Patents by Inventor Mourad Hamedi

Mourad Hamedi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of [(1R), 2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2, 1-F][1,2,4]triazin-6-yloxy]-1-methylethyl ester
    Patent number: 7671199
    Abstract: The invention relates to an improved process for preparing [(1R), 2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester of the formula: Compound I has been shown to be useful for the treatment of certain types of cancer.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: March 2, 2010
    Assignee: Britsol-Myers Squibb Company
    Inventors: Gerard A. Crispino, Mourad Hamedi, Thomas L. LaPorte, John E. Thornton, Jaan A. Pesti, Zhongmin Xu, Paul C. Lobben, David K. Leahy, Jale Muslehiddinoglu, Chiajen Lai, Lori Ann Spangler, Robert P. Discordia, Francis S. Gibson
  • PROCESS FOR THE PREPARATION OF [(1R), 2S]-2-AMINOPROPIONIC ACID 2-[4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLO[2,1-f][1,2,4]TRIAZIN-6-YLOXY]-1-METHYLETHYL ESTER
    Publication number: 20070249610
    Abstract: The invention relates to an improved process for preparing [(1R),2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester of the formula: Compound I has been shown to be useful for the treatment of certain types of cancer.
    Type: Application
    Filed: April 20, 2007
    Publication date: October 25, 2007
    Inventors: Gerard Crispino, Mourad Hamedi, Thomas LaPorte, John Thornton, Jaan Pesti, Zhongmin Xu, Paul Lobben, David Leahy, Jale Muslehiddinoglu, Chiajen Lai, Lori Spangler, Robert Discordia
  • Continuous process for producing hydroxyazapirones by oxidation
    Publication number: 20050165233
    Abstract: A method for continuous production of hydroxyazapirones, for example 6-hydroxybuspirone, using a modified reactor. The products of the invention are useful as pharmaceutical agents.
    Type: Application
    Filed: November 15, 2004
    Publication date: July 28, 2005
    Inventors: Mourad Hamedi, Thomas LaPorte, Daniel Watson, Lifen Shen, Eric Dowdy, Jeffrey Depue, Yeung Chan
  • Method and apparatus for optimizing throughput in a trickle bed reactor
    Publication number: 20050135978
    Abstract: The geometry of the reactor is tailored to increase the heat transfer capacity of the initial sections of the reactor columns where the greatest heat is generated. This is accomplished by reducing the inner diameter of the initial column sections relative to that of the final column sections and by increasing the rate of heat transfer from to the coolant proximate the initial column sections by increasing the velocity of coolant surrounding the initial column sections. Further, the coolant flow is directed in a direction perpendicular to the axis of each column by spaced, laterally offset baffles.
    Type: Application
    Filed: October 8, 2004
    Publication date: June 23, 2005
    Inventors: Mourad Hamedi, Thomas LaPorte, Yeung Chan