Patents by Inventor Murali Cherukuri

Murali Cherukuri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of a nitroxide or a prodrug thereof in the prophylactic and therapeutic treatment of cancer
    Publication number: 20070021323
    Abstract: The present invention provides a method for the prophylactic and therapeutic treatment of cancer. The method comprises administering to an animal, preferably a mammal, more preferably a human, at risk for developing a cancer or having a cancer a nitroxide or a prodrug thereof, wherein the nitroxide or prodrug thereof preferably is alicyclic or heterocyclic and more preferably is a compound of Formula I or Formula II: in an amount sufficient to prevent or treat said cancer, wherein said cancer is susceptible to prevention or treatment by said nitroxide or prodrug thereof. Also provided is a composition for use in the method.
    Type: Application
    Filed: September 21, 2006
    Publication date: January 25, 2007
    Applicants: Dept. of Health and Human Services Office of Technology Transfer
    Inventors: James Mitchell, Angelo Russo, Murali Cherukuri, Anne DeLuca
  • Pulsed low frequency EPR spectrometer and imager
    Patent number: 5502386
    Abstract: An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.
    Type: Grant
    Filed: November 15, 1994
    Date of Patent: March 26, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: John Bourg, James Mitchell, Mark Mirotznik, Bradley Roth, Sankaran Subramanian, Murali Cherukuri, Paul G. Zablocky, Thomas J. Pohida, Paul D. Smith, Walter S. Friauf, Rolf G. Tschudin
  • Pulsed low frequency EPR spectrometer and imager
    Patent number: 5387867
    Abstract: An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: February 7, 1995
    Assignee: The United States of America as represented by the Dept. of Health and Human Services
    Inventors: John Bourg, James Mitchell, Mark Mirotznik, Bradley Roth, Sankaran Subramanian, Murali Cherukuri, Paul G. Zablocky