Abstract: The present invention relates to a micromechanical photothermal analyser of microfluidic samples comprising an oblong micro-channel extending longitudinally from a support element, the micro-channel is made from at least two materials with different thermal expansion coefficients, wherein the materials are arranged relatively to each other so that heating of the micro-channel results in a bending of the micro-channel, the first material has a first thermal expansion coefficient and is made from an light-specific transparent penetrable material so that when exposed to ultraviolet, visible, or infrared light, the specific light radiates into the channel through said light transparent material, the second material has a second thermal expansion coefficient being different from the first thermal expansion coefficient.

Abstract: The present invention relates to a micron-scale calorimeter and a calorimetry method utilizing the micron-scale calorimeter. In accordance with the invention, there is provided a micron-scale calorimeter comprising a micro-channel string, being restrained at at least two longitudinally distanced positions so as to form a free released double clamped string in-between said two longitudinally distanced positions said micro-channel string comprising a microfluidic channel having a closed cross section and extending in the longitudinal direction of the hollow string, acoustical means adapted to oscillate the string at different frequencies by emitting sound waves towards the string, optical means adapted to detect oscillating frequencies of the string, and controlling means controlling the strength and frequency of the sound wave emitted by the acoustical means and receiving a signal from the optical means representing the detected oscillating frequencies.