Patents by Inventor Munehiko Hirano
Munehiko Hirano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100249236Abstract: An adhesive comprising a base with tackiness, an oil and ketoprofen, wherein the adhesive contains no L-menthol, the base is composed at least of a tacky composition comprising an elastomer and a tackifier and/or a tacky polymer containing an unsaturated monomer with a total of 5 or more carbon atoms as the monomer unit, the oil is an oil that is compatible with the tacky composition and the tacky polymer, and the oil content is 150-175 parts by weight with respect to 100 parts by weight as the total of the tacky composition and the tacky polymer.Type: ApplicationFiled: June 7, 2010Publication date: September 30, 2010Applicant: HISAMITSU PHARMACEUTICAL CO., INC.Inventors: Munehiko HIRANO, Miyuki SHINMURA, Kiyomi TSURUDA
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Publication number: 20080292670Abstract: An adhesive comprising a base with tackiness, an oil and ketoprofen, wherein the adhesive contains no L-menthol, the base is composed at least of a tacky composition comprising an elastomer and a tackifier and/or a tacky polymer containing an unsaturated monomer with a total of 5 or more carbon atoms as the monomer unit, the oil is an oil that is compatible with the tacky composition and the tacky polymer, and the oil content is 150-175 parts by weight with respect to 100 parts by weight as the total of the tacky composition and the tacky polymer.Type: ApplicationFiled: July 31, 2008Publication date: November 27, 2008Applicant: HISAMITSU PHARMACEUTICAL CO., INC.Inventors: Munehiko Hirano, Miyuki Shinmura, Kiyomi Tsuruda
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Publication number: 20060263420Abstract: An adhesive comprising a base with tackiness, an oil and ketoprofen, wherein the adhesive contains no L-menthol, the base is composed at least of a tacky composition comprising an elastomer and a tackifier and/or a tacky polymer containing an unsaturated monomer with a total of 5 or more carbon atoms as the monomer unit, the oil is an oil that is compatible with the tacky composition and the tacky polymer, and the oil content is 150-175 parts by weight with respect to 100 parts by weight as the total of the tacky composition and the tacky polymer.Type: ApplicationFiled: March 9, 2006Publication date: November 23, 2006Applicant: Hisamitsu Pharmaceutical Co., Inc.Inventors: Munehiko Hirano, Miyuki Shinmura, Kiyomi Tsuruda
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Patent number: 6936268Abstract: A sheet-form adhesive preparation which gives a comfortable refreshing feeling in use, gives a wet feeling to the skin, and is usable a a cosmetic, medicinal, or quasi-drug preparation for the sake of skin adjustment and beauty. The preparation preferably has a quantity of heat required for water evaporation of 0.6 to 13 (cal) per unit area (cm2) when exposed for 30 minutes to an atmosphere of 25° C. and 60% Rh.Type: GrantFiled: February 18, 2000Date of Patent: August 30, 2005Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Kazunori Muta, Yasuhisa Kose, Munehiko Hirano
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Publication number: 20030229048Abstract: Compositions for reducing an adverse skin reaction caused by a skin-irritating agent or skin sensitizing agent by treatment with a disaccharide and a metal ion, as well as methods for reducing an adverse skin reaction caused by a skin-irritating or skin-sensitizing agent, and methods for treating an inflammatory response to at least one inflammatory agent, by application of a disaccharide and/or metal ion composition.Type: ApplicationFiled: April 30, 2003Publication date: December 11, 2003Inventors: Dange Veerapaneni, Kazutaka Inoue, Takaaki Yoshinaga, Munehiko Hirano, Shuji Sato
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Patent number: 6495159Abstract: A device for perutaneous treatment by a serotonin receptor antagonist, comprising at least three layers including A) a drug-impermeable backing layer, B) a drug storage layer provided between the packing layer and a drug release layer and containing serotonin receptor antagonist, and C) a drug release layer constituted of a pressure-sensitive adhesive layer capable of controlling the release of a drug.Type: GrantFiled: June 8, 1999Date of Patent: December 17, 2002Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Munehiko Hirano, Masayoshi Maki, Tatsuaki Suzuki
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Publication number: 20020102290Abstract: A device for perutaneous treatment by a serotonin receptor antagonist, comprising at least three layers including A) a drug-impermeable backing layer, B) a drug storage layer provided between the packing layer and a drug release layer and containing serotonin receptor antagonist, and C) a drug release layer constituted of a pressure-sensitive adhesive layer capable of controlling the release of a drug.Type: ApplicationFiled: June 8, 1999Publication date: August 1, 2002Inventors: MUNEHIKO HIRANO, MASAYOSHI MAKI, TATSUAKI SUZUKI
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Patent number: 5891920Abstract: A drug solubilizer or drug-absorption accelerator of Formula I is disclosed wherein R.sub.1 and R.sub.Type: GrantFiled: March 31, 1997Date of Patent: April 6, 1999Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Munehiko Hirano, Mitsuru Kuribayashi, Mitsuhiko Kido
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Patent number: 5869087Abstract: A preparation for external use in application to the body, which comprises an antiphlogistic with carboxylic groups in the molecule, l-menthol and a metal salt of a fatty acid; and a patch having the preparation spread thereon for easier application to the body.Type: GrantFiled: February 27, 1997Date of Patent: February 9, 1999Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Munehiko Hirano, Kiyomi Tsuruta
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Patent number: 5820878Abstract: A percutaneously absorbable preparation-containing patch, wherein the preparation comprises: (1) a base comprising as essential ingredients a (A-B) n-A based elastomer wherein A is substantially a monovinyl-substituted aromatic compound polymer block, B is substantially a conjugated diolefin copolymer block, and n is an integer of 3-7, crotamiton, and a softening agent; and (2) at least two hormones, especially estrogen and luteal hormones, as active ingredients.Type: GrantFiled: April 28, 1997Date of Patent: October 13, 1998Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Munehiko Hirano, Miyuki Shinmura, Masaki Kojima
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Patent number: 5756857Abstract: A cyclohexanol derivative represented by the following general formula (1) and preferably the following general formula (1a): ##STR1## wherein R represents a linear or branched alkyl group having 1 to 5 carbon atoms. The above cyclohexanol derivative imparts satisfactory refrigeration to not only the mouth mucosa but also the skin. Moreover, it is practically odorless. A cool feeling and various cool feeling compositions which are practically odorless can be obtained from the cyclohexanol derivative.Type: GrantFiled: April 25, 1995Date of Patent: May 26, 1998Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Mitsuru Kuribayashi, Mitsuru Tanoue, Akira Nakagawa, Munehiko Hirano, Hideshi Oda
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Patent number: 5725874Abstract: Percutaneously absorbable preparations which comprise, by weight, 0.001 to 20%, preferably 0.1 to 20%, of 3-l-menthoxy-propane-1,2-diol as a solubilizer for a drug and 0.001 to 20%, preferably 0.5 to 10%, of the drug as two essential ingredients, the balance being other ingredients as adjuvants selected from water-soluble polymers, monohydric alcohols, polyhydric alcohols, rosin esters, water, fatty acid esters, hydrocarbons, softening agents, emulsifying agents. The preparations are in the forms of poultice, plasters, ointments, gels, creams, gel-like creams, lotions, reserver patches, liniments, aerosols and may be used in packs.Type: GrantFiled: November 16, 1995Date of Patent: March 10, 1998Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Hideshi Oda, Tetsuro Tateishi, Akira Nakagawa, Munehiko Hirano, Koki Shoho
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Patent number: 5519046Abstract: A fomentation containing ketorolac, one of nonsteroidal anti-inflammatory analgesics, or a salt thereof as the efficacious ingredient, and a base comprising a water-soluble high-molecular substance, a humectant, water and, if necessary, an absorption promoter.Type: GrantFiled: May 6, 1994Date of Patent: May 21, 1996Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Kanji Noda, Masaru Saita, Munehiko Hirano, Yasuhiro Ikeura, Yasuaki Taniguchi, Terushi Hashiguchi, Yasuhisa Kose, Yasunori Takada, Eiji Kyoya, Akira Nakagawa
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Patent number: 5478567Abstract: An antiphlogistic analgesic plaster which comprises as essential ingredients:(a) at least one nonsteroidal antiphlogistic analgesic drug selected from among ketoprofen, flurbiprofen, loxoprofen, ketorolac and ester derivatives or salts thereof,(b) a solubilizer comprising a combination of a rosin ester derivative with l-menthol,(e) a styrene/isoprene/styrene block copolymer employed as a base polymer,(d) a softener, and(e) a backing comprising a polyester cloth.Type: GrantFiled: March 21, 1994Date of Patent: December 26, 1995Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Akira Nakagawa, Munehiko Hirano, Tetsuro Tateishi
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Patent number: 5248676Abstract: 1. An estradiol percutaneous administration preparation comprising:(1) a (A-B) nX or (A-B) n-A type elastomer wherein A is substantially monovinyl-substituted aromatic compound polymer block, B is substantially a conjugated diolefin copolymer block, n is an integer of 3-7, and X is a residue derived from a polyfunctional compound combined with n of polymer chain (A-B),(2) crotamiton and(3) a super absorbent polymer, the preparation further comprising estradiol as the medicinal ingredient and exhibiting sufficient medicinal efficacy without causing rubefaction, rashes and the like.Type: GrantFiled: March 9, 1992Date of Patent: September 28, 1993Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Akira Nakagawa, Munehiko Hirano, Miyuki Shinmura
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Patent number: 4410546Abstract: An antiallergic composition comprising, as the effective ingredient, a compound represented by the following general formula ##STR1## wherein R is n-butyl group or n-pentyl group, the compound being preferably supported by a carrier such as sugar, starch, gum arabic or calcium stearate.Type: GrantFiled: May 5, 1981Date of Patent: October 18, 1983Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Kanji Noda, Akira Nakagawa, Munehiko Hirano, Kenji Yamagata, Yoichi Nakashima, Terumi Hachiya, Hiroyuki Ide, Akihide Koda
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Patent number: 4395405Abstract: An alkyl-ketohexopyranoside derivative having pharmacological actions such as antiallergic actions, represented by the following general formula ##STR1## wherein R is an alkyl group having at least 3 carbon atoms, the derivatives excluding the D-fructose derivative wherein R is n-propyl group.Type: GrantFiled: May 15, 1980Date of Patent: July 26, 1983Assignee: Hisamitsu Pharmaceutical Co., Inc.Inventors: Kanji Noda, Akira Nakagawa, Yasushi Haraguchi, Koichiro Ueda, Munehiko Hirano, Itsuo Nishioka, Akira Yagi, Akihide Koda, Hiroyuki Ide