Patents by Inventor Munehiko Hirano

Munehiko Hirano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100249236
    Abstract: An adhesive comprising a base with tackiness, an oil and ketoprofen, wherein the adhesive contains no L-menthol, the base is composed at least of a tacky composition comprising an elastomer and a tackifier and/or a tacky polymer containing an unsaturated monomer with a total of 5 or more carbon atoms as the monomer unit, the oil is an oil that is compatible with the tacky composition and the tacky polymer, and the oil content is 150-175 parts by weight with respect to 100 parts by weight as the total of the tacky composition and the tacky polymer.
    Type: Application
    Filed: June 7, 2010
    Publication date: September 30, 2010
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Munehiko HIRANO, Miyuki SHINMURA, Kiyomi TSURUDA
  • Publication number: 20080292670
    Abstract: An adhesive comprising a base with tackiness, an oil and ketoprofen, wherein the adhesive contains no L-menthol, the base is composed at least of a tacky composition comprising an elastomer and a tackifier and/or a tacky polymer containing an unsaturated monomer with a total of 5 or more carbon atoms as the monomer unit, the oil is an oil that is compatible with the tacky composition and the tacky polymer, and the oil content is 150-175 parts by weight with respect to 100 parts by weight as the total of the tacky composition and the tacky polymer.
    Type: Application
    Filed: July 31, 2008
    Publication date: November 27, 2008
    Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
    Inventors: Munehiko Hirano, Miyuki Shinmura, Kiyomi Tsuruda
  • Publication number: 20060263420
    Abstract: An adhesive comprising a base with tackiness, an oil and ketoprofen, wherein the adhesive contains no L-menthol, the base is composed at least of a tacky composition comprising an elastomer and a tackifier and/or a tacky polymer containing an unsaturated monomer with a total of 5 or more carbon atoms as the monomer unit, the oil is an oil that is compatible with the tacky composition and the tacky polymer, and the oil content is 150-175 parts by weight with respect to 100 parts by weight as the total of the tacky composition and the tacky polymer.
    Type: Application
    Filed: March 9, 2006
    Publication date: November 23, 2006
    Applicant: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Munehiko Hirano, Miyuki Shinmura, Kiyomi Tsuruda
  • Patent number: 6936268
    Abstract: A sheet-form adhesive preparation which gives a comfortable refreshing feeling in use, gives a wet feeling to the skin, and is usable a a cosmetic, medicinal, or quasi-drug preparation for the sake of skin adjustment and beauty. The preparation preferably has a quantity of heat required for water evaporation of 0.6 to 13 (cal) per unit area (cm2) when exposed for 30 minutes to an atmosphere of 25° C. and 60% Rh.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: August 30, 2005
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kazunori Muta, Yasuhisa Kose, Munehiko Hirano
  • Publication number: 20030229048
    Abstract: Compositions for reducing an adverse skin reaction caused by a skin-irritating agent or skin sensitizing agent by treatment with a disaccharide and a metal ion, as well as methods for reducing an adverse skin reaction caused by a skin-irritating or skin-sensitizing agent, and methods for treating an inflammatory response to at least one inflammatory agent, by application of a disaccharide and/or metal ion composition.
    Type: Application
    Filed: April 30, 2003
    Publication date: December 11, 2003
    Inventors: Dange Veerapaneni, Kazutaka Inoue, Takaaki Yoshinaga, Munehiko Hirano, Shuji Sato
  • Patent number: 6495159
    Abstract: A device for perutaneous treatment by a serotonin receptor antagonist, comprising at least three layers including A) a drug-impermeable backing layer, B) a drug storage layer provided between the packing layer and a drug release layer and containing serotonin receptor antagonist, and C) a drug release layer constituted of a pressure-sensitive adhesive layer capable of controlling the release of a drug.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: December 17, 2002
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Munehiko Hirano, Masayoshi Maki, Tatsuaki Suzuki
  • Publication number: 20020102290
    Abstract: A device for perutaneous treatment by a serotonin receptor antagonist, comprising at least three layers including A) a drug-impermeable backing layer, B) a drug storage layer provided between the packing layer and a drug release layer and containing serotonin receptor antagonist, and C) a drug release layer constituted of a pressure-sensitive adhesive layer capable of controlling the release of a drug.
    Type: Application
    Filed: June 8, 1999
    Publication date: August 1, 2002
    Inventors: MUNEHIKO HIRANO, MASAYOSHI MAKI, TATSUAKI SUZUKI
  • Patent number: 5891920
    Abstract: A drug solubilizer or drug-absorption accelerator of Formula I is disclosed wherein R.sub.1 and R.sub.
    Type: Grant
    Filed: March 31, 1997
    Date of Patent: April 6, 1999
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Munehiko Hirano, Mitsuru Kuribayashi, Mitsuhiko Kido
  • Patent number: 5869087
    Abstract: A preparation for external use in application to the body, which comprises an antiphlogistic with carboxylic groups in the molecule, l-menthol and a metal salt of a fatty acid; and a patch having the preparation spread thereon for easier application to the body.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: February 9, 1999
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Munehiko Hirano, Kiyomi Tsuruta
  • Patent number: 5820878
    Abstract: A percutaneously absorbable preparation-containing patch, wherein the preparation comprises: (1) a base comprising as essential ingredients a (A-B) n-A based elastomer wherein A is substantially a monovinyl-substituted aromatic compound polymer block, B is substantially a conjugated diolefin copolymer block, and n is an integer of 3-7, crotamiton, and a softening agent; and (2) at least two hormones, especially estrogen and luteal hormones, as active ingredients.
    Type: Grant
    Filed: April 28, 1997
    Date of Patent: October 13, 1998
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Munehiko Hirano, Miyuki Shinmura, Masaki Kojima
  • Patent number: 5756857
    Abstract: A cyclohexanol derivative represented by the following general formula (1) and preferably the following general formula (1a): ##STR1## wherein R represents a linear or branched alkyl group having 1 to 5 carbon atoms. The above cyclohexanol derivative imparts satisfactory refrigeration to not only the mouth mucosa but also the skin. Moreover, it is practically odorless. A cool feeling and various cool feeling compositions which are practically odorless can be obtained from the cyclohexanol derivative.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: May 26, 1998
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Mitsuru Kuribayashi, Mitsuru Tanoue, Akira Nakagawa, Munehiko Hirano, Hideshi Oda
  • Patent number: 5725874
    Abstract: Percutaneously absorbable preparations which comprise, by weight, 0.001 to 20%, preferably 0.1 to 20%, of 3-l-menthoxy-propane-1,2-diol as a solubilizer for a drug and 0.001 to 20%, preferably 0.5 to 10%, of the drug as two essential ingredients, the balance being other ingredients as adjuvants selected from water-soluble polymers, monohydric alcohols, polyhydric alcohols, rosin esters, water, fatty acid esters, hydrocarbons, softening agents, emulsifying agents. The preparations are in the forms of poultice, plasters, ointments, gels, creams, gel-like creams, lotions, reserver patches, liniments, aerosols and may be used in packs.
    Type: Grant
    Filed: November 16, 1995
    Date of Patent: March 10, 1998
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Hideshi Oda, Tetsuro Tateishi, Akira Nakagawa, Munehiko Hirano, Koki Shoho
  • Patent number: 5519046
    Abstract: A fomentation containing ketorolac, one of nonsteroidal anti-inflammatory analgesics, or a salt thereof as the efficacious ingredient, and a base comprising a water-soluble high-molecular substance, a humectant, water and, if necessary, an absorption promoter.
    Type: Grant
    Filed: May 6, 1994
    Date of Patent: May 21, 1996
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kanji Noda, Masaru Saita, Munehiko Hirano, Yasuhiro Ikeura, Yasuaki Taniguchi, Terushi Hashiguchi, Yasuhisa Kose, Yasunori Takada, Eiji Kyoya, Akira Nakagawa
  • Patent number: 5478567
    Abstract: An antiphlogistic analgesic plaster which comprises as essential ingredients:(a) at least one nonsteroidal antiphlogistic analgesic drug selected from among ketoprofen, flurbiprofen, loxoprofen, ketorolac and ester derivatives or salts thereof,(b) a solubilizer comprising a combination of a rosin ester derivative with l-menthol,(e) a styrene/isoprene/styrene block copolymer employed as a base polymer,(d) a softener, and(e) a backing comprising a polyester cloth.
    Type: Grant
    Filed: March 21, 1994
    Date of Patent: December 26, 1995
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Akira Nakagawa, Munehiko Hirano, Tetsuro Tateishi
  • Patent number: 5248676
    Abstract: 1. An estradiol percutaneous administration preparation comprising:(1) a (A-B) nX or (A-B) n-A type elastomer wherein A is substantially monovinyl-substituted aromatic compound polymer block, B is substantially a conjugated diolefin copolymer block, n is an integer of 3-7, and X is a residue derived from a polyfunctional compound combined with n of polymer chain (A-B),(2) crotamiton and(3) a super absorbent polymer, the preparation further comprising estradiol as the medicinal ingredient and exhibiting sufficient medicinal efficacy without causing rubefaction, rashes and the like.
    Type: Grant
    Filed: March 9, 1992
    Date of Patent: September 28, 1993
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Akira Nakagawa, Munehiko Hirano, Miyuki Shinmura
  • Patent number: 4410546
    Abstract: An antiallergic composition comprising, as the effective ingredient, a compound represented by the following general formula ##STR1## wherein R is n-butyl group or n-pentyl group, the compound being preferably supported by a carrier such as sugar, starch, gum arabic or calcium stearate.
    Type: Grant
    Filed: May 5, 1981
    Date of Patent: October 18, 1983
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kanji Noda, Akira Nakagawa, Munehiko Hirano, Kenji Yamagata, Yoichi Nakashima, Terumi Hachiya, Hiroyuki Ide, Akihide Koda
  • Patent number: 4395405
    Abstract: An alkyl-ketohexopyranoside derivative having pharmacological actions such as antiallergic actions, represented by the following general formula ##STR1## wherein R is an alkyl group having at least 3 carbon atoms, the derivatives excluding the D-fructose derivative wherein R is n-propyl group.
    Type: Grant
    Filed: May 15, 1980
    Date of Patent: July 26, 1983
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kanji Noda, Akira Nakagawa, Yasushi Haraguchi, Koichiro Ueda, Munehiko Hirano, Itsuo Nishioka, Akira Yagi, Akihide Koda, Hiroyuki Ide