Patents by Inventor Muhammad Altaf

Muhammad Altaf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GOLD COMPLEX-CONTAINING CANCER ACTIVITY COMPOSITION
    Publication number: 20190040089
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Application
    Filed: August 24, 2018
    Publication date: February 7, 2019
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB
  • Gold(I) complexes, pharmaceutical compositions thereof, and methods of treating proliferative disorders
    Patent number: 10189865
    Abstract: Gold(I) complexes as antiproliferative or antitumor agents. The gold(I) ion is connected to a N-heterocyclic carbene and further coordinated to a selone ligand. Also described are a pharmaceutical composition incorporating the gold(I) complex, a method of synthesizing the gold(I) complex, and a method for treating a proliferative disorder (e.g.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: January 29, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Adam A. A. Sulaiman, Muhammad Altaf, Anvarhusein A. Isab
  • GOLD(III) COMPLEXES AS ANTICANCER AGENTS AND A METHOD OF TREATING CANCER
    Publication number: 20190023721
    Abstract: Gold(III) complexes containing mixed ligands. A method of treating cancer with these complexes is disclosed. The complexes are cytotoxic to prostate, breast, ovarian, and Hodgkin lymphoma cancer cell lines. These complexes were either more potent than cisplatin or had similar potency to cisplatin.
    Type: Application
    Filed: July 20, 2017
    Publication date: January 24, 2019
    Applicant: King Fahd University of Petroleum and Minerals
    Inventors: Anvar Husain Abdul Kadir ISAB, Muhammad Altaf
  • Method for inhibiting cancer cell growth with a transplatin complex
    Patent number: 10172823
    Abstract: The invention is directed to platinum(II) thione complexes of formula (I) and to methods of treating cancer using these complexes.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: January 8, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mohammed Y. Jomaa, Muhammad Altaf, Anvarhusein A. Isab
  • Method for inducing cytotoxicity in cancer cells
    Patent number: 10160773
    Abstract: A method for treating a proliferative disease, disorder, or condition comprising administering a gold(III) complex such as [Au(npen)Cl2]Cl.2H2O (1) or [Au(npen)2]Cl3 (2); the complexes, and methods for making them.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: December 25, 2018
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Anvarhusein A. Isab, Muhammad Altaf
  • MONONUCLEOTIDE-DITHIOCARBAMATE COMPLEX
    Publication number: 20180362555
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Application
    Filed: August 24, 2018
    Publication date: December 20, 2018
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB
  • DNA/DITHIOCARBAMATO PHOSPHINE METAL COMPLEX
    Publication number: 20180362556
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Application
    Filed: August 24, 2018
    Publication date: December 20, 2018
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB
  • CANCER CELL-CONTAINING COMPOSITION
    Publication number: 20180362557
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Application
    Filed: August 24, 2018
    Publication date: December 20, 2018
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
  • Gold complexes of alkylated phosphines
    Patent number: 10144749
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: December 4, 2018
    Assignees: King Fahd University of Petroleum and Minerals, King Saud University
    Inventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
  • GOLD(I) COMPLEXES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF TREATING CANCER
    Publication number: 20180298042
    Abstract: Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamte ligands are connected by Au(I)-Au(l) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer.
    Type: Application
    Filed: November 9, 2017
    Publication date: October 18, 2018
    Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
    Inventors: Anvarhusein A. ISAB, Muhammad Altaf, Adam Ahmed Abdallah Seliman
  • Composition containing a gold (I) complex and cancer cells
    Patent number: 10093689
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: October 9, 2018
    Assignees: King Fahd University of Petroleum and Minerals, King Saud University
    Inventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
  • Gold(I) complexes with anticancer properties and methods of use thereof
    Patent number: 10092579
    Abstract: Monomeric and dimeric gold(I) complexes as anticancer agents. The gold(I) complexes are coordinated to mixed ligands: one phosphine-based ligand that may be monodentate or bidentate and at least one dithiocarbamate-based ligand that is monodentate. Pharmaceutical compositions incorporating the gold(I) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis are also provided.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: October 9, 2018
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Muhammad Altaf, Muhammad Monim-Ul-Mehboob, Anvarhusein Abdulkadir Isab, Saleh Altuwaijri
  • PLATINUM(II) COMPLEXES WITH SELONE LIGANDS AND METHOD OF USE
    Publication number: 20180273566
    Abstract: Platinum(II) complexes with various selones (L) having the general formula PtL2Cl2 are disclosed. The platinum(II) complexes of the invention inhibit growth of cancer cells in vitro and are useful for treatment of proliferative disorders such as cancers and/or tumors.
    Type: Application
    Filed: March 22, 2018
    Publication date: September 27, 2018
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Anvarhusein A. ISAB, Muhammad ALTAF, Ali ALHOSHANI, Ali Osman ALTOUM, Mohammed Yagoub JOMAA
  • COMPOSITION CONTAINING A GOLD (I) COMPLEX AND CANCER CELLS
    Publication number: 20180273558
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Application
    Filed: May 25, 2018
    Publication date: September 27, 2018
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB
  • GOLD COMPLEXES OF ALKYLATED PHOSPHINES
    Publication number: 20180273559
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Application
    Filed: May 30, 2018
    Publication date: September 27, 2018
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
  • Mixed ligand gold(I) complexes as anti-cancer agents
    Patent number: 10077280
    Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: September 18, 2018
    Assignees: King Fahd University of Petroleum and Minerals, King Saud University
    Inventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
  • METHOD FOR INDUCING CYTOTOXICITY IN CANCER CELLS
    Publication number: 20180251477
    Abstract: A method for treating a proliferative disease, disorder, or condition comprising administering a gold(III) complex such as [Au(npen)Cl2]Cl.2H2O (1) or [Au(npen)2]Cl3 (2); the complexes, and methods for making them.
    Type: Application
    Filed: May 7, 2018
    Publication date: September 6, 2018
    Applicant: King Fahd University of Petroleum and Minerals
    Inventors: Anvarhusein A. Isab, Muhammad Altaf
  • Anticancer activity of gold(III) complexes of meso-1,2-di(1-naphthyl)-1,2-diaminoethane
    Patent number: 9994592
    Abstract: A method for treating a proliferative disease, disorder, or condition comprising administering a gold(III) complex such as [Au(npen)Cl2]Cl.2H2O (1) or [Au(npen)2]Cl3 (2); the complexes, and methods for making them.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: June 12, 2018
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Anvarhusein A. Isab, Muhammad Altaf
  • Transplatin derivatives as anticancer agents
    Patent number: 9974765
    Abstract: The invention is directed to platinum(II) thione complexes of formula (I) and to methods of treating cancer using these complexes.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: May 22, 2018
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mohammed Y. Jomaa, Muhammad Altaf, Anvarhusein A. Isab
  • ANTICANCER ACTIVITY OF GOLD(III) COMPLEXES OF MESO-1,2-DI(1-NAPHTHYL)-1,2-DIAMINOETHANE
    Publication number: 20180111951
    Abstract: A method for treating a proliferative disease, disorder, or condition comprising administering a gold(III) complex such as [Au(npen)Cl2]Cl.2H2O (1) or [Au(npen)2]Cl3 (2); the complexes, and methods for making them.
    Type: Application
    Filed: October 19, 2017
    Publication date: April 26, 2018
    Applicant: King Fahd University of Petroleum and Minerals
    Inventors: Anvarhusein A. ISAB, Muhammad ALTAF