Abstract: A device for magnetic resonance imaging of a body placed in an examination volume is configured to generate a series of MR spin echo signals from a first nuclear spin species by subjecting at least a portion of the body to an MR imaging pulse sequence. The MR imaging pulse sequence includes a spatially non-selective excitation RF pulse, a plurality of refocusing RF pulses, and a plurality of phase encoding switched magnetic field gradients. The device is further is configured to acquire the MR spin echo signals without application of frequency encoding magnetic field gradients; and to reconstruct an MR image from the acquired MR spin echo signals.

Abstract: Described is the use of perfluoro-t-butyl cyclohexane in a contrast agent for molecular imaging, notably F MRI. Particularly, the perfluoro-t-butyl cyclohexane is present in the form of an aqueous emulsion of nanoparticles comprising the perfluoro compound as a core, and an emulsifying agent, such as a phospholipid, as a shell. The shell can be functionalized with other moieties that play a role in imaging, notably ligands for targeted binding and/or contrast agents or labels with a view to other imaging modalities. The latter particularly refers to 1H MRI contrast agents as well as radiolabels for SPECT.

Abstract: The invention relates to a device for magnetic resonance imaging of a body (7) placed in an examination volume. The device (1) is arranged to a) generate a series of MR spin echo signals from a first nuclear spin species by subjecting at least a portion of the body (7) to an MR imaging pulse sequence comprising a spatially non-selective excitation RF pulse, a plurality of refocusing RF pulses, and a plurality of phase encoding switched magnetic field gradients; b) acquire the MR spin echo signals without application of frequency encoding magnetic field gradients; c) reconstruct an MR image from the acquired MR spin echo signals.