhoo, Mou-Tuan Huang, Robert Rosen, Slavik Dushenkov
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Publication number: 20040247713Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.Type: ApplicationFiled: July 6, 2004Publication date: December 9, 2004Inventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang
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Publication number: 20030064049Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.Type: ApplicationFiled: March 27, 2002Publication date: April 3, 2003Inventors: Miri Seiberg, Stanley S. Shapiro, Christine Paine, Allan H. Conney, Mou-Tuan Huang