Patents by Inventor Mridula Kadalbajoo

Mridula Kadalbajoo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pteridinones for the treatment of cancer
    Patent number: 9351974
    Abstract: Compounds of Formula I, as shown below and defined herein: pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven or mediated at least in part by RSK. This Abstract is not limiting of the invention.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: May 31, 2016
    Assignee: OSI Pharmaceuticals, LLC
    Inventors: Meizhong Jin, Mridula Kadalbajoo, An-Hu Li, Mark J. Mulvihill, Kam W. Siu, Arno G. Steinig, Jing Wang
  • DIHYDROPTERIDINONES
    Publication number: 20140315911
    Abstract: Compounds of Formula I, as shown below and defined herein: pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven or mediated at least in part by RSK. This Abstract is not limiting of the invention.
    Type: Application
    Filed: November 12, 2012
    Publication date: October 23, 2014
    Inventors: Meizhong Jin, Mridula Kadalbajoo, An-Hu Li, Mark J. Mulvihill, Kam W. Siu, Arno G. Steinig, Jing Wang
  • Substituted imidazopyr- and imidazotri-azines
    Patent number: 8481733
    Abstract: Fused pyridine-based bicyclic compounds having the structure of Formula I, as defined herein, pharmaceutically acceptable salts thereof, preparation, compositions, and disease treatment therewith. This abstract does not define or limit the invention.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: July 9, 2013
    Assignee: OSI Pharmaceuticals, LLC
    Inventors: Andrew P. Crew, Meizhong Jin, Mridula Kadalbajoo, Andrew Kleinberg, Mark J. Mulvihill, Jing Wang
  • Bicyclic protein kinase inhibitors
    Patent number: 7648987
    Abstract: Compounds of the Formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit protein kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: January 19, 2010
    Assignee: OSI Pharmaceuticals, Inc.
    Inventors: Andrew Philip Crew, Han-Qing Dong, Mark Joseph Mulvihill, Douglas S. Werner, Mridula Kadalbajoo, Radoslaw Laufer
  • SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES
    Publication number: 20090286768
    Abstract: Fused pyridine-based bicyclic compounds having the structure of Formula I, as defined herein, pharmaceutically acceptable salts thereof, preparation, compositions, and disease treatment therewith. This abstract does not define or limit the invention.
    Type: Application
    Filed: May 19, 2009
    Publication date: November 19, 2009
    Applicant: OSI Pharmaceuticals, Inc.
    Inventors: Andrew P. Crew, Meizhong Jin, Mridula Kadalbajoo, Andrew Kleinberg, Mark J. Mulvihill, Jing Wang
  • Biosensors
    Publication number: 20090075396
    Abstract: Methods for detecting a biological interaction comprising administering a substrate comprising a ligand attached to the substrate wherein the ligand binds to a receptor and wherein a signal is produced. Also disclosed is a biosensor comprising a substrate and a ligand wherein the ligand is attached to the surface of the substrate and wherein the ligand preferentially binds to a receptor.
    Type: Application
    Filed: September 10, 2008
    Publication date: March 19, 2009
    Applicant: University of Maryland Office of Technology Commercialization
    Inventors: Philip R. Deshong, Douglas S. English, Daniel C. Stein, Mridula Kadalbajoo, Fehmi Damkaci
  • Biosensors
    Publication number: 20070249063
    Abstract: Methods for detecting a biological interaction comprising administering a substrate comprising a ligand attached to the substrate wherein the ligand binds to a receptor and wherein a signal is produced. Also disclosed is a biosensor comprising a substrate and a ligand wherein the ligand is attached to the surface of the substrate and wherein the ligand preferentially binds to a receptor.
    Type: Application
    Filed: August 30, 2005
    Publication date: October 25, 2007
    Inventors: Philip Deshong, Douglas English, Daniel Stein, Mridula Kadalbajoo, Fehmi Damkaci
  • Bicyclic protein kinase inhibitors
    Publication number: 20070149521
    Abstract: Compounds of the Formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit protein kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.
    Type: Application
    Filed: December 4, 2006
    Publication date: June 28, 2007
    Inventors: Andrew Crew, Han-Qing Dong, Mark Mulvihill, Douglas Werner, Mridula Kadalbajoo, Radoslaw Laufer