Abstract: A vehicle includes a system for charging a battery of the vehicle. An electric motor couples to a charging station. A T-bridge multi-level inverter couples the electric motor to the battery. The inverter includes a first leg having a first set of switches and a first AC terminal coupled to the electric motor, a second leg having a second set of switches and a second AC terminal coupled to the electric motor and a third leg having a third set of switches and a third AC terminal coupled to the electric motor. A processor connects the third AC terminal to the charging station and controls at least one of the first set of switches to control a first current through the first AC terminal of the first leg and the second set of switches to control a second current through second AC terminal of the second leg.

Abstract: A vehicle includes a system for charging a battery of the vehicle. An electric motor couples to a charging station. a diode-clamped multi-level inverter and a processor. A diode-clamped multi-level inverter couples the electric motor to the battery and includes a first leg having a first set of switches and a first AC terminal coupled to the electric motor, a second leg having a second set of switches and a second AC terminal coupled to the electric motor and a third leg having a third set of switches and a third AC terminal coupled to the electric motor. The processor connects the third AC terminal to the charging station and control at least one of the first set of switches to control a first current through the first AC terminal and the second set of switches to control a second current through the second AC terminal to charge the battery.

Abstract: A vehicle includes an inverter having a power module. The power module includes a high side bus, a low side bus and an alternating current (AC) output bus. The high side bus includes a first switch, wherein a high side current is configured to flow through the first switch in a first direction. The high side bus is disposed in a plane. The low side bus includes a second switch, wherein a low side current is configured to flow through the second switch in the first direction. The low side bus is parallel to the high side bus. The alternating current (AC) output bus is parallel to the high side bus and the low side bus, wherein an output current flows through the AC output bus in a second direction opposite to the first direction.

Abstract: A vehicle includes a system for charging a battery of the vehicle. The system includes an electric motor couplable to a charging station, a capacitor-clamped multi-level inverter, and a processor. The capacitor-clamped multi-level inverter is couples the electric motor to the battery and includes a first leg having a first set of switches and a first AC terminal coupled to the electric motor, a second leg having a second set of switches and a second AC terminal coupled to the electric motor and a third leg having a third set of switches and a third AC terminal coupled to the electric motor. The processor connects one of the third AC terminal and a neutral point of the electric motor to the charging station and control at least one of the first set of switches and the second set of switches to charge the battery through the electric motor.

Abstract: In T lymphocytes, p38 mitogen activated protein kinase (MAPK) can be activated through an alternative pathway that involves phosphorylation at tyrosine 323. Disclosed herein is the identification of a minimal region of the growth arrest and DNA damage-inducible alpha (Gadd45?) protein that is required for binding to and inhibition of tyrosine 323-phosphorylated p38 in T cells. The disclosed Gadd45? polypeptides inhibit proliferation of T cells in response to T cell receptor stimulation, inhibit differentiation of T cells into Th1 or Th17 cells, inhibit the production of proinflammatory cytokines, and reduce tumor formation and growth of inflammatory cancers, such as pancreatic cancer.

Abstract: In T lymphocytes, p38 mitogen activated protein kinase (MAPK) can be activated through an alternative pathway that involves phosphorylation at tyrosine 323. Disclosed herein is the identification of a minimal region of the growth arrest and DNA damage-inducible alpha (Gadd45?) protein that is required for binding to and inhibition of tyrosine 323-phosphorylated p38 in T cells. The disclosed Gadd45? polypeptides inhibit proliferation of T cells in response to T cell receptor stimulation, inhibit differentiation of T cells into Th1 or Th17 cells, inhibit the production of proinflammatory cytokines, and reduce tumor formation and growth of inflammatory cancers, such as pancreatic cancer.