Abstract: This disclosure relates to methods of treating plaque psoriasis comprising administering an anti-IL-23p19 antibody hum13B8-b to a patient in need thereof. This disclosure also relates to pharmaceutical compositions of an anti-IL-23p19 antibody hum13B8-b or antigen binding fragment thereof for the treatment plaque psoriasis in a patient. This disclosure further relates to the use of an anti-IL-23p19 antibody hum13B8-b or antigen binding fragment thereof for the manufacture of a medicament for treating plaque psoriasis in a patient.

Abstract: The present invention relates to a composite extract of Cocculus hirsutus for use in the prevention and treatment of dengue and its pharmaceutical compositions. Further, it provides for a stable pharmaceutical composition comprising a therapeutically effective amount of the said extract for use in the treatment of dengue virus infection in a mammal. It also provides for a method for reducing viral load in the treatment of dengue virus infection by administering the composite extract or its pharmaceutical composition to a mammal in need thereof.