Patents by Inventor Moussa Alkhalaf

Moussa Alkhalaf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic animals overexpressing MDM2
    Patent number: 6028245
    Abstract: The present invention relates to transgenic, non-human animals overexpressing a MDM2 gene. These animals model MDM2 over-expression associated with human tumors, display a major phenotype characterized by the severe skin disorder ichthyosis, and are useful for identifying compounds for the treatment of human disease. Therefore, the invention also relates to methods of using the animals for identifying compounds effective for the treatment of diseases of the skin and respiratory tract, and to the compounds themselves.
    Type: Grant
    Filed: June 25, 1998
    Date of Patent: February 22, 2000
    Assignees: Rhone-Poulenc Rorer SA, Institut National de la Sante et de la Recherche Medicale
    Inventors: Bohdan Wasylyk, Bruno Tocque, Moussa Alkhalaf