Patents by Inventor Mukund J. Modak

Mukund J. Modak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Structure based design of inhibitors of HIV-1 reverse transcriptase
    Patent number: 5917033
    Abstract: The present invention pertains to a method for designing inhibitors of enzyme human immunodeficiency virus type 1 reverse transcriptase which comprises the steps of:(a) providing a three dimensional model of the receptor site in the prepolymerization complex of the p66 subunit of enzyme human immunodeficiency virus type 1 reverse transcriptase and a known nonnucleoside inhibitor;(b) locating the conserved residues in the p66 subunit which constitute the nonnucleoside inhibitor binding pocket; and(c) designing a new nonnucleoside inhibitor which possesses complementary structural features and binding forces to the residues in the p66 subunit nonnucleoside inhibitor binding pocket.
    Type: Grant
    Filed: October 31, 1995
    Date of Patent: June 29, 1999
    Assignee: University of Medicine & Dentistry of New Jersey
    Inventors: Mukund J. Modak, Prem N. S. Yadav, Janardan S. Yadav