Abstract: To avoid discontinuities between echoes from becoming large level differences in a k-space and to reduce artifacts generated in a reconstructed image due to the discontinuities in the k-space, an MRI apparatus of the present invention uses phase characteristics of multiple echoes to be collected after a single RF excitation to control an arrangement order in the k-space where the multiple echoes are arranged when a pulse sequence of the fast spin echo method that collects the multiple echoes using a spin flip after a single RF excitation is executed. The arrangement is controlled so that echoes with small phase errors between the echoes at least near the center of the k-space are adjacent to each other.

Abstract: To avoid discontinuities between echoes from becoming large level differences in a k-space and to reduce artifacts generated in a reconstructed image due to the discontinuities in the k-space, an MRI apparatus of the present invention uses phase characteristics of multiple echoes to be collected after a single RF excitation to control an arrangement order in the k-space where the multiple echoes are arranged when a pulse sequence of the fast spin echo method that collects the multiple echoes using a spin flip after a single RF excitation is executed. The arrangement is controlled so that echoes with small phase errors between the echoes at least near the center of the k-space are adjacent to each other.

Abstract: A method for preparing neoplastically transformed cells from human-derived cells, including the step of introducing human telomerase catalytic subunit (hTERT) gene, SV40 small T antigen (SV40ST) gene, and an antisense oligonucleotide derived from human 28S rRNA into the human-derived cells. The method for preparing neoplastically transformed cells from human-derived cells can be utilized when a variety of human normal cells are induced to be neoplastically transformed in order to elucidate cancer onset mechanisms, so that the method can be effectively utilized in search of target molecules for a new medicament.