Patents by Inventor Munehide Kano

Munehide Kano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AIDS virus vaccines using Sendai virus vector
    Patent number: 8217019
    Abstract: The present invention provides a vaccine containing a Sendai virus vector encoding a virus protein of an immunodeficiency virus. By intranasally administering a Sendai virus encoding a virus protein of an immunodeficiency virus to a macaque monkey, the present inventors have succeeded in efficiently inducing protective immunity against an immunodeficiency virus. As a result of intranasal inoculation of vaccine, expression of an antigen protein mediated by Sendai virus vector was detected in intranasal mucous membrane and local lymph nodes and antigen-specific cellular immune response was induced at a significant level. No pathological symptom by vaccination was observed. After vaccination, exposure of simian immunodeficiency virus was performed and the effect was examined. As a result, the amount of virus in plasma significantly decreased, compared with that of the control animal. The present invention provides a promising vaccine as an AIDS vaccine.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: July 10, 2012
    Assignees: DNAVEC Research Inc., Japan as Represented by the Director General of National Institute of Infectious Disease
    Inventors: Munehide Kano, Tetsuro Matano, Atsushi Kato, Yoshiyuki Nagai, Mamoru Hasegawa
  • AIDS VIRUS VACCINES USING SENDAI VIRUS VECTOR
    Publication number: 20100266633
    Abstract: The present invention provides a vaccine containing a Sendai virus vector encoding a virus protein of an immunodeficiency virus. By intranasally administering a Sendai virus encoding a virus protein of an immunodeficiency virus to a macaque monkey, the present inventors have succeeded in efficiently inducing protective immunity against an immunodeficiency virus. As a result of intranasal inoculation of vaccine, expression of an antigen protein mediated by Sendai virus vector was detected in intranasal mucous membrane and local lymph nodes and antigen-specific cellular immune response was induced at a significant level. No pathological symptom by vaccination was observed. After vaccination, exposure of simian immunodeficiency virus was performed and the effect was examined. As a result, the amount of virus in plasma significantly decreased, compared with that of the control animal. The present invention provides a promising vaccine as an AIDS vaccine.
    Type: Application
    Filed: February 5, 2010
    Publication date: October 21, 2010
    Applicants: DNAVEC Research Inc., Japan as represented by Director General of National Institute of Infectious Diseases
    Inventors: Munehide KANO, Tetsuro Matano, Atsushi Kato, Yoshiyuki Nagai, Mamoru Hasegawa
  • AIDS virus vaccines using sendai virus vector
    Publication number: 20020002143
    Abstract: The present invention provides a vaccine containing a Sendai virus vector encoding a virus protein of an immunodeficiency virus. By intranasally administering a Sendai virus encoding a virus protein of an immunodeficiency virus to a macaque monkey, the present inventors have succeeded in efficiently inducing protective immunity against an immunodeficiency virus. As a result of intranasal inoculation of vaccine, expression of an antigen protein mediated by Sendai virus vector was detected in intranasal mucous membrane and local lymph nodes and antigen-specific cellular immune response was induced at a significant level. No pathological symptom by vaccination was observed. After vaccination, exposure of simian immunodeficiency virus was performed and the effect was examined. As a result, the amount of virus in plasma significantly decreased, compared with that of the control animal. The present invention provides a promising vaccine as an AIDS vaccine.
    Type: Application
    Filed: March 30, 2001
    Publication date: January 3, 2002
    Inventors: Munehide Kano, Tetsuro Matano, Atsushi Kato, Yoshiyuki Nagai, Mamoru Hasegawa