Patents by Inventor Moushumi Paul

Moushumi Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics
    Patent number: 7785825
    Abstract: Lantibiotics are synthesized on ribosomes as prepeptides and post-translationally modified to a mature form. These modifications include dehydrations and cyclizations. Compounds and related methods of generating compounds, modified by dehydration, cyclization, or dehydration and cyclization, are disclosed. The disclosure includes in vitro approaches to effecting dehydration and cyclization leading to production of biologically active compounds such as lantibiotics and variants thereof. Synthetic variants and methods including combinatorial approaches for generating diverse lantibiotics and other compounds are disclosed. The invention has broad potential for applications including food, agricultural, and medical industries.
    Type: Grant
    Filed: January 12, 2005
    Date of Patent: August 31, 2010
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Willem A. van der Donk, Lili Xie, Champak Chatterjee, Moushumi Paul
  • Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics
    Publication number: 20050164339
    Abstract: Lantibiotics are synthesized on ribosomes as prepeptides and post-translationally modified to a mature form. These modifications include dehydrations and cyclizations. Compounds and related methods of generating compounds, modified by dehydration, cyclization, or dehydration and cyclization, are disclosed. The disclosure includes in vitro approaches to effecting dehydration and cyclization leading to production of biologically active compounds such as lantibiotics and variants thereof. Synthetic variants and methods including combinatorial approaches for generating diverse lantibiotics and other compounds are disclosed. The invention has broad potential for applications including food, agricultural, and medical industries.
    Type: Application
    Filed: January 12, 2005
    Publication date: July 28, 2005
    Inventors: Willem van der Donk, Lili Xie, Champak Chatterjee, Moushumi Paul