Abstract: Methods for seismic imaging of a subterranean geological formation include receiving first acoustic impedance data, having a first resolution, associated with wells in a subsurface region. A system receives seismic data including second acoustic impedance data having a second resolution. The system performs a quality control process configured to identify a mismatch between the first acoustic impedance data and the second acoustic impedance data. The system resamples the second acoustic impedance data into a three-dimensional (3D) grid model. The system scales up the first acoustic impedance data into the 3D grid model. The system downscales the second acoustic impedance data controlled by the first acoustic impedance data in the 3D grid model. The system generates third acoustic impedance data representing fine-scale impedance data. The system extrapolates the fine-scale impedance into areas or regions having no seismic data coverage or poor seismic data coverage.

Abstract: This disclosure provides a chemically modified induced pluripotent stem (iPS) cell derived from parental cells and methods for generating the chemically induced pluripotent stem (iPS) cells, as well as cardiac progenitor cells capable of producing cells of multiple sub-lineages. The iPS cells are useful in method for or regenerating cardiac muscle tissue or to promote the replacement of cardiac scar tissue or to rejuvenating cardiac muscles in a patient in need thereof and to treat cardiac disease.

Abstract: Methods for seismic imaging of a subterranean geological formation include receiving first acoustic impedance data, having a first resolution, associated with wells in a subsurface region. A system receives seismic data including second acoustic impedance data having a second resolution. The system performs a quality control process configured to identify a mismatch between the first acoustic impedance data and the second acoustic impedance data. The system resamples the second acoustic impedance data into a three-dimensional (3D) grid model. The system scales up the first acoustic impedance data into the 3D grid model. The system downscales the second acoustic impedance data controlled by the first acoustic impedance data in the 3D grid model. The system generates third acoustic impedance data representing fine-scale impedance data. The system extrapolates the fine-scale impedance into areas or regions having no seismic data coverage or poor seismic data coverage.

Abstract: A 3D facies model generator system and methods thereof include a processor and repository comprising (i) facies data, (ii) sequence stratigraphy, and (iii) a depositional model for a subject reservoir. The processor is operable to generate a 3D stratigraphic sequence framework comprising a plurality of facies based on received facies data and sequence stratigraphy, generate a facies volume fraction for each facies, compare each facies volume fraction with the depositional model for the subject reservoir, reassign the facies volume fraction for the facies of the plurality of facies to another facies of the plurality of facies when the comparison determines that the facies of the 3D stratigraphic sequence framework is incorrectly assigned, generate a plurality of 3D probability trends for the plurality of facies based on the facies volume fraction for the respective facies, and generate the 3D facies model based on the 3D probability trends.

Abstract: An asymmetric nanocomposite supercapacitor and a method of making the asymmetric nanocomposite supercapacitor. The asymmetric nanocomposite supercapacitor includes a negative electrode with monoclinic tungsten oxide (m-WO3) nanoplates, and a binding compound coated on one face of a substrate, and a positive electrode with a carbonaceous material and a binding compound coated on one face of a substrate. Where the face of the positive electrode and the face of the negative electrode coated with the carbonaceous material and m-WO3 nanoplates, respectively, are separated by and in direct contact with a porous separator.

Abstract: A hybrid photoactive heterojunction including a copper vanadate, Cu2V2O7 (CVO) and a zinc vanadate, Zn2V2O6 (ZVO). Particles of the ZVO are dispersed in particles of the CVO to form the hybrid photoactive heterojunction. The hybrid photoactive heterojunction in the form of a photoactive film includes a substrate which is at least partially coated with the hybrid photoactive heterojunction. A method of photodegrading a dye includes contacting the photoactive film and the dye in a solution and exposing the solution to light. A method of photoelectrochemically oxidizing water includes contacting the photoactive film with water in a solution and exposing the solution to light.

Abstract: A hybrid photoactive heterojunction including a copper vanadate, Cu2V2O7 (CVO) and a zinc vanadate, Zn2V2O6 (ZVO). Particles of the ZVO are dispersed in particles of the CVO to form the hybrid photoactive heterojunction. The hybrid photoactive heterojunction in the form of a photoactive film includes a substrate which is at least partially coated with the hybrid photoactive heterojunction. A method of photodegrading a dye includes contacting the photoactive film and the dye in a solution and exposing the solution to light. A method of photoelectrochemically oxidizing water includes contacting the photoactive film with water in a solution and exposing the solution to light.

Abstract: A 3D facies model generator system and methods thereof include a processor and repository comprising (i) facies data, (ii) sequence stratigraphy, and (iii) a depositional model for a subject reservoir. The processor is operable to generate a 3D stratigraphic sequence framework comprising a plurality of facies based on received facies data and sequence stratigraphy, generate a facies volume fraction for each facies, compare each facies volume fraction with the depositional model for the subject reservoir, reassign the facies volume fraction for the facies of the plurality of facies to another facies of the plurality of facies when the comparison determines that the facies of the 3D stratigraphic sequence framework is incorrectly assigned, generate a plurality of 3D probability trends for the plurality of facies based on the facies volume fraction for the respective facies, and generate the 3D facies model based on the 3D probability trends.

Abstract: An asymmetric nanocomposite supercapacitor and a method of making the asymmetric nanocomposite supercapacitor. The asymmetric nanocomposite supercapacitor includes a negative electrode with monoclinic tungsten oxide (m-WO3) nanoplates, and a binding compound coated on one face of a substrate, and a positive electrode with a carbonaceous material and a binding compound coated on one face of a substrate. Where the face of the positive electrode and the face of the negative electrode coated with the carbonaceous material and m-WO3 nanoplates, respectively, are separated by and in direct contact with a porous separator.

Abstract: An asymmetric nanocomposite supercapacitor and a method of making the asymmetric nanocomposite supercapacitor. The asymmetric nanocomposite supercapacitor includes a negative electrode with monoclinic tungsten oxide (m-WO3) nanoplates, and a binding compound coated on one face of a substrate, and a positive electrode with a carbonaceous material and a binding compound coated on one face of a substrate. Where the face of the positive electrode and the face of the negative electrode coated with the carbonaceous material and m-WO3 nanoplates, respectively, are separated by and in direct contact with a porous separator.

Abstract: A hybrid photoactive heterojunction including a copper vanadate, Cu2V2O7 (CVO) and a zinc vanadate, Zn2V2O6 (ZVO). Particles of the ZVO are dispersed in particles of the CVO to form the hybrid photoactive heterojunction. The hybrid photoactive heterojunction in the form of a photoactive film includes a substrate which is at least partially coated with the hybrid photoactive heterojunction. A method of photodegrading a dye includes contacting the photoactive film and the dye in a solution and exposing the solution to light. A method of photoelectrochemically oxidizing water includes contacting the photoactive film with water in a solution and exposing the solution to light.

Abstract: A computer system receives multiple datapoints of a geomechanical property of a hydrocarbon reservoir modeled by a three-dimensional (3D) grid. Each datapoint corresponds to a respective grid cell of the 3D grid. Each grid cell of the 3D grid is represented by 3D coordinates. For each grid cell of the 3D grid, the computer system generates a data component of the geomechanical property based on the 3D coordinates of the grid cell. The computer system adds the data component to a datapoint corresponding to the grid cell to provide an augmented set of datapoints. The computer system transforms the augmented set of datapoints into a Gaussian distribution using Gaussian approximation. The computer system simulates the geomechanical property of the hydrocarbon reservoir based on the Gaussian distribution using sequential Gaussian simulation.

Abstract: A computer system receives multiple datapoints of a geomechanical property of a hydrocarbon reservoir modeled by a three-dimensional (3D) grid. Each datapoint corresponds to a respective grid cell of the 3D grid. Each grid cell of the 3D grid is represented by 3D coordinates. For each grid cell of the 3D grid, the computer system generates a data component of the geomechanical property based on the 3D coordinates of the grid cell. The computer system adds the data component to a datapoint corresponding to the grid cell to provide an augmented set of datapoints. The computer system transforms the augmented set of datapoints into a Gaussian distribution using Gaussian approximation. The computer system simulates the geomechanical property of the hydrocarbon reservoir based on the Gaussian distribution using sequential Gaussian simulation.

Abstract: Steam cell and exosome compositions via combination therapy, related gene therapy and pluripotent stem cell derived muscle regeneration as having therapeutic utility to treat a variety of diseases and disorders, e.g., cardiovascular disease, Duchenne muscular dystrophy, and fibrotic disease.

Abstract: This disclosure provides a chemically modified induced pluripotent stem (iPS) cell derived from parental cells and methods for generating the chemically induced pluripotent stem (iPS) cells, as well as cardiac progenitor cells capable of producing cells of multiple sub-lineages. The iPS cells are useful in method for or regenerating cardiac muscle tissue or to promote the replacement of cardiac scar tissue or to rejuvenating cardiac muscles in a patient in need thereof and to treat cardiac disease.

Abstract: Provided herein are stem cell and exosome compositions having therapeutic utility to treat a variety of diseases and disorders, e.g., cardiovascular disease, Duchenne muscular dystrophy, and fibrotic disease.

Abstract: This disclosure provides a chemically modified induced pluripotent stem (iPS) cell derived from parental cells and methods for generating the chemically induced pluripotent stem (iPS) cells, as well as cardiac progenitor cells capable of producing cells of multiple sub-lineages. The iPS cells are useful in method for or regenerating cardiac muscle tissue or to promote the replacement of cardiac scar tissue or to rejuvenating cardiac muscles in a patient in need thereof and to treat cardiac disease.

Abstract: This disclosure provides a chemically modified induced pluripotent stem (iPS) cells characterized by DNA hypomethylation and methods for generating the cells. The cells are useful in method for or regenerating cardiac muscle tissue or to promote the replacement of cardiac scar tissue in a patient in need thereof and to treat cardiac disease.

Abstract: This disclosure provides a chemically modified induced pluripotent stem (iPS) cells characterized by DNA hypomethylation and methods for generating the cells. The cells are useful in method for or regenerating cardiac muscle tissue or to promote the replacement of cardiac scar tissue in a patient in need thereof and to treat cardiac disease.

Abstract: The present invention provides coated tablet formulations comprising neratinib maleate, and improved methods for making such coated tablets.