Patents by Inventor Murali K. Vuppala

Murali K. Vuppala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230414520
    Abstract: An improved immediate release solid dosage form of naproxen with a certain particle size distribution for the intragranular portion, and a certain particle size distribution for the carbonate portion that allows naproxen to remain in solution and achieves fast dissolution and fast absorption of naproxen. The invention provides a naproxen dosage form that when administered to a human in a fasted state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 10 minutes or less. The invention also provides a naproxen dosage form that when administered to a human in a fed state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 50 minutes or less.
    Type: Application
    Filed: September 1, 2023
    Publication date: December 28, 2023
    Inventors: Jitendra Krishan Somani, Murali K. Vuppala
  • Patent number: 11779541
    Abstract: An improved immediate release solid dosage form of naproxen with a certain particle size distribution for the intragranular portion, and a certain particle size distribution for the carbonate portion that allows naproxen to remain in solution and achieves fast dissolution and fast absorption of naproxen. The invention provides a naproxen dosage form that when administered to a human in a fasted state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 10 minutes or less. The invention also provides a naproxen dosage form that when administered to a human in a fed state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 50 minutes or less.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: October 10, 2023
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Jitendra Krishan Somani, Murali K. Vuppala
  • Publication number: 20200306192
    Abstract: An improved immediate release solid dosage form of naproxen with a certain particle size distribution for the intragranular portion, and a certain particle size distribution for the carbonate portion that allows naproxen to remain in solution and achieves fast dissolution and fast absorption of naproxen. The invention provides a naproxen dosage form that when administered to a human in a fasted state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 10 minutes or less. The invention also provides a naproxen dosage form that when administered to a human in a fed state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 50 minutes or less.
    Type: Application
    Filed: March 26, 2019
    Publication date: October 1, 2020
    Inventors: Jitendra Krishan Somani, Murali K. Vuppala
  • Patent number: 10022349
    Abstract: Cadotril particles suitable for solid or liquid dosage forms are the subject of this application.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: July 17, 2018
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Saumitra Bagchi, Murali K. Vuppala
  • Publication number: 20160120834
    Abstract: Cadotril particles suitable for solid or liquid dosage forms are disclosed
    Type: Application
    Filed: October 29, 2015
    Publication date: May 5, 2016
    Inventors: Saumitra Bagchi, Murali K. Vuppala
  • Publication number: 20160051678
    Abstract: Low melting propionic acid derivative particles that are free flowing and have significantly reduced or eliminated throat burn are disclosed. A method of manufacturing the low melting propionic acid derivative particles; dosage forms containing the low melting propionic acid derivative particles; methods of manufacturing the dosage forms; and methods of treatment using the dosage forms are also disclosed.
    Type: Application
    Filed: August 27, 2015
    Publication date: February 25, 2016
    Inventors: Saumitra Bagchi, Murali K. Vuppala
  • Publication number: 20140256810
    Abstract: Low melting propionic acid derivative particles that are free flowing and have significantly reduced or eliminated throat burn are disclosed. A method of manufacturing the low melting propionic acid derivative particles; dosage forms containing the low melting propionic acid derivative particles; methods of manufacturing the dosage forms; and methods of treatment using the dosage forms are also disclosed.
    Type: Application
    Filed: March 8, 2013
    Publication date: September 11, 2014
    Applicant: MCNEIL-PPC, INC.
    Inventors: Saumitra Bagchi, Murali K. Vuppala
  • Publication number: 20140213653
    Abstract: A compressed tablet containing directly compressible propionic acid derivative particles is disclosed. A method of manufacturing a compressed tablet containing the directly compressible propionic acid derivative particles; and methods of treatment using the compressed tablet are also disclosed.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicant: McNeil-PPC, Inc.
    Inventors: Saumitra Bagchi, Murali K. Vuppala
  • Publication number: 20140079796
    Abstract: Low melting propionic acid derivative particles that are free flowing and have significantly reduced or eliminated throat burn are disclosed. A method of manufacturing the low melting propionic acid derivative particles; dosage forms containing the low melting propionic acid derivative particles; methods of manufacturing the dosage forms; and methods of treatment using the dosage forms are also disclosed.
    Type: Application
    Filed: September 16, 2013
    Publication date: March 20, 2014
    Applicant: McNeil-PPC, Inc.
    Inventors: Saumitra Bagchi, Murali K. Vuppala
  • Publication number: 20140080912
    Abstract: Low melting propionic acid derivative particles that are free flowing and have significantly reduced or eliminated throat burn are disclosed. A method of manufacturing the low melting propionic acid derivative particles; dosage forms containing the low melting propionic acid derivative particles; methods of manufacturing the dosage forms; and methods of treatment using the dosage forms are also disclosed.
    Type: Application
    Filed: September 16, 2013
    Publication date: March 20, 2014
    Applicant: McNeil-PPC, Inc.
    Inventors: Saumitra Bagchi, Murali K. Vuppala