Patents by Inventor Muneyasu Urano

Muneyasu Urano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic test and therapy for manganese superoxide dismutate (mNsod) associated diseases
    Patent number: 6265172
    Abstract: The present invention provides a diagnostic method and a kit for detection of mutations localized within the 5′ promoter region of the MnSOD gene. Such mutations are associated with diseases characterized by decreased MnSOD activity such as certain formes of cancer, and ALS. Accordingly, the diagnostic method this invention provides, comprising RFLP, direct sequencing, or PCR analysis of the region within 3 kb, the transcription initiation site will detect these disorders. This invention also provides a therapeutic method for such disorders comprising transfection of affected cells or tissues with high activity, MnSOD expression vectors, or the administration of exogenous MnSOD enzyme.
    Type: Grant
    Filed: February 8, 2000
    Date of Patent: July 24, 2001
    Assignee: University of Kentucky
    Inventors: Daret K. St. Clair, Muneyasu Urano, Edward J. Kasarskis