Patents by Inventor Muhammad Safadi

Muhammad Safadi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DELAYED RELEASE RASAGILINE FORMULATION
    Publication number: 20120263789
    Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: June 29, 2012
    Publication date: October 18, 2012
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Marina Zholkovsky
  • STABLE LAQUINIMOD PREPARATIONS
    Publication number: 20120225124
    Abstract: The subject invention provides a pharmaceutical composition comprising N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide or the salt thereof; a pharmaceutically acceptable carrier; and not more than 0.5% w/w relative to N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide of 2-Chloro-6-(1-ethyl-N-methyl-2-oxoindoline-3-carboxamido)benzoic acid, 1H,3H-spiro[5-chloro-1-methylquinoline-2,4-dione-3,3?-[1]ethylindolin-[2]-one], or 5-Chloro-N-ethyl-3-hydroxy-1-methyl-2,4-dioxo-N-phenyl-1,2,3,4-tetrahydro-quinoline-3-carboxamide.
    Type: Application
    Filed: May 14, 2012
    Publication date: September 6, 2012
    Inventors: Muhammad Safadi, Daniella Licht, Ioana Lovinger, Aharon M. Eyal, Tomas Fristedt, Karl Jansson
  • Stable laquinimod preparations
    Patent number: 8178127
    Abstract: The subject invention provides a pharmaceutical composition comprising N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide or the salt thereof; a pharmaceutically acceptable carrier; and not more than 0.5% w/w relative to N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide of 2-Chloro-6-(1-ethyl-N-methyl-2-oxoindoline-3-carboxamido)benzoic acid, 1H,3H-spiro[5-chloro-1-methylquinoline-2,4-dione-3,3?-[1]ethylindolin-[2]-one], or 5-Chloro-N-ethyl-3-hydroxy-1-methyl-2,4-dioxo-N-phenyl-1,2,3,4-tetrahydro-quinoline-3-carboxamide.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: May 15, 2012
    Assignee: Teva Pharmaceuticals Industries, Ltd.
    Inventors: Muhammad Safadi, Daniella Licht, Ioana Lovinger, Aharon M. Eyal, Tomas Fristedt, Karl Jansson
  • DELAYED RELEASE RASAGILINE MALATE FORMULATION
    Publication number: 20120100189
    Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: December 23, 2011
    Publication date: April 26, 2012
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Marina Zholkovsky
  • DELAYED RELEASE RASAGILINE FORMULATION
    Publication number: 20120003310
    Abstract: Disclosed are formulations of rasagiline base which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. Also, disclosed are rasagiline citrate salt and the use and process of manufacture thereof.
    Type: Application
    Filed: January 21, 2010
    Publication date: January 5, 2012
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Tamas Koltai, Marina Zholkovsky
  • Delayed release rasagiline citrate formulation
    Patent number: 8080584
    Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: December 20, 2011
    Assignee: Teva Pharmaceuticals Industries, Ltd.
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Marina Zholkovsky
  • Citrate salt of Rasagiline
    Patent number: 7855233
    Abstract: The subject invention provides rasagiline citrate, its compositions and processes for the manufacture thereof.
    Type: Grant
    Filed: January 18, 2010
    Date of Patent: December 21, 2010
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Anton Frenkel, Muhammad Safadi, Tamas Koltai
  • Citrate Salt of Rasagiline
    Publication number: 20100190859
    Abstract: The subject invention provides rasagiline citrate, its compositions and processes for the manufacture thereof.
    Type: Application
    Filed: January 18, 2010
    Publication date: July 29, 2010
    Inventors: Anton Frenkel, Muhammad Safadi, Tamas Koltai
  • Delayed release rasagiline citrate formulation
    Publication number: 20100189787
    Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: June 9, 2009
    Publication date: July 29, 2010
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Marina Zholkovsky
  • Delayed release rasagiline malate formulation
    Publication number: 20100189791
    Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: June 9, 2009
    Publication date: July 29, 2010
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Marina Zholkovsky
  • Delayed release rasagiline base formulation
    Publication number: 20100189788
    Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: June 9, 2009
    Publication date: July 29, 2010
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Marina Zholkovsky
  • Delayed release rasagiline formulation
    Publication number: 20100189790
    Abstract: Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: June 9, 2009
    Publication date: July 29, 2010
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen, Anton Frenkel, Marina Zholkovsky
  • Rasagiline soft gelatin capsules
    Publication number: 20100008983
    Abstract: Disclosed are formulations which are designed to release rasagiline mesylate while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: June 10, 2009
    Publication date: January 14, 2010
    Inventors: Muhammad Safadi, Daniella Licht, Marina Zholkovsky, Fanny Caciularu, Tomas Andrysek, Ales Vrana, Marie Elblova, Roman Stonis
  • Rasagiline formulations, their preparation and use
    Publication number: 20090181086
    Abstract: Disclosed are formulations which are designed to release rasagiline mesylate while maintaining specific pharmacokinetic properties.
    Type: Application
    Filed: January 9, 2009
    Publication date: July 16, 2009
    Inventors: Muhammad Safadi, Daniella Licht, Rachel Cohen
  • Stable laquinimod preparations
    Publication number: 20090162432
    Abstract: The subject invention provides a pharmaceutical composition comprising N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide or the salt thereof; a pharmaceutically acceptable carrier; and not more than 0.5% w/w relative to N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide of 2-Chloro-6-(1-ethyl-N-methyl-2-oxoindoline-3-carboxamido)benzoic acid,1H,3H-spiro[5-chloro-1-methylquinoline-2,4-dione-3,3?-[1]ethylindolin-[2]-one], or 5-Chloro-N-ethyl-3-hydroxy-1-methyl-2,4-dioxo-N-phenyl-1,2,3,4-tetrahydro-quinoline-3-carboxamide.
    Type: Application
    Filed: December 19, 2008
    Publication date: June 25, 2009
    Inventors: Muhammad Safadi, Daniella Licht, Ioana Lovinger, Aharon M. Eyal, Tomas Fristedt, Karl Jansson
  • Water soluble prodrugs of hindered alcohols
    Publication number: 20050090431
    Abstract: The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals.
    Type: Application
    Filed: November 17, 2004
    Publication date: April 28, 2005
    Applicant: University of Kansas
    Inventors: Valentino Stella, Jan Zygmunt, Ingrid Georg, Muhammad Safadi